Details for Patent: 8,168,663

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Summary for Patent: 8,168,663

Title:	Pharmaceutically acceptable salt of 6-carboxy-2-(3,5 dichlorophenyl)-benzoxazole, and a pharmaceutical composition comprising the salt thereof
Abstract:	Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed.
Inventor(s):	Kelly; Jeffery W. (La Jolla, CA), Powers; Evan T. (La Jolla, CA), Razavi; Hossein (Danbury, CT)
Assignee:	The Scripps Research Institute (La Jolla, CA)
Application Number:	12/481,527
Patent Claim Types: see list of patent claims	Composition; Compound;

Drugs Protected by US Patent 8,168,663

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