Details for Patent: 5,591,762
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Summary for Patent: 5,591,762
| Title: | Benzimidazoles useful as angiotensin-11 antagonists |
| Abstract: | Disclosed herein are angiotensin-II antagonists of the formula ##STR1## wherein R.sub.1 is, other than hydrogen and, inter alia, halogen, lower alkyl or cycloalkyl; R.sub.2 is, inter alia, optionally substituted benzimidazol-2-yl, 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-2-yl, butanesultam-1-yl, imidazol-4-yl, and tetrahydobenzimidazol-2-yl; R.sub.3 is, inter alia, lower alkyl; and, R.sub.4 is an acidic group, such as carboxyl or tetrazolyl. An exemplary compound is: (a) 4'-[[2-n-propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)-benzimidazol-1-yl] methyl]-biphenyl-2-carboxylic acid. |
| Inventor(s): | Hauel; Norbert (Schemmerhofen, DE), Narr, deceased; Berthold (late of Biberach, DE), Ries; Uwe (Biberch, DE), van Meel; Jacobus C. A. (Mittelbiberach, DE), Wienen; Wolfgang (Biberach/Rissegg, DE), Entzeroth; Michael (Warthausen, DE) |
| Assignee: | Dr. Karl Thomae GmbH (Biberach an der Riss, DE) |
| Application Number: | 08/457,204 |
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Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
Drugs Protected by US Patent 5,591,762
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 5,591,762
| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| Germany | 41 03 492.9 | Feb 06, 1991 |
| Germany | 41 17 121.7 | May 25, 1991 |
| Germany | 41 37 812.1 | Nov 16, 1991 |
| Germany | 42 01 554.5 | Jan 22, 1992 |
| Germany | 42 12 250.3 | Apr 11, 1992 |
International Family Members for US Patent 5,591,762
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 0502314 | ⤷ Sign Up | 3/2011 | Austria | ⤷ Sign Up |
| European Patent Office | 0502314 | ⤷ Sign Up | CA 2002 00023 | Denmark | ⤷ Sign Up |
| European Patent Office | 0502314 | ⤷ Sign Up | SPC/GB02/037 | United Kingdom | ⤷ Sign Up |
| European Patent Office | 0502314 | ⤷ Sign Up | C300478 | Netherlands | ⤷ Sign Up |
| European Patent Office | 0502314 | ⤷ Sign Up | CA 2011 00008 | Denmark | ⤷ Sign Up |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
