Details for Patent: 7,351,401
✉ Email this page to a colleague
Summary for Patent: 7,351,401
Title: | Thioflavin derivatives for use in the antemortem diagnosis of Alzheimers disease and in vivo imaging and prevention of amyloid deposition |
Abstract: | This invention relates to novel thioflavin derivatives, methods of using the derivatives in, for example, in vivo imaging of patients having neuritic plaques, pharmaceutical compositions comprising the thioflavin derivatives and method of synthesizing the compounds. The compounds find particular use in the diagnosis and treatment of patients having diseases where accumulation of neuritic plaques are prevalent. The disease states or maladies include but are not limited to Alzheimer's Disease, familial Alzheimer's Disease, Down's Syndrome and homozygotes for the apolipoprotein E4 allele. |
Inventor(s): | Klunk; William E. (Pittsburgh, PA), Mathis, Jr.; Chester A. (Pittsburgh, PA), Wang; Yanming (Imperial, PA) |
Assignee: | University of Pittsburgh (Pittsburgh, PA) |
Application Number: | 10/859,600 |
Patent Claim Types: see list of patent claims | Compound; Use; Composition; Formulation; |
Drugs Protected by US Patent 7,351,401
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 7,351,401
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
European Patent Office | 1611115 | ⤷ Sign Up | CA 2015 00009 | Denmark | ⤷ Sign Up |
European Patent Office | 1611115 | ⤷ Sign Up | C300724 | Netherlands | ⤷ Sign Up |
European Patent Office | 1611115 | ⤷ Sign Up | 15C0005 | France | ⤷ Sign Up |
European Patent Office | 1611115 | ⤷ Sign Up | C20150004 00139 | Estonia | ⤷ Sign Up |
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |