United States Patent 5,468,743: A Detailed Analysis of Scope, Claims, and Patent Landscape
Introduction
United States Patent 5,468,743, titled "Imidazo[2,1-b]benzazepine derivatives, compositions and method of use," was granted to Janssen and is a significant patent in the pharmaceutical field. This analysis will delve into the scope and claims of the patent, as well as the broader patent landscape surrounding this invention.
Patent Overview
Publication Details
- Publication Number: US5468743A
- Authority: United States
- Prior Art Date: The patent was filed on June 11, 1993, and granted on October 17, 1995[4].
Invention Description
The patent describes novel imidazo[2,1-b][3]benzazepine derivatives, their pharmaceutically acceptable addition salts, and stereochemically isomeric forms. These compounds are characterized by a central 7-membered ring containing a nitrogen atom of a fused imidazole ring, which distinguishes them from previously known compounds. The invention highlights the favorable antiallergic activity of these compounds[4].
Scope of the Patent
Chemical Structure
The patent specifies the chemical structure of the imidazo[2,1-b][3]benzazepine derivatives, including the various substituents (R1, R2, R3, etc.) that can be attached to the core structure. These substituents include hydrogen, halo, C1-4 alkyl, and other functional groups. The patent also covers all possible stereochemically and conformationally isomeric forms of these compounds[4].
Pharmaceutical Applications
The patent outlines the pharmaceutical applications of these compounds, particularly their antiallergic activity. The invention includes compositions and methods of use for these compounds, which are intended for therapeutic purposes.
Claims of the Patent
Independent Claims
The patent includes several independent claims that define the scope of the invention. These claims cover:
- The novel imidazo[2,1-b][3]benzazepine derivatives and their pharmaceutically acceptable salts.
- The stereochemically isomeric forms of these compounds.
- Compositions containing these compounds.
- Methods of use for these compounds in therapeutic applications[4].
Dependent Claims
Dependent claims further specify the substituents and structural variations of the compounds, as well as specific methods of preparation and use.
Patent Landscape Analysis
Defining Scope and Keywords
To analyze the patent landscape surrounding US5468743A, one must first define the scope and relevant keywords. This involves identifying the technology field (in this case, pharmaceuticals and specifically antiallergic compounds) and the specific terms that best represent it[3].
Search and Organize Patents
Using databases such as the USPTO's Patent Public Search tool, the European Patent Office's esp@cenet, and the World Intellectual Property Organization's PATENTSCOPE, one can search for relevant patents based on the chosen keywords. Patents can be organized by factors like filing date, assignee, and technology subcategories[1][3].
Identify Trends and Key Players
The analysis reveals trends in patent filings within the antiallergic compound domain. Key players, such as pharmaceutical companies like Janssen, are identified as significant contributors to this field. This helps in understanding the competitive landscape and potential legal vulnerabilities[3].
Analyze Citations and Evolution
Studying how patents reference each other provides insights into the impact and development of the inventions. The Common Citation Document (CCD) application can be used to consolidate prior art cited by all participating offices for the family members of a patent application, facilitating a deeper understanding of the patent's position within the broader landscape[1].
Generate Insights for Decisions
The analysis translates into practical guidance for strategic decisions. For instance, it helps in evaluating the strength of a patent portfolio, identifying potential gaps in the market, and understanding technological trends. This information is crucial for inventors and companies looking to make informed decisions about their innovations[3].
Key Players and Competitors
Janssen
As the assignee of US5468743A, Janssen is a key player in the development of antiallergic compounds. The company's patent portfolio in this area indicates a strong focus on pharmaceutical research and development.
Other Pharmaceutical Companies
Other pharmaceutical companies, such as Pfizer, Merck, and GlaxoSmithKline, are also active in the field of antiallergic compounds. These companies have their own patent portfolios and research initiatives, contributing to the competitive landscape.
Technological Trends
Advances in Pharmaceutical Chemistry
The patent landscape analysis reveals ongoing innovations in pharmaceutical chemistry, particularly in the synthesis and application of novel compounds. There is a trend towards developing compounds with improved efficacy and reduced side effects.
Regulatory Environment
The regulatory environment plays a crucial role in the patent landscape. Changes in regulations and guidelines by bodies like the FDA can impact the development and approval of new pharmaceutical compounds.
Legal Considerations
Patent Expiration
The patent US5468743A has expired, which means that the exclusive rights to the invention are no longer in effect. This opens up opportunities for generic versions of the compounds to be developed and marketed.
Litigation and Disputes
Patent litigation and disputes are common in the pharmaceutical industry. Companies must be aware of potential legal vulnerabilities and ensure that their innovations do not infringe on existing patents.
Conclusion
Understanding the scope and claims of US5468743A, along with the broader patent landscape, is essential for navigating the complex world of pharmaceutical innovations. This analysis provides valuable insights into technological trends, key players, and legal considerations, helping inventors and companies make informed decisions about their research and development strategies.
Key Takeaways
- Patent Scope: US5468743A covers novel imidazo[2,1-b][3]benzazepine derivatives with antiallergic activity.
- Claims: The patent includes claims for the compounds, their salts, and methods of use.
- Patent Landscape: The analysis reveals trends in pharmaceutical chemistry, key players like Janssen, and the competitive landscape.
- Technological Trends: Ongoing innovations in synthesis and application of novel compounds.
- Legal Considerations: The patent has expired, and companies must be aware of potential legal vulnerabilities.
FAQs
What is the main subject of US5468743A?
The main subject of US5468743A is novel imidazo[2,1-b][3]benzazepine derivatives with antiallergic activity.
Who is the assignee of US5468743A?
The assignee of US5468743A is Janssen.
What is the current legal status of US5468743A?
The patent US5468743A has expired.
How can one conduct a patent landscape analysis for this field?
One can conduct a patent landscape analysis by defining the scope and keywords, searching and organizing patents, identifying trends and key players, analyzing citations and evolution, and generating insights for decisions[3].
What are some key resources for searching patents related to this field?
Key resources include the USPTO's Patent Public Search tool, the European Patent Office's esp@cenet, and the World Intellectual Property Organization's PATENTSCOPE[1].
Sources
- USPTO - Search for patents: https://www.uspto.gov/patents/search
- Regulations.gov - Untitled: https://downloads.regulations.gov/FDA-2011-E-0168-0008/attachment_1.pdf
- Goldstein Patent Law - How to Do Patent Landscape Analysis: https://www.goldsteinpatentlaw.com/how-to-patent-landscape-analysis/
- Google Patents - US5468743A: https://patents.google.com/patent/US5468743A/en
- PubChem - Thermoplastic resin film and its manufacturing method: https://pubchem.ncbi.nlm.nih.gov/patent/JP-7336522-B2
