Details for Patent: 6,455,499

Summary for Patent: 6,455,499

Title:	Methods for treating disorders associated with LHRH activity
Abstract:	Methods of treating a subject having a disorder associated with LHRH activity are disclosed.
Inventor(s):	Roeske; Roger W. (Indianapolis, IN)
Assignee:	Indiana University Foundation (Bloomington, IN)
Application Number:	09/256,599
Patent Claim Types: see list of patent claims	Use;

United States Patent 6,455,499: A Detailed Analysis of Scope, Claims, and Patent Landscape

Introduction

United States Patent 6,455,499, titled "Methods for Treating Disorders Associated with Lhrh," is a significant patent in the biomedical research field, particularly in the area of hormone-related therapies. This patent, assigned to Indiana University Research and Technology Corp, involves innovative methods for treating disorders associated with Luteinizing Hormone-Releasing Hormone (LHRH). Here, we will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Background and Invention Overview

The patent, filed on February 23, 1999, and granted on September 24, 2002, describes methods for treating various disorders related to LHRH. LHRH is a hormone that plays a crucial role in the regulation of the reproductive system. The invention involves the use of specific peptides and analogs that can modulate LHRH activity, thereby treating conditions such as prostate cancer, precocious puberty, and endometriosis[2].

Scope of the Patent

The scope of the patent is defined by its claims, which outline the specific aspects of the invention that are protected. Here are some key aspects of the scope:

Claims Analysis

The patent includes multiple claims that cover different aspects of the invention:

• Independent Claims: These claims define the core of the invention, such as the specific peptides and their use in treating LHRH-related disorders.
• Dependent Claims: These claims build upon the independent claims and provide additional details or variations of the invention, such as different dosages or administration methods[2].

Claim Coverage Matrix

To understand the full extent of the patent's protection, a Claim Coverage Matrix can be used. This matrix categorizes the patents and claims by scope concepts, allowing for a comprehensive analysis of the patent landscape. For example, the matrix might categorize claims based on the type of peptide, the method of administration, or the specific disorder being treated[5].

Patent Claims and Scope Concepts

The claims in this patent can be categorized into several scope concepts:

Peptide Composition

Claims related to the specific composition of the peptides used in the treatment. This includes the amino acid sequence and any modifications to the peptide.

Method of Administration

Claims covering the different methods by which the peptides can be administered, such as injection, oral administration, or topical application.

Therapeutic Uses

Claims specifying the various disorders that can be treated using the peptides, including prostate cancer, precocious puberty, and endometriosis.

Patent Landscape

Understanding the patent landscape is crucial for assessing the competitive environment and potential opportunities or gaps.

Related Patents and Continuations

The patent landscape includes other patents related to LHRH and peptide therapies. For instance, patents that are continuations of the parent patent or those that have similar scope concepts need to be considered. The USPTO Public PAIR database can be used to identify patent continuation histories and related patents[1].

Public Funding and Government Interest

This patent is notable for its public funding. The invention was made with government support under a grant from the National Institutes of Health (NIH). This is disclosed in the patent and highlights the role of public funding in biomedical research[1].

Global Patent Search and International Protection

To fully understand the patent landscape, it is essential to conduct a global patent search. Tools like the Patent Public Search, Global Dossier, and databases from international intellectual property offices (such as the European Patent Office, Japan Patent Office, and World Intellectual Property Organization) can be used to identify similar patents filed in other countries[4].

Patent Analytics and Claim Charts

Patent analytics tools, such as those provided by Schwegman, can help in analyzing the claims and scope concepts of this patent. Claim charts generated by these tools can be reviewed by technical experts to determine the applicability of the scope concepts to target products or methods. This helps in identifying gaps in current coverage and highlighting future design opportunities[5].

Public and Private Investments

The development of this patent is an example of how public and private investments can collaborate in biomedical research. Public funding from agencies like the NIH can support the initial research, while private entities can further develop and commercialize the inventions[1].

Key Takeaways

• Scope and Claims: The patent covers specific peptides and methods for treating LHRH-related disorders, with claims categorized by peptide composition, method of administration, and therapeutic uses.
• Patent Landscape: The landscape includes related patents, continuations, and global filings, with public funding playing a significant role.
• Patent Analytics: Tools like Claim Coverage Matrix and claim charts are essential for analyzing the patent's protection and identifying gaps or opportunities.
• Global Protection: Conducting a global patent search is crucial for understanding the international protection of the invention.

FAQs

What is the main subject of United States Patent 6,455,499?

The main subject of this patent is methods for treating disorders associated with Luteinizing Hormone-Releasing Hormone (LHRH) using specific peptides and analogs.

Who is the assignee of this patent?

The assignee of this patent is Indiana University Research and Technology Corp.

What role did public funding play in the development of this patent?

The invention was made with government support under a grant from the National Institutes of Health (NIH).

How can the scope and claims of this patent be analyzed?

The scope and claims can be analyzed using a Claim Coverage Matrix and claim charts, which categorize the patents by scope concepts and help in identifying gaps or opportunities.

What tools can be used for conducting a global patent search related to this invention?

Tools such as the Patent Public Search, Global Dossier, and databases from international intellectual property offices like the European Patent Office, Japan Patent Office, and World Intellectual Property Organization can be used.

Sources

1. Public and private investments in biomedical research - American Economic Association
2. US-6455499-B1 - Therapeutic Peptides - Unified Patents
3. Patent Claims Research Dataset - USPTO
4. Search for patents - USPTO - USPTO
5. Patent Analytics - Schwegman, Lundberg & Woessner, P.A.

Drugs Protected by US Patent 6,455,499

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate