Details for Patent: 5,962,016

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Summary for Patent: 5,962,016

Title:	Multivesicular liposomes utilizing neutral lipids to modify in vivo release
Abstract:	The rate of release of encapsulated active compound from a multivesicular liposomal (MVL) formulation is modified by selection of a neutral lipid component. A family of MVL formulations containing different slow:fast release neutral lipid molar ratios display different release rates depending upon the molar ratio of the fast release neutral lipid to the slow release neutral lipid in each member. Incubation in plasma or a plasma-like medium at in vivo temperatures so as to obtain a release rate curve for each allows selection from among the members of the family of a liposomal formulation with a desired rate of release in vivo.
Inventor(s):	Willis; Randall C. (Solana Beach, CA)
Assignee:	DepoTech Corporation (San Diego, CA)
Application Number:	08/974,296
Patent Claim Types: see list of patent claims	Compound; Dosage form; Use;

Drugs Protected by US Patent 5,962,016

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