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Last Updated: March 14, 2025

Details for Patent: RE45128


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Summary for Patent: RE45128
Title:Cephalotaxane derivatives and their processes of preparation and purification
Abstract: The present invention concerns a new general process for asymmetric hemisynthesis of harringtonines and their analogs, that are alkaloids used in chemotherapy. This process comprises direct esterification of a natural cephalotaxine with an acylating compound constituted of a side chain precursor which backbone and functionalization are entirely preformed. The invention also concerns a natural, synthetic or semi-synthetic harringtonines including their tautomeric forms and their salts of the following formula: ##STR00001## wherein n=2 (i.e. harringtonine) or n=3 (i.e. homoharringtonine), in which the total content of impurities, possibly including enantiomeric forms, is lower than 1%, and/or the content of the major impurity is lower than 0.9%, and/or the chromatographic assay exhibits a harringtonines content higher than 97.5%.
Inventor(s): Robin; Jean-Pierre (Geneva, CH), Blanchard; Julie (Puyricard, FR), Marie; Jean-Pierre (Sevres, FR), Radosevic; Nina (Geneva, CH)
Assignee: IVAX International GmbH (Rapperswil, CH)
Application Number:13/661,677
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent RE45128: A Comprehensive Guide

Introduction

When analyzing a patent, particularly one like the United States Patent RE45128, it is crucial to understand the scope, claims, and the broader patent landscape. This article will delve into the key aspects of patent analysis, using RE45128 as a case study.

Understanding Patent Scope and Claims

What are Patent Claims?

Patent claims define the scope of protection granted by a patent. They are the legal boundaries that distinguish the invention from prior art and other existing technologies[3].

Importance of Claim Construction

Claim construction is a critical step in patent litigation, as it determines the meaning and scope of the claims. This process involves interpreting the language of the claims in the context of the specification and the prosecution history of the patent[2].

The Patent Claims Research Dataset

The USPTO's Patent Claims Research Dataset provides valuable insights into patent claims. This dataset includes detailed information on claims from U.S. patents granted between 1976 and 2014 and U.S. patent applications published between 2001 and 2014. It helps in understanding claim-level statistics and document-level statistics, which can be applied to analyze the scope of any patent, including RE45128[3].

Analyzing the Patent Landscape

Global Dossier and International Search

To understand the global patent landscape, tools like the Global Dossier are essential. This service provides access to the file histories of related applications from participating IP Offices, allowing users to see the patent family for a specific application and related citation data[1].

Searching International Patent Offices

Searching international patent databases, such as those provided by the European Patent Office (EPO), Japan Patent Office (JPO), and World Intellectual Property Organization (WIPO), helps in identifying whether similar inventions have been patented abroad[1].

Patent RE45128: A Case Study

Background

United States Patent RE45128 is a reissue patent, which means it is a re-examination of an original patent with potential changes to the claims. Understanding the original patent and the reasons for reissue is crucial.

Claim Analysis

To analyze the claims of RE45128, one must:

  • Identify Independent and Dependent Claims: Independent claims stand alone and define the invention, while dependent claims refer back to and further limit the independent claims.
  • Understand Claim Dependencies: The dependency relationship between claims can affect the scope of protection. Tools like the Patent Claims Research Dataset can help in parsing these dependencies[3].

Scope of Protection

The scope of protection for RE45128 is defined by its claims. Here, it is important to consider:

  • Literal Infringement: Whether another product or process literally infringes the claims.
  • Doctrine of Equivalents: Whether another product or process is equivalent to what is claimed, even if it does not literally infringe[5].

Defenses and Validity

Presumption of Validity

A patent is presumed valid under 35 USC 282. However, this presumption can be challenged through various defenses such as prior art, obviousness, and the on-sale bar[5].

On-Sale Bar

The on-sale bar, as seen in cases like Sunoco Partners Marketing & Terminals L.P. v. U.S. Venture, Inc., can render a patent invalid if the invention was on sale more than one year before the patent application was filed. The experimental-use doctrine can sometimes exempt sales from this bar, but it must be proven that the sale was primarily for experimental purposes[2].

