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Last Updated: December 22, 2024

BISOPROLOL FUMARATE Drug Patent Profile


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When do Bisoprolol Fumarate patents expire, and what generic alternatives are available?

Bisoprolol Fumarate is a drug marketed by Alembic, Aurobindo Pharma, Dash Pharms Natco, Harman Finochem, Novitium Pharma, Prinston Inc, Rubicon, