Details for Patent: 6,132,766
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Summary for Patent: 6,132,766
Title: | Multivesicular liposomes with controlled release of encapsulated biologically active substances |
Abstract: | A multivesicular liposome composition containing at least one acid other than a hydrohalic acid and at least one biologically active substance, the vesicles having defined size distribution, adjustable average size, internal chamber size and number, provides a controlled release rate of the biologically active substance from the composition. A process for making the composition features addition of a non-hydrohalic acid effective to sustain and control the rate of release of an encapsulated biologically active substance from the vesicles at therapeutic levels in vivo. |
Inventor(s): | Sankaram; Mantripragada Bhima (San Diego, CA), Kim; Sinil (Solana Beach, CA) |
Assignee: | SkyePharma Inc. (San Diego, CA) |
Application Number: | 09/045,236 |
Patent Claim Types: see list of patent claims | Use; Dosage form; Device; |
Drugs Protected by US Patent 6,132,766
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International Family Members for US Patent 6,132,766
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