Details for Patent: 5,466,861
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Summary for Patent: 5,466,861
Title: | Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors |
Abstract: | Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and n are as defined herein. The novel compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well. |
Inventor(s): | Dawson; Marcia L. (Menlo Park, CA), Cameron; James F. (Palo Alto, CA), Hobbs; Peter D. (Moss Beach, CA), Jong; Ling (Sunnyvale, CA), Pfahl; Magnus (Solana Beach, CA), Zhang; Xiao-kun (La Jolla, CA), Lehmann; Jurgen M. (Solana Beach, CA) |
Assignee: | SRI International (Menlo Park, CA) La Jolla Cancer Research Foundation (La Jolla, CA) |
Application Number: | 07/982,305 |
Patent Claim Types: see list of patent claims | Compound; Composition; |
Drugs Protected by US Patent 5,466,861
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
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