Details for Patent: 5,145,684
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Summary for Patent: 5,145,684
Title: | Surface modified drug nanoparticles |
Abstract: | Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm, methods for the preparation of such particles and dispersions containing the particles. Pharmaceutical compositions containing the particles exhibit unexpected bioavailability and are useful in methods of treating mammals. |
Inventor(s): | Liversidge; Gary G. (West Chester, PA), Cundy; Kenneth C. (Pottstown, PA), Bishop; John F. (Rochester, NY), Czekai; David A. (Honeoye Falls, NY) |
Assignee: | Sterling Drug Inc. (New York, NY) |
Application Number: | 07/647,105 |
Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
Drugs Protected by US Patent 5,145,684
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