Details for Patent: 5,614,560

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Summary for Patent: 5,614,560

Patent landscape, scope, and claims:

Title:	Method of preventing NMDA receptor-mediated neuronal damage
Abstract:	Disclosed is a method for reducing non-ischemic NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a compound of the formula shown in FIG. 1 (or a physiologically-acceptable salt thereof), wherein R.sub.1 includes an amino group, R.sub.2 -R.sub.17 are independently H or a short chain aliphatic group comprising 1-5 carbons, and R.sub.4 and R.sub.10 also may (independently) be a halogen or an acyl group. Also disclosed is a screen for antagonists of NMDA receptor mediated neurotoxicity which have an enhanced prospect for being clinically tolerated and selective against such neurotoxicity.
Inventor(s):	Lipton; Stuart A. (Newton, MA)
Assignee:	Children's Medical Center Corporation (Boston, MA)
Application Number:	08/419,672
Patent Claim Types: see list of patent claims	Use;
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