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Last Updated: December 22, 2024

AZACTAM Drug Patent Profile


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Which patents cover Azactam, and what generic alternatives are available?

Azactam is a drug marketed by Bristol Myers Squibb and is included in two NDAs.

The generic ingredient in AZACTAM is aztreonam. There are eight drug master file entries for this compound. Four suppliers are listed for this compound. Additional details are available on the aztreonam profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Azactam

A generic version of AZACTAM was approved as aztreonam by FRESENIUS KABI USA on June 18th, 2010.

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Summary for AZACTAM
Drug patent expirations by year for AZACTAM
Drug Prices for AZACTAM

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Recent Clinical Trials for AZACTAM

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
National Institute of Allergy and Infectious Diseases (NIAID)Phase 1
Eastern Virginia Medical SchoolPhase 2
Virginia Commonwealth UniversityPhase 2

See all AZACTAM clinical trials

Pharmacology for AZACTAM

US Patents and Regulatory Information for AZACTAM

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bristol Myers Squibb AZACTAM aztreonam INJECTABLE;INJECTION 050580-002 Dec 31, 1986 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Bristol Myers Squibb AZACTAM IN PLASTIC CONTAINER aztreonam INJECTABLE;INJECTION 050632-003 May 24, 1989 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Bristol Myers Squibb AZACTAM aztreonam INJECTABLE;INJECTION 050580-003 Dec 31, 1986 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

EU/EMA Drug Approvals for AZACTAM

Company Drugname Inn Product Number / Indication Status Generic Biosimilar Orphan Marketing Authorisation Marketing Refusal
Gilead Sciences Ireland UC Cayston aztreonam EMEA/H/C/000996
Cayston is indicated for the suppressive therapy of chronic pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis (CF) aged 6 years and older.Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Authorised no no no 2009-09-21
>Company >Drugname >Inn >Product Number / Indication >Status >Generic >Biosimilar >Orphan >Marketing Authorisation >Marketing Refusal

AZACTAM Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Aztreonam (AZACTAM)

Introduction

Aztreonam, marketed under the brand name AZACTAM, is a synthetic beta-lactam antibiotic specifically designed to treat Gram-negative bacterial infections. The drug's unique monocyclic beta-lactam structure makes it resistant to certain bacterial enzymes, enhancing its effectiveness against resistant bacteria. Here, we delve into the market dynamics and financial trajectory of Aztreonam, highlighting its growth factors, investment prospects, and global significance.

Market Size and Growth

The Aztreonam market has been experiencing robust growth, driven by several key factors. As of 2023, the market size was valued at USD 1.5 billion and is projected to reach USD 2.42 billion by 2031, growing at a Compound Annual Growth Rate (CAGR) of 6%[1][4].

Drivers of Market Growth

Rising Antibiotic Resistance

One of the primary drivers of the Aztreonam market is the increasing incidence of antibiotic-resistant infections. As bacteria evolve and become resistant to existing antibiotics, the demand for effective treatments like Aztreonam grows significantly[1].

Increasing Prevalence of Infectious Diseases

The global rise in infectious diseases, particularly those caused by resistant strains of bacteria, has further fueled the demand for Aztreonam. This trend is especially notable in hospital settings where the risk of nosocomial infections is high[1].

Advancements in Drug Development

Ongoing research and development in the pharmaceutical industry have led to innovative formulations and improved delivery methods for Aztreonam. These advancements enhance the drug’s efficacy and extend its application to a broader range of infections. For instance, extended-release formulations are being developed to improve patient compliance and therapeutic outcomes[1].

Clinical Applications

Aztreonam is primarily used to treat infections caused by Gram-negative bacteria, including respiratory, urinary tract, and intra-abdominal infections. It is particularly effective against Pseudomonas aeruginosa and other resistant strains, making it a valuable tool in the fight against multi-drug-resistant infections and hospital-acquired infections[1].

Market Segmentation

The Aztreonam market is segmented based on type and application. The types include different purity levels (e.g., 97%, 98%, 99%) and dosage forms (e.g., 0.5g/Bottle, 1.0g/Bottle, 2.0g/Bottle). Applications include hospital pharmacies, retail pharmacies, and other healthcare settings[4][5].

Financial Performance

Historically, Aztreonam has shown strong financial performance. For example, in the first quarter of 1996, sales of Azactam (aztreonam) doubled to $19.9 million despite losing patent protection, as no generic rivals had been approved at that time[2].

Revenue Projections

The market is expected to continue its upward trajectory, with revenue projections indicating a sustained and significant expansion from 2023 to 2031. The global Aztreonam market is anticipated to reach USD 2.42 billion by 2031, driven by the increasing demand for effective treatments against resistant infections and ongoing advancements in drug development[1][5].

Investment Prospects

The Aztreonam market presents significant investment opportunities due to its pivotal role in the fight against resistant infections. Investors are attracted to companies developing new formulations and delivery methods for Aztreonam. Strategic partnerships and mergers and acquisitions among pharmaceutical companies are also driving innovation and growth in the sector[1].

Competitive Landscape

The competitive landscape of the Aztreonam market is characterized by several key players, including Shanxi PUDE Pharmaceutical, Hunan Kelun Pharmaceutical, and CSPC OUYI Pharmaceutical, among others. These companies are involved in various initiatives such as new product launches, collaborations, and mergers and acquisitions to strengthen their market presence and advance Aztreonam research and development[5].

Strategic Developments

Pharmaceutical companies are forming strategic partnerships to leverage combined expertise and resources, bringing innovative solutions to market faster. The market has witnessed several mergers and acquisitions as companies seek to strengthen their portfolios and expand their market presence. These strategic moves are expected to enhance the overall growth and innovation in the sector[1].

Challenges and Opportunities

While the Aztreonam market is growing, it also faces challenges such as the high development and approval costs of antimicrobial drugs. However, studies have shown that antimicrobial drugs, including Aztreonam, have lower expected capitalized development and approval costs compared to other drug cohorts, such as oncology drugs[3].

Opportunities

The increasing awareness of antibiotic resistance and the demand for effective treatments create favorable conditions for investment in the Aztreonam market. The development of new formulations and delivery methods, along with strategic partnerships, presents opportunities for growth and innovation[1].

Regional Analysis

The Aztreonam market is geographically segmented into regions such as North America, Europe, Asia-Pacific, and the Middle East and Africa. Each region has its own set of market dynamics, influenced by factors such as healthcare infrastructure, regulatory environments, and the prevalence of infectious diseases[5].

Conclusion

The Aztreonam market is poised for significant growth driven by the urgent need for effective treatments against resistant bacterial infections and ongoing innovations in drug development. With its unique properties and increasing clinical applications, Aztreonam is set to play a crucial role in the future of antibiotic therapy.

Key Takeaways

  • The Aztreonam market is valued at USD 1.5 billion in 2023 and is expected to reach USD 2.42 billion by 2031.
  • The market is driven by rising antibiotic resistance, increasing prevalence of infectious diseases, and advancements in drug development.
  • Aztreonam is effective against Gram-negative bacteria, including Pseudomonas aeruginosa and other resistant strains.
  • The market is segmented by type and application, with key players involved in strategic partnerships and innovations.
  • Investment prospects are significant due to the drug's pivotal role in treating resistant infections.

FAQs

What is Aztreonam used for?

Aztreonam is used to treat infections caused by Gram-negative bacteria, including respiratory, urinary tract, and intra-abdominal infections. It is particularly effective against Pseudomonas aeruginosa and other resistant strains[1].

What drives the growth of the Aztreonam market?

The growth of the Aztreonam market is driven by the rising incidence of antibiotic-resistant infections, the increasing prevalence of infectious diseases, and advancements in drug development such as new formulations and delivery methods[1].

What are the key segments of the Aztreonam market?

The Aztreonam market is segmented based on type (e.g., 0.5g/Bottle, 1.0g/Bottle, 2.0g/Bottle) and application (e.g., hospital pharmacies, retail pharmacies, others), as well as geographical regions[4][5].

Who are the key players in the Aztreonam market?

Key players include Shanxi PUDE Pharmaceutical, Hunan Kelun Pharmaceutical, CSPC OUYI Pharmaceutical, and others involved in various initiatives to advance Aztreonam research and development[5].

What are the investment prospects in the Aztreonam market?

The Aztreonam market presents significant investment opportunities due to its pivotal role in treating resistant infections. Investors are attracted to companies developing new formulations and delivery methods for Aztreonam[1].

Sources

  1. Market Research Intellect: "Unlocking the Potential of Aztreonam: Market Growth Amidst Rising Infections"
  2. PharmaTimes: "Elan says losses narrow in Q1"
  3. ASPE: "Antimicrobial Drugs Market Returns Analysis"
  4. Valuates Reports: "Aztreonam - Global Market Insights and Sales Trends 2024"
  5. Market Research Intellect: "Aztreonam for Injection Market Size, Scope And Forecast Report"

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