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Last Updated: December 22, 2024

BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE Drug Patent Profile


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When do Benazepril Hydrochloride And Hydrochlorothiazide patents expire, and when can generic versions of Benazepril Hydrochloride And Hydrochlorothiazide launch?

Benazepril Hydrochloride And Hydrochlorothiazide is a drug marketed by Ani Pharms, Apotex, Aurobindo Pharma Usa, Mylan Pharms Inc, Sandoz, and Sun Pharm Inds Ltd. and is included in seven NDAs.

The generic ingredient in BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE is benazepril hydrochloride; hydrochlorothiazide. There are fourteen drug master file entries for this compound. Seven suppliers are listed for this compound. Additional details are available on the benazepril hydrochloride; hydrochlorothiazide profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Benazepril Hydrochloride And Hydrochlorothiazide

A generic version of BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE was approved as benazepril hydrochloride; hydrochlorothiazide by ANI PHARMS on February 11th, 2004.

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Summary for BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE
Drug patent expirations by year for BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE
Recent Clinical Trials for BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Shanghai Jiao Tong University School of MedicinePhase 4
TSH Biopharm Corporation LimitedPhase 4
Ranbaxy Laboratories LimitedN/A

See all BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE clinical trials

Pharmacology for BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE

US Patents and Regulatory Information for BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Sun Pharm Inds Ltd BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE benazepril hydrochloride; hydrochlorothiazide TABLET;ORAL 077483-004 Sep 8, 2005 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Ani Pharms BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE benazepril hydrochloride; hydrochlorothiazide TABLET;ORAL 076342-001 Feb 11, 2004 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Mylan Pharms Inc BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE benazepril hydrochloride; hydrochlorothiazide TABLET;ORAL 076612-002 Feb 11, 2004 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Sandoz BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE benazepril hydrochloride; hydrochlorothiazide TABLET;ORAL 076631-004 Feb 11, 2004 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Ani Pharms BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE benazepril hydrochloride; hydrochlorothiazide TABLET;ORAL 076342-004 Feb 11, 2004 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Ani Pharms BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE benazepril hydrochloride; hydrochlorothiazide TABLET;ORAL 076348-002 Feb 11, 2004 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Apotex BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE benazepril hydrochloride; hydrochlorothiazide TABLET;ORAL 078794-004 Aug 21, 2014 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Benazepril Hydrochloride and Hydrochlorothiazide

Introduction

Benazepril hydrochloride and hydrochlorothiazide, a combination drug used to treat hypertension and chronic renal disease, is a significant player in the pharmaceutical market. This article delves into the market dynamics, key drivers, and the financial trajectory of this medication.

Market Overview

The market for benazepril hydrochloride and hydrochlorothiazide is part of the broader antihypertensive and cardiovascular drug market. This segment has seen substantial growth due to increasing prevalence of hypertension and related cardiovascular diseases globally.

Key Drivers of Market Growth

Increasing Prevalence of Hypertension

The global prevalence of hypertension is on the rise, with the World Health Organization (WHO) estimating that 1.13 billion people suffer from hypertension, a number expected to increase to 29% by 2025[1]. This increasing prevalence directly boosts the demand for antihypertensive medications like benazepril hydrochloride and hydrochlorothiazide.

Growing Geriatric Population

The aging population, particularly in developed regions, is more susceptible to various health issues, including hypertension and chronic renal disease. This demographic shift is a significant driver for the market growth of benazepril hydrochloride and hydrochlorothiazide[3].

Advances in Pharmaceutical R&D

Continuous research and development efforts to improve therapeutic efficacy and safety profiles of benazepril hydrochloride and hydrochlorothiazide have led to the development of novel formulations. These advancements are crucial in driving market expansion[3].

Government Support and Healthcare Spending

Government policies that encourage healthcare affordability and accessibility, along with rising healthcare spending, are major factors driving the market for benazepril hydrochloride and hydrochlorothiazide. These policies make the medication more accessible to a wider population[3].

Market Trends

New Product Launches

Recent years have seen the launch of generic versions of benazepril hydrochloride and hydrochlorothiazide tablets. For instance, Mylan received FDA approval for benazepril hydrochloride and hydrochlorothiazide tablets, which are the generic version of Novartis Pharmaceuticals' Lotensin HCT® Tablets[4].

