Analyzing the Scope and Claims of United States Patent 5,385,929
Introduction
United States Patent 5,385,929, titled "[(Hydroxyphenylamino) carbonyl] pyrroles," is a patent that describes a series of hydroxyphenyl compounds and their pharmaceutical applications. Here, we will delve into the scope, claims, and the broader patent landscape surrounding this invention.
Patent Overview
Publication Details
- Publication Number: US5385929A
- Authority: United States
- Prior Art Date: The patent was filed on August 12, 1993, and granted on January 31, 1995[4].
Invention Description
The patent describes hydroxyphenyl compounds of specific formulas, including their open-chain acid forms, and the methods for their preparation. These compounds are particularly useful in treating conditions such as hypercholesterolemia and atherosclerosis.
Scope of the Invention
Compounds Described
The patent details two main formulas:
- Formula I: This involves hydroxyphenyl compounds with specific substituents.
- Formula II: This is the open-chain acid form of the compounds described in Formula I[4].
These compounds are prepared through several alternative methods, including the reaction of suitably substituted N-acyl-N-alkyl amino acids with substituted hydroxyphenyl acetylenic compounds.
Pharmaceutical Applications
The invention includes pharmaceutical formulations comprising the lactone of Formula I or the heptanoic acid form of Formula II, along with their pharmaceutically acceptable salts and solvates. These formulations are used to treat mammals suffering from hypercholesterolemia by inhibiting the biosynthesis of cholesterol[4].
Claims of the Patent
Independent Claims
The patent includes several independent claims that define the scope of the invention:
- Claim 1: This claim describes the hydroxyphenyl compounds of Formula I and their open-chain acid forms.
- Claim 2: This claim covers the pharmaceutically acceptable salts and solvates of the compounds.
- Claim 3: This claim pertains to the pharmaceutical formulations containing these compounds and their salts/solvates[4].
Dependent Claims
Dependent claims further specify the compounds, their preparation methods, and the pharmaceutical formulations. For example, dependent claims might detail specific substituents, reaction conditions, or the composition of the pharmaceutical formulations.
Patent Landscape
Prior Art
The patent references several prior art patents, including U.S. Pat. No. 4,681,893 and U.S. Pat. No. 5,273,995. These prior patents describe related compounds and methods that are incorporated by reference into the current patent[4].
International Patent Family
To understand the global reach of this invention, it is essential to search international patent databases such as those provided by the European Patent Office (EPO), Japan Patent Office (JPO), and the World Intellectual Property Organization (WIPO)[1].
Current Status
The patent has expired, as indicated by its legal status. This means that the inventions described in the patent are now in the public domain and can be freely used without infringing on the original patent rights[4].
Search Tools and Resources
USPTO Resources
For a comprehensive analysis, one can use the USPTO's Patent Public Search tool, which provides enhanced access to prior art. Additionally, the Global Dossier service allows users to view the patent family for a specific application, including related applications filed at participating IP Offices[1].
International Databases
Searching international patent databases such as esp@cenet (EPO), PATENTSCOPE (WIPO), and the Japan Patent Office database can help identify similar patents or applications filed in other jurisdictions[1].
Economic and Research Implications
Patent Claims Research Dataset
The USPTO's Patent Claims Research Dataset can provide insights into the scope and trends of patent claims, including those related to pharmaceutical inventions. This dataset contains detailed information on claims from US patents granted between 1976 and 2014 and US patent applications published between 2001 and 2014[3].
Key Takeaways
- Compound Description: The patent describes specific hydroxyphenyl compounds and their open-chain acid forms.
- Pharmaceutical Applications: These compounds are used in treating hypercholesterolemia and atherosclerosis.
- Claims: The patent includes claims for the compounds, their salts/solvates, and pharmaceutical formulations.
- Prior Art: The patent references several prior art patents.
- Current Status: The patent has expired and is now in the public domain.
- Search Tools: Utilize USPTO and international patent databases for a comprehensive analysis.
FAQs
Q: What is the main subject of United States Patent 5,385,929?
A: The main subject is a series of hydroxyphenyl compounds and their pharmaceutical applications, particularly in treating hypercholesterolemia and atherosclerosis.
Q: How can I search for similar patents internationally?
A: You can use international patent databases such as esp@cenet (EPO), PATENTSCOPE (WIPO), and the Japan Patent Office database.
Q: What is the current status of the patent?
A: The patent has expired and is now in the public domain.
Q: Where can I find detailed information on patent claims for similar inventions?
A: The USPTO's Patent Claims Research Dataset provides detailed information on claims from US patents and applications.
Q: How can I access the file histories of related patent applications?
A: Use the USPTO's Global Dossier service to access the file histories of related applications from participating IP Offices.
Sources
- USPTO - Search for patents: https://www.uspto.gov/patents/search
- USA.gov - U.S. Patent and Trademark Office (USPTO): https://www.usa.gov/agencies/u-s-patent-and-trademark-office
- USPTO - Patent Claims Research Dataset: https://www.uspto.gov/ip-policy/economic-research/research-datasets/patent-claims-research-dataset
- Google Patents - US5385929A: https://patents.google.com/patent/US5385929A/en
- PubChem - Pharmaceutical compositions of amlodipine and atorvastatin: https://pubchem.ncbi.nlm.nih.gov/patent/US-2005107446-A1
