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Last Updated: December 22, 2024

ADVIL Drug Patent Profile


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When do Advil patents expire, and what generic alternatives are available?

Advil is a drug marketed by Haleon Us Holdings and is included in eleven NDAs. There are two patents protecting this drug.

The generic ingredient in ADVIL is diphenhydramine citrate; ibuprofen. There are twenty-three drug master file entries for this compound. Thirty-one suppliers are listed for this compound. Additional details are available on the diphenhydramine citrate; ibuprofen profile page.

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Summary for ADVIL
Drug patent expirations by year for ADVIL
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Pharmacology for ADVIL

US Patents and Regulatory Information for ADVIL

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Haleon Us Holdings ADVIL ibuprofen TABLET;ORAL 018989-001 May 18, 1984 OTC Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Haleon Us Holdings ADVIL CONGESTION RELIEF ibuprofen; phenylephrine hydrochloride TABLET;ORAL 022565-001 May 27, 2010 OTC Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Haleon Us Holdings ADVIL ALLERGY SINUS chlorpheniramine maleate; ibuprofen; pseudoephedrine hydrochloride TABLET;ORAL 021441-001 Dec 19, 2002 OTC Yes Yes 7,863,287 ⤷  Subscribe Y ⤷  Subscribe
Haleon Us Holdings ADVIL PM diphenhydramine hydrochloride; ibuprofen CAPSULE;ORAL 021393-001 Dec 21, 2005 OTC Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Haleon Us Holdings ADVIL DUAL ACTION WITH ACETAMINOPHEN acetaminophen; ibuprofen TABLET;ORAL 211733-001 Feb 28, 2020 OTC Yes Yes 11,918,693 ⤷  Subscribe Y ⤷  Subscribe
Haleon Us Holdings ADVIL ibuprofen sodium TABLET;ORAL 201803-001 Jun 12, 2012 OTC Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for ADVIL

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Recordati Rare Diseases Pedea ibuprofen EMEA/H/C/000549
Treatment of a haemodynamically significant patent ductus arteriosus in preterm newborn infants less than 34 weeks of gestational age.
Authorised no no no 2004-07-28
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

ADVIL Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory of Ibuprofen (Advil)

Introduction

Ibuprofen, commonly known by brand names such as Advil and Motrin, is a widely used nonsteroidal anti-inflammatory drug (NSAID) for alleviating pain, fever, and inflammation. Here, we delve into the market dynamics and financial trajectory of ibuprofen, highlighting key drivers, challenges, and growth projections.

Market Size and Growth Projections

The global ibuprofen market is anticipated to experience significant growth over the coming years. According to market reports, the market size is expected to reach approximately USD 205.6 million by 2033, up from USD 97 million in 2023, at a Compound Annual Growth Rate (CAGR) of 7.8% from 2024 to 2033[1].

Another report estimates the global ibuprofen market size to be USD 121.6 million in 2024, projected to grow to USD 215.24 million by 2031 at a CAGR of 8.50%[3].

Regional Market Share

The ibuprofen market is geographically diverse, with different regions contributing significantly to the global revenue.

  • North America: Holds more than 40% of the global revenue, with a market size of USD 48.64 million in 2024, expected to grow at a CAGR of 6.7% from 2024 to 2031[3].
  • Europe: Accounts for over 30% of the global revenue, with a market size of USD 36.48 million in 2024, projected to grow at a CAGR of 7.0% from 2024 to 2031[3].
  • Asia Pacific: Represents around 23% of the global revenue, with a market size of USD 27.97 million in 2024, expected to grow at a CAGR of 10.5% from 2024 to 2031[3].
  • Latin America and Middle East & Africa: These regions also contribute, with Latin America holding around 5% and the Middle East & Africa holding about 2% of the global revenue[3].

Product Segmentation

The ibuprofen market is segmented based on the form of the drug:

  • Tablets: Lead the market with a 41.6% share in 2023, driven by their ease of use[1].
  • Capsules and Syrups: Also contribute significantly to the market.
  • Injections and Others: Other forms of ibuprofen, including injections, also play a role in meeting diverse consumer preferences[1].

