Details for Patent: 6,465,463
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Summary for Patent: 6,465,463
Title: | Methods of treating and preventing congestive heart failure with hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate |
Abstract: | The present invention provides methods or treating and preventing mortality associated with heart failure in an African American patient with hypertension and improving oxygen consumption, quality of life and exercise tolerance by administering a therapeutically effective amount of at least one hydralazine compound and at least one of isosorbide dinitrate and isosorbide mononitrate, and, optionally, one or more compounds, such as, for example, a digitalis, a diuretic compound, or a compound used to treat cardiovascular diseases. In the present invention, the hydralazine compound is preferably hydralazine or a pharmaceutically acceptable salt thereof. Preferred methods of the invention comprise administering hydralazine or a pharmaceutically acceptable salt thereof and isosorbide dinitrate. |
Inventor(s): | Cohn; Jay N. (Minneapolis, MN), Carson; Peter (Chevy Chase, MD) |
Assignee: | NitroMed, Inc. (Bedford, MA) |
Application Number: | 09/658,261 |
Patent Claim Types: see list of patent claims | Use; Compound; Composition; Delivery; Dosage form; | More… ↓ |
Drugs Protected by US Patent 6,465,463
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International Family Members for US Patent 6,465,463
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Canada | 2383974 | ⤷ Subscribe | |||
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World Intellectual Property Organization (WIPO) | 0117528 | ⤷ Subscribe | |||
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