Tools and Resources for Patent Search

Patent Public Search

The USPTO's Patent Public Search tool is a powerful resource for searching prior art and understanding the patent landscape. It provides enhanced access to prior art and modern interfaces for searching[1].

Patent and Trademark Resource Centers (PTRCs)

Local PTRCs offer training in patent search techniques and maintain local search resources, which can be invaluable for thorough patent analysis[1].

International Patent Databases

Access to international patent databases, such as PATENTSCOPE by WIPO, esp@cenet by EPO, and databases from other countries, is crucial for a comprehensive analysis. These databases provide full-text searches and machine translations, helping to identify global patent filings related to the invention[1].

Key Takeaways

  • Understand Claim Construction: Accurate interpretation of patent claims is critical for determining the scope of protection.
  • Use Comprehensive Search Tools: Utilize tools like the Patent Public Search, Global Dossier, and international patent databases to understand the broader patent landscape.
  • Analyze Defenses and Validity: Consider defenses such as the on-sale bar and the experimental-use doctrine when evaluating the validity of a patent.
  • Leverage Datasets: The Patent Claims Research Dataset can provide detailed insights into claim-level and document-level statistics.

FAQs

Q: What is the significance of claim construction in patent litigation?

A: Claim construction determines the meaning and scope of the claims, which is crucial for patent litigation as it defines the legal boundaries of the invention.

Q: How can I search for prior art related to a specific patent?

A: Use tools like the USPTO's Patent Public Search, Global Dossier, and international patent databases such as PATENTSCOPE and esp@cenet.

Q: What is the on-sale bar, and how can it affect patent validity?

A: The on-sale bar renders a patent invalid if the invention was on sale more than one year before the patent application was filed. However, sales primarily for experimental purposes may be exempt.

Q: How do I access and analyze the claims of a reissue patent like RE45128?

A: Analyze the original patent and the reissue application to understand changes to the claims. Use tools like the Patent Claims Research Dataset to parse claim dependencies and statistics.

Q: What is the role of the experimental-use doctrine in patent law?

A: The experimental-use doctrine can exempt sales from the on-sale bar if it is proven that the sale was primarily for experimental purposes to determine whether the invention works as intended.

Sources

  1. USPTO - Search for patents: https://www.uspto.gov/patents/search
  2. Sunoco Partners Marketing & Terminals L.P. v. U.S. Venture, Inc.: https://cafc.uscourts.gov/opinions-orders/20-1640.OPINION.4-29-2022_1943607.pdf
  3. Patent Claims Research Dataset - USPTO: https://www.uspto.gov/ip-policy/economic-research/research-datasets/patent-claims-research-dataset
  4. Request for Comments on USPTO Initiatives: https://unblock.federalregister.gov
  5. 35 USC 282: Presumption of validity; defenses: https://uscode.house.gov/view.xhtml?req=granuleid%3AUSC-1994-title35-section282&num=0&edition=1994

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Drugs Protected by US Patent RE45128

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Patented / Exclusive UseSubmissiondate
No data available in table
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Patented / Exclusive Use>Submissiondate
Showing 0 to 0 of 0 entries

Foreign Priority and PCT Information for Patent: RE45128

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
France98 03492Mar 20, 1998

International Family Members for US Patent RE45128

CountryPatent NumberEstimated ExpirationSupplementary Protection CertificateSPC CountrySPC Expiration
Australia 2002304338 ⤷  Try for Free
Australia 3270699 ⤷  Try for Free
Austria 289312 ⤷  Try for Free
Canada 2324895 ⤷  Try for Free
Canada 2441428 ⤷  Try for Free
China 1220692 ⤷  Try for Free
China 1300289 ⤷  Try for Free
>Country>Patent Number>Estimated Expiration>Supplementary Protection Certificate>SPC Country>SPC Expiration
Showing 1 to 7 of 7 entries

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.