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Last Updated: December 25, 2024

Details for Patent: 8,629,171


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Summary for Patent: 8,629,171
Title:Crystalline form of methyl ((1S)-1-((25)-2-(5-(4'-(2-((25)-1((2S)-2-((methoxycarbonyl)amino)-3-methy- lbutanoyl)-2-pyrrolidinyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2-me- thylpropyl)carbamate dihydrochloride salt
Abstract: The present disclosure generally relates to a crystalline form of methyl ((1S)-1-(((2S)-2-(5-(4'-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-met- hylbutanoyl)-2-pyrrolidinyl)-1H-imidazol-5-yl)-4-biphenylyl)-1H-imidazol-2- -yl)-1-pyrrolidinyl)carbonyl)-2-methylpropyl)carbamate dihydrochloride salt. The present disclosure also generally relates to a pharmaceutical composition comprising a crystalline form, as well of methods of using a crystalline form in the treatment of Hepatitis C and methods for obtaining such crystalline form.
Inventor(s): Kim; Soojin (Demarest, NJ), Gao; Qi (Wallingford, CT), Yang; Fukang (Madison, CT)
Assignee: Bristol-Myers Squibb Company (Princeton, NJ)
Application Number:12/175,104
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent 8,629,171

Introduction

Understanding the scope and claims of a patent is crucial for determining its validity, enforceability, and the potential for innovation or litigation. This article will delve into the specifics of United States Patent 8,629,171, exploring its claims, scope, and the broader patent landscape.

Overview of the Patent

United States Patent 8,629,171, titled "(1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2...," is a patent that involves chemical compounds, specifically focusing on a class of imidazolyl-pyrrolidinyl carbonyl derivatives. Here, we will examine the key elements of this patent.

Patent Claims

Independent Claims

The independent claims of a patent are the broadest claims that define the invention. For Patent 8,629,171, these claims typically outline the core structure and functionality of the chemical compounds. Independent claims are critical because they set the boundaries of what is considered novel and non-obvious, which are key criteria for patentability[3].

Dependent Claims

Dependent claims build upon the independent claims, providing more specific details about the invention. These claims often narrow down the scope by adding additional limitations or features. In the case of Patent 8,629,171, dependent claims might specify particular substituents, functional groups, or conditions under which the compounds are synthesized or used.

Patent Scope

Metrics for Measuring Scope

The scope of a patent can be measured using various metrics, such as independent claim length and independent claim count. Research has shown that narrower claims, as indicated by shorter lengths and fewer counts, are associated with a higher probability of grant and a shorter examination process[3].

Novelty and Non-Obviousness

The scope of Patent 8,629,171 must comply with the statutory requirements of novelty and non-obviousness under 35 U.S.C. § 102 and § 103, respectively. This means the invention must be new and not obvious to a person of ordinary skill in the relevant field.

Examination Process

Patent Examination Data System (PEDS)

The examination process for Patent 8,629,171 would have involved the use of the Patent Examination Data System (PEDS), which allows public users to search, view, and download bibliographic data for patent applications. This system helps in understanding the timeline and stages of the patent examination process[1].

Time Allotted for Examination

The time allotted for examining patents can significantly impact the quality and scope of the claims. The USPTO has analyzed and adjusted the time needed for thorough patent examinations, particularly in complex technology areas, to ensure that examiners have sufficient time to evaluate the novelty and non-obviousness of the invention[4].

International Patent Landscape

Global Dossier

For patents like 8,629,171, the Global Dossier service provided by the USPTO allows users to view the patent family, including related applications filed at participating IP Offices. This helps in understanding the global reach and relatedness of the patent[1].

Searchable Databases

To determine if similar inventions have been patented abroad, one can use searchable databases from international intellectual property offices such as the European Patent Office (EPO), Japan Patent Office (JPO), and the World Intellectual Property Organization (WIPO)[1].

Quality Metrics and Compliance

Definition of Patent Quality

The USPTO defines a quality patent as one that is correctly issued in compliance with all the requirements of Title 35 and relevant case law at the time of issuance. This definition is crucial for evaluating the quality of Patent 8,629,171[4].

Correctness Measures

The USPTO uses correctness measures and quantifiable compliance targets to ensure that patents meet statutory requirements. These measures include compliance rates for 35 U.S.C. § 101, § 112, § 102, and § 103, which are calculated from reviews of randomly-selected Office actions[4].

Public Access and Resources

Patent Public Search

The Patent Public Search tool is a powerful resource for searching prior art related to Patent 8,629,171. This tool provides enhanced access to prior art through modern interfaces, improving the overall patent searching process[1].

Patent and Trademark Resource Centers (PTRCs)

Local PTRCs offer training in patent search techniques and maintain local search resources, which can be invaluable for understanding the scope and claims of a patent like 8,629,171[1].

Key Takeaways

  • Claims Analysis: Independent and dependent claims define the scope of the patent, with narrower claims generally associated with a higher probability of grant.
  • Examination Process: The examination process involves thorough evaluation of novelty and non-obviousness, with adjustments in examination time to ensure quality.
  • International Landscape: Global Dossier and international searchable databases help in understanding the global reach of the patent.
  • Quality Metrics: The USPTO's definition of patent quality and correctness measures ensure compliance with statutory requirements.
  • Public Resources: Tools like Patent Public Search and PTRCs are essential for conducting thorough searches and understanding the patent landscape.

FAQs

Q: What are the key metrics for measuring the scope of a patent? A: Independent claim length and independent claim count are simple yet effective metrics for measuring patent scope[3].

Q: How does the USPTO define patent quality? A: The USPTO defines a quality patent as one that is correctly issued in compliance with all the requirements of Title 35 and relevant case law at the time of issuance[4].

Q: What resources are available for searching prior art related to a patent? A: Resources include the Patent Public Search tool, Global Dossier, and searchable databases from international intellectual property offices[1].

Q: Why is the examination time important for patent quality? A: The examination time is crucial because it ensures that examiners have sufficient time to evaluate the novelty and non-obviousness of the invention, impacting the quality of the patent[4].

Q: How can one access the file histories of related patent applications? A: The Global Dossier service provides access to the file histories of related applications from participating IP Offices[1].

Sources

  1. USPTO - Search for patents: https://www.uspto.gov/patents/search
  2. USA.gov - U.S. Patent and Trademark Office (USPTO): https://www.usa.gov/agencies/u-s-patent-and-trademark-office
  3. SSRN - Patent Claims and Patent Scope: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2844964
  4. GAO - Intellectual Property: Patent Office Should Define Quality, Reassess ...: https://www.gao.gov/products/gao-16-490
  5. PubChem - 1H-imidazol-2-yl)-1-pyrrolidinyl)carbonyl)-2 ...: https://pubchem.ncbi.nlm.nih.gov/patent/US-8629171-B2

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Drugs Protected by US Patent 8,629,171

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bristol-myers Squibb DAKLINZA daclatasvir dihydrochloride TABLET;ORAL 206843-001 Jul 24, 2015 DISCN Yes No ⤷  Subscribe ⤷  Subscribe Y Y METHOD OF INHIBITING HEPATITIS C VIRUS ⤷  Subscribe
Bristol-myers Squibb DAKLINZA daclatasvir dihydrochloride TABLET;ORAL 206843-002 Jul 24, 2015 DISCN Yes No ⤷  Subscribe ⤷  Subscribe Y Y METHOD OF INHIBITING HEPATITIS C VIRUS ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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