Details for Patent: 5,466,861

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Summary for Patent: 5,466,861

Title:	Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
Abstract:	Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and n are as defined herein. The novel compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well.
Inventor(s):	Dawson; Marcia L. (Menlo Park, CA), Cameron; James F. (Palo Alto, CA), Hobbs; Peter D. (Moss Beach, CA), Jong; Ling (Sunnyvale, CA), Pfahl; Magnus (Solana Beach, CA), Zhang; Xiao-kun (La Jolla, CA), Lehmann; Jurgen M. (Solana Beach, CA)
Assignee:	SRI International (Menlo Park, CA) La Jolla Cancer Research Foundation (La Jolla, CA)
Application Number:	07/982,305
Patent Claim Types: see list of patent claims	Compound; Composition;

Drugs Protected by US Patent 5,466,861

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