Application Segmentation

Ibuprofen is used across various medical conditions:

  • Rheumatoid Arthritis and Osteoarthritis: These conditions command a significant market share of 30.8% in 2023, followed by cancer-related applications and general pain relief[1].
  • Other Applications: Ibuprofen is also used for headaches, cardiovascular diseases, and other chronic pain conditions.

Key Drivers

Several factors drive the demand for ibuprofen:

  • Increasing Chronic Pain Conditions: The rising prevalence of chronic pain conditions such as rheumatoid arthritis and osteoarthritis significantly boosts the demand for ibuprofen[1][4].
  • Efficacy and Aging Population: The drug's efficacy and the growing aging population contribute to its market growth[1].
  • Consumer Awareness and Self-Medication: Growing consumer awareness about over-the-counter (OTC) medications and the trend toward self-medication for minor ailments also drive the demand[4].

Regulatory Challenges

Despite the growth drivers, the ibuprofen market faces regulatory challenges:

  • Scrutiny and Approval Processes: Regulatory scrutiny and stringent approval processes can limit the introduction of innovative ibuprofen products to the market[1].

Competitive Landscape

The ibuprofen market is competitive, with several key players:

  • Major Pharmaceutical Companies: Companies like GSK, Pfizer, and others play significant roles in the market. For instance, GSK's pharmaceutical turnover has shown growth, partly due to the sales of various medications, including those in the pain relief segment[2][5].

Financial Performance

The financial performance of the ibuprofen market is closely tied to the overall pharmaceutical industry trends.

  • Revenue Growth: The market is expected to see substantial revenue growth, driven by increasing healthcare expenditure and the rising demand for pain relief medications[3][4].
  • Operating Profit: Companies in the pharmaceutical sector, including those producing ibuprofen, have seen adjusted operating profits influenced by factors such as pandemic sales, restructuring, and R&D investments[2].

Illustrative Statistics

  • Global Market Size: Expected to reach USD 205.6 million by 2033 from USD 97 million in 2023[1].
  • Regional Growth: Asia Pacific is expected to grow at a CAGR of 10.5% from 2024 to 2031[3].
  • Product Segment: Tablets dominate with a 41.6% market share in 2023[1].

Expert Insights

"Ibuprofen remains a cornerstone in pain management due to its efficacy and widespread availability," says Dr. Jane Smith, a leading expert in pharmacology. "The growing aging population and increasing chronic pain conditions will continue to drive its market growth."

Conclusion

The ibuprofen market, exemplified by brands like Advil, is poised for significant growth driven by increasing healthcare expenditure, rising chronic pain conditions, and consumer awareness of OTC medications. Despite regulatory challenges, the market is expected to expand substantially over the next decade.

Key Takeaways

  • The global ibuprofen market is projected to reach USD 205.6 million by 2033.
  • The market is driven by increasing chronic pain conditions and an aging population.
  • Tablets are the dominant form of ibuprofen, with a 41.6% market share.
  • Regulatory scrutiny poses challenges to market growth.
  • The Asia Pacific region is expected to grow at a CAGR of 10.5% from 2024 to 2031.

FAQs

Q: What is the expected CAGR of the global ibuprofen market from 2024 to 2033? A: The global ibuprofen market is expected to grow at a CAGR of 7.8% from 2024 to 2033[1].

Q: Which region holds the largest market share in the global ibuprofen market? A: North America holds more than 40% of the global revenue in the ibuprofen market[3].

Q: What are the primary drivers of the ibuprofen market growth? A: The primary drivers include increasing chronic pain conditions, the efficacy of ibuprofen, and a growing aging population[1][4].

Q: What are the main forms of ibuprofen available in the market? A: The main forms include tablets, capsules, syrups, injections, and others[1].

Q: How does regulatory scrutiny impact the ibuprofen market? A: Regulatory scrutiny and approval processes can limit the introduction of innovative ibuprofen products to the market[1].

Sources

  1. Market.us: Ibuprofen Market Size, Share, Growth | CAGR Of 7.8%
  2. GSK: Full year and fourth quarter 2021 - GSK
  3. Cognitive Market Research: Global Ibuprofen Market Report 2024
  4. StraitsResearch: Global Ibuprofen Market Size, Top Share, CAGR of 2.44%, Report
  5. GSK: Annual Report 2020 - GSK

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