Details for Patent: 6,399,632
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Summary for Patent: 6,399,632
Title: | Method of providing an antihistaminic effect in a hepatically impaired patient |
Abstract: | The present invention relates to a method of providing an antihistaminic effect in a hepatically impaired patient in need thereof comprising administering to said patient an effective antihistaminic amount of a compound of the formula ##STR1## wherein R.sub.1 is hydrogen or hydroxy; R.sub.2 is hydrogen; or R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ; n is an integer of from 1 to 5; R.sub.3 is --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; each of A and B is hydrogen or hydroxy with the proviso that at least one of A or B is hydrogen; or a pharmaceutically acceptable salt and individual isomers thereof. |
Inventor(s): | Woodward; James K. (Cincinnati, OH), Okerholm; Richard A. (West Chester, OH), Eller; Mark G. (Overland Park, KS), McNutt; Bruce E. (Olathe, KS) |
Assignee: | Merrell Pharmaceuticals Inc. (Bridgewater, NJ) |
Application Number: | 09/663,343 |
Patent Claim Types: see list of patent claims | Use; Composition; |
Drugs Protected by US Patent 6,399,632
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International Family Members for US Patent 6,399,632
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