Details for Patent: 5,192,741

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Summary for Patent: 5,192,741

Title:	Sustained and controlled release of water insoluble polypeptides
Abstract:	There is disclosed a pharaceutical composition for sustained and controlled release of drug over an extended period of time comprising a polylactide, a copolymer of lactic and glycolic acid, a mixture of such polymers and a water-insoluble peptide which, when placed in an aqueous physiologically-type environment releases the peptide in continuous manner for a period of at least one week, and with an initial release for the first twenty-four hours of not more than 30% of the total amount released. There is thus provided the control of the release pattern and in general a decrease of the initial burst effect.
Inventor(s):	Orsolini; Piero (Martigny, CH), Mauvernay; Rolland-Yves (Lausanne, CH), Deghenghi; Romano (Lausanne, CH)
Assignee:	Debiopharm S.A. (Lausanne, CH)
Application Number:	07/247,060
Patent Claim Types: see list of patent claims	Composition; Process; Dosage form; Delivery; Formulation;

Drugs Protected by US Patent 5,192,741

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

Foreign Priority and PCT Information for Patent: 5,192,741

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
United Kingdom	8722134	Sep 21, 1987

International Family Members for US Patent 5,192,741

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	397035	⤷ Sign Up
Austria	A223488	⤷ Sign Up
Australia	2232688	⤷ Sign Up
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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