Combination Therapies

The combination of benazepril hydrochloride (an ACE inhibitor) and hydrochlorothiazide (a diuretic) has proven effective in managing hypertension. This combination therapy is gaining traction due to its synergistic effects in reducing blood pressure and improving patient outcomes[4].

Financial Trajectory

Market Size and Projections

The benazepril hydrochloride market, which includes combination therapies with hydrochlorothiazide, was valued at USD 100 billion in 2023 and is expected to reach USD 147.75 billion by 2031, growing at a CAGR of 5% from 2024 to 2031[3].

Revenue Growth

The revenue growth of benazepril hydrochloride and hydrochlorothiazide is driven by the increasing demand for antihypertensive medications, government support for healthcare, and the launch of new generic and branded products. The market is expected to continue its upward trend due to these factors.

Competitive Landscape

Key Market Players

The market for benazepril hydrochloride and hydrochlorothiazide is competitive, with several key players including Mylan, Novartis, Teva, Aurobindo Pharma, and Lupin. These companies are involved in the development, manufacturing, and distribution of both branded and generic versions of the medication[1][4].

Generic Competition

The approval and launch of generic versions of benazepril hydrochloride and hydrochlorothiazide tablets have increased competition in the market. Generic drugs offer a cost-effective alternative, which can impact the market share of branded products but also expand the overall market size by making the medication more accessible[4].

Challenges and Restraints

Side Effects and Adverse Reactions

One of the significant challenges facing the market is the potential side effects and adverse reactions associated with benazepril hydrochloride and hydrochlorothiazide. These can include dizziness, cough, and electrolyte imbalances, which may hamper market growth if not managed effectively[1].

Regulatory Environment

The pharmaceutical industry is heavily regulated, and any changes in regulatory policies can impact the market. Ensuring compliance with FDA regulations and other international standards is crucial for maintaining market presence and growth.

Impact of COVID-19

The COVID-19 pandemic has had a mixed impact on the pharmaceutical industry. While it presented challenges in terms of supply chain disruptions, it also accelerated the development and approval of new medications, including those for COVID-19 management. This has indirectly benefited the market for benazepril hydrochloride and hydrochlorothiazide by highlighting the importance of healthcare infrastructure and the need for effective treatments for chronic conditions[1].

Medicare Coverage and Accessibility

In the United States, Medicare prescription drug plans cover benazepril hydrochloride and hydrochlorothiazide, with 99% of plans including this medication. This widespread coverage enhances accessibility and contributes to the market growth of the drug[5].

Key Takeaways

  • The market for benazepril hydrochloride and hydrochlorothiazide is driven by increasing prevalence of hypertension, growing geriatric population, and advances in pharmaceutical R&D.
  • The market is expected to grow at a CAGR of 5% from 2024 to 2031, reaching USD 147.75 billion by 2031.
  • Key players include Mylan, Novartis, and Teva, with generic competition playing a significant role.
  • Side effects and regulatory challenges are potential restraints on market growth.

FAQs

Q: What are the primary drivers of the benazepril hydrochloride and hydrochlorothiazide market?

A: The primary drivers include the increasing prevalence of hypertension, growing geriatric population, and advances in pharmaceutical R&D.

Q: What is the projected market size of benazepril hydrochloride by 2031?

A: The market is expected to reach USD 147.75 billion by 2031.

Q: Which companies are key players in the benazepril hydrochloride and hydrochlorothiazide market?

A: Key players include Mylan, Novartis, Teva, Aurobindo Pharma, and Lupin.

Q: Does Medicare cover benazepril hydrochloride and hydrochlorothiazide?

A: Yes, 99% of Medicare prescription drug plans cover this medication.

Q: What are the potential challenges facing the benazepril hydrochloride and hydrochlorothiazide market?

A: Potential challenges include side effects, adverse reactions, and regulatory environment changes.

Sources:

  1. Allied Market Research - Hydrochlorothiazide Market Size | Industry Growth, (2021-2030)
  2. Taylor & Francis Online - Reversed-Phase High Performance Liquid Chromatographic and ...
  3. Market Research Intellect - Benazepril Hydrochloride Market Size and Projections
  4. Mylan Investor Relations - Mylan Receives FDA Approval for Benazepril Hydrochloride Tablets ...
  5. GoodRx - Benazepril / HCTZ Medicare Coverage and Co-Pay Details - GoodRx

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