Details for Patent: 6,992,218
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Summary for Patent: 6,992,218
Title: | Method for obtaining aqueous formulations of oxidation-sensitive active principles |
Abstract: | A method for obtaining aqueous formulations with easily oxidizable active principles, notably phenols, stable over a prolonged period, comprising subjecting them to extreme deoxygenation by bubbling with an inert gas and/or placing wider vaccum, protecting them against possible resorption of oxygen by keeping them under an inert gas atmosphere, by filling, under inert gas, into bottles previously cleared of air by insufflation with inert gas, then subjecting them, while stoppering, to low pressure as obtained in the bottle, of 65,000 Pa maximum, to obtain aqueous solutions having a residual oxygen concentration in the solution below 2 ppm, and preferably of the order of 1 ppm and even 0.5 ppm useful as injectable preparations having an oxygen concentration in the solution below 2 ppm. |
Inventor(s): | Dietlin; Francois (La Vesinet, FR), Fredj; Daniele (Gif sur Yvette, FR) |
Assignee: | Pharmatop SCR (FR) |
Application Number: | 10/332,060 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 6,992,218 |
Patent Claim Types: see list of patent claims | Formulation; Process; Use; |
Drugs Protected by US Patent 6,992,218
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 6,992,218
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
France | 00 07231 | Jun 06, 2000 |
France | 00 07231 | Jun 6, 2000 |
PCT Information | |||
PCT Filed | June 06, 2001 | PCT Application Number: | PCT/FR01/01749 |
PCT Publication Date: | December 13, 2001 | PCT Publication Number: | WO01/93830 |
International Family Members for US Patent 6,992,218
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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African Regional IP Organization (ARIPO) | 1880 | ⤷ Sign Up | |||
Australia | 6612001 | ⤷ Sign Up | |||
Canada | 2415403 | ⤷ Sign Up | |||
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