Analyzing the Scope and Claims of United States Patent 5,457,133
Introduction
United States Patent 5,457,133, titled "Pharmaceutical Compositions Containing R(+)-N-Propargyl-1-Aminoindan," is a significant patent in the field of pharmaceuticals, particularly for the treatment of Parkinson's disease and other neurological conditions. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this patent.
Background of the Invention
The patent 5,457,133, issued on October 10, 1995, pertains to pharmaceutical compositions containing R(+)-N-propargyl-1-aminoindan, commonly known as rasagiline. Rasagiline is a selective inhibitor of the B-form of the enzyme monoamine oxidase (MAO-B), which is crucial in the treatment of Parkinson's disease and other conditions involving MAO-B inhibition[5].
Scope of the Patent
The scope of the patent encompasses several key aspects:
Pharmaceutical Compositions
The patent describes various pharmaceutical compositions that include rasagiline or its pharmaceutically acceptable salts. These compositions can be formulated in different forms such as tablets, capsules, or solutions, designed for oral administration[5].
Therapeutic Uses
The primary therapeutic use of these compositions is the treatment of Parkinson's disease. However, the patent also suggests potential applications in treating other conditions where MAO-B inhibition is beneficial, such as Alzheimer's disease and other neurodegenerative disorders[5].
Synthesis and Preparation
The patent details methods for the synthesis and preparation of rasagiline and its pharmaceutical compositions. This includes specific processes for obtaining the active ingredient and formulating it into usable pharmaceutical products[5].
Claims of the Patent
The claims of the patent are critical in defining the legal boundaries of the invention.
Independent Claims
- The patent includes independent claims that describe the pharmaceutical compositions containing rasagiline.
- These claims specify the active ingredient, its concentration, and the pharmaceutical form (e.g., tablets, capsules)[5].
Dependent Claims
- Dependent claims further detail specific aspects of the independent claims, such as the dosage forms, methods of administration, and additional ingredients that can be included in the compositions[5].
Patent Landscape
Related Patents
The patent landscape around 5,457,133 includes several related patents that build upon or are related to the invention. For example:
- United States Patent Nos. 5,532,415, 5,387,612, and 5,453,446 also relate to rasagiline and its pharmaceutical applications[5].
- International publications like PCT International Application Publication No. WO 95/11016 also discuss pharmaceutical compositions containing rasagiline[5].
Global Patent Family
The patent is part of a global patent family, with corresponding patents filed in other countries. For instance, the Australian patent AU2011282716A1 discusses dispersions of rasagiline citrate, which is another form of the drug[5].
Patent Assignments and Ownership
Understanding the patent assignments and ownership is crucial for legal and commercial purposes. The Patent Assignment Search tool provided by the USPTO can be used to track changes in ownership and assignments related to this patent[1].
Search and Analysis Tools
For a comprehensive analysis, several tools and resources can be utilized:
USPTO Patent Public Search
The USPTO's Patent Public Search tool is a powerful resource for searching prior art and related patents. This tool can help in identifying similar patents and understanding the broader patent landscape[1].
Global Dossier
The Global Dossier service provides access to the file histories of related applications from participating IP Offices, which can be useful in tracking the global patent family and any office actions related to the patent[1].
Patent Claims Research Dataset
The USPTO's Patent Claims Research Dataset can provide detailed information on claims from U.S. patents, including those related to 5,457,133. This dataset can help in analyzing the scope and claims of the patent in a more quantitative manner[3].
Legal and Policy Considerations
The legal and policy environment surrounding patents is constantly evolving. For example, discussions around a potential small claims patent court highlight the ongoing efforts to streamline and improve the patent litigation process[2].
Conclusion
United States Patent 5,457,133 is a significant patent in the pharmaceutical sector, particularly for the treatment of Parkinson's disease. Understanding its scope, claims, and the broader patent landscape is essential for both legal and commercial purposes.
Key Takeaways
- Pharmaceutical Compositions: The patent covers various pharmaceutical compositions containing rasagiline.
- Therapeutic Uses: Primarily for treating Parkinson's disease and other conditions involving MAO-B inhibition.
- Synthesis and Preparation: Detailed methods for synthesizing and preparing rasagiline and its pharmaceutical compositions.
- Related Patents: Part of a larger patent family with related patents in the U.S. and internationally.
- Search and Analysis Tools: Utilize USPTO tools like Patent Public Search and Global Dossier for comprehensive analysis.
FAQs
Q: What is the primary therapeutic use of the compositions described in US Patent 5,457,133?
A: The primary therapeutic use is the treatment of Parkinson's disease through the inhibition of MAO-B.
Q: How can one search for related patents to US Patent 5,457,133?
A: Use the USPTO's Patent Public Search tool or the Global Dossier service to search for related patents and track the global patent family.
Q: What is the significance of the Patent Claims Research Dataset in analyzing this patent?
A: The dataset provides detailed information on claims from U.S. patents, allowing for a quantitative analysis of the patent's scope and claims.
Q: Are there any ongoing legal or policy discussions relevant to this patent?
A: Yes, discussions around a potential small claims patent court are ongoing, which could impact the litigation process for patents like 5,457,133.
Q: How can changes in ownership or assignments of this patent be tracked?
A: Use the Patent Assignment Search tool provided by the USPTO to track changes in ownership and assignments.
Sources
- USPTO - Search for patents: https://www.uspto.gov/patents/search
- ACUS - U.S. Patent Small Claims Court: https://www.acus.gov/research-projects/us-patent-small-claims-court
- USPTO - Patent Claims Research Dataset: https://www.uspto.gov/ip-policy/economic-research/research-datasets/patent-claims-research-dataset
- Canadian Patents Database - Patent 2851274 Summary: https://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2851274/summary.html
- Google Patents - AU2011282716A1: https://patents.google.com/patent/AU2011282716A1/en
