Details for Patent: 5,089,509

Summary for Patent: 5,089,509

Title:	Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
Abstract:	Retinoid-like activity is exhibited by compounds of the formula ##STR1## where X is S, O, or NR' where R' is hydrogen or lower alkyl; R is hydrogen or lower alkyl; A is pyridyl, thienyl, furyl, pyridazinyl, pyrimidinyl or pyrazinyl; n is 0-2; and B is H, --COOH or a pharmaceutically acceptable salt, ester or amide thereof, --CH.sub.2 OH or an ether or ester derivative, or --CHO or an acetal derivative, or --COR.sub.1 or a ketal derivative where R.sub.1 is --(CH.sub.2).sub.m CH.sub.3 where m is 0-4, or a pharmaceutically acceptable salt thereof.
Inventor(s):	Chandraratna; Roshantha A. S. (El Toro, CA)
Assignee:	Allergan, Inc. (Irvine, CA)
Application Number:	07/326,191
Patent Claim Types: see list of patent claims	Compound; Composition; Use;

Drugs Protected by US Patent 5,089,509

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

International Family Members for US Patent 5,089,509

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	0284288		SPC/GB98/002	United Kingdom
European Patent Office	0284288		12/1998	Austria
Austria	200284