Details for Patent: 5,135,950

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Summary for Patent: 5,135,950

Patent landscape, scope, and claims:

Title:	Stable polymorphic form of (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide and the process for its preparation
Abstract:	Stable and crystallographically essentially pure polymorphic form A of (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitro-phenyl)acrylamide may be prepared by crystallizing crude synthesis product from lower aliphatic carboxylic acid such as formic or acetic acid with a catalytic amount of hydrochloric or hydrobromic acid added. The product is a potent inhibitor of catechol-O-methyl-transferase enzyme (COMT).
Inventor(s):	Pippuri; Aino K. (Espoo, FI), Honkanen; Erkki J. (Vantaa, FI), Haarala; Jorma V. (Helsinki, FI)
Assignee:	Orion-yhtyma Oy (Espoo, FI)
Application Number:	07/606,717
Patent Claim Types: see list of patent claims	Compound; Process; Use; Composition;
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Drugs Protected by US Patent 5,135,950

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

Foreign Priority and PCT Information for Patent: 5,135,950

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
United Kingdom	8924838.9	Nov 03, 1989

International Family Members for US Patent 5,135,950

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	0426468	⤷ Subscribe	91071	Luxembourg	⤷ Subscribe
European Patent Office	0426468	⤷ Subscribe	CA 2004 00007	Denmark	⤷ Subscribe
European Patent Office	0426468	⤷ Subscribe	C00426468/01	Switzerland	⤷ Subscribe
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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