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Last Updated: December 22, 2024

Details for Patent: 7,425,637


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Summary for Patent: 7,425,637
Patent landscape, scope, and claims:
Title:N3 alkylated benzimidazole derivatives as MEK inhibitors
Abstract: Disclosed are compounds of the Formula I ##STR00001## and pharmaceutically acceptable salts and prodrugs thereof, wherein W, R.sup.1, R.sup.2, R.sup.7, R.sup.8, R.sup.9 and R.sup.10 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed is a method of using such compounds in the treatment of hyperproliferative diseases in mammals, and pharmaceutical compositions containing such compounds.
Inventor(s): Wallace; Eli M. (Lyons, CO), Lyssikatos; Joseph P. (Superior, CO), Marlow; Allison L. (Boulder, CO), Hurley; T. Brian (Boulder, CO)
Assignee: Array BioPharma Inc. (Boulder, CO)
Application Number:11/061,336
Patent Claim Types:
see list of patent claims
Compound;

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Drugs Protected by US Patent 7,425,637

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Astrazeneca KOSELUGO selumetinib sulfate CAPSULE;ORAL 213756-001 Apr 10, 2020 RX Yes No ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
Astrazeneca KOSELUGO selumetinib sulfate CAPSULE;ORAL 213756-002 Apr 10, 2020 RX Yes Yes ⤷  Subscribe ⤷  Subscribe Y ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,425,637

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1482932 ⤷  Subscribe PA2019007 Lithuania ⤷  Subscribe
European Patent Office 1482932 ⤷  Subscribe LUC00100 Luxembourg ⤷  Subscribe
European Patent Office 1482932 ⤷  Subscribe 300974 Netherlands ⤷  Subscribe
European Patent Office 1482932 ⤷  Subscribe 2019C/510 Belgium ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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