Details for Patent: 5,733,950
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Summary for Patent: 5,733,950
Title: | Biodegradable in-situ forming implants and methods of producing the same |
Abstract: | A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. A thermoplastic system to form said implant comprises the steps of dissolving a non-reactive polymer in biocompatible solvent to form a liquid, placing the liquid within the animal, and allowing the solvent to dissipate to produce the implant. An alternative, thermosetting system comprises mixing together effective amounts of a liquid acrylic ester terminated, biodegradable prepolymer and a curing agent, placing the liquid mixture within an animal and allowing the prepolymer to cure to form the implant. Both systems provide a syringeable, solid biodegradable delivery system by the addition of an effective level of biologically active agent to the liquid before injection into the body. |
Inventor(s): | Dunn; Richard L. (Fort Collins, CO), English; James P. (Birmingham, AL), Cowsar; Donald R. (Birmingham, AL), Vanderbilt; David P. (Birmingham, AL) |
Assignee: | Atrix Laboratories, Incorporated (Fort Collins, CO) |
Application Number: | 08/532,540 |
Patent Claim Types: see list of patent claims | Use; Device; Composition; Formulation; Delivery; | More… ↓ |
Drugs Protected by US Patent 5,733,950
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International Family Members for US Patent 5,733,950
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European Patent Office | 0436667 | ⤷ Subscribe | 91193 | Luxembourg | ⤷ Subscribe |
European Patent Office | 0436667 | ⤷ Subscribe | C300204 | Netherlands | ⤷ Subscribe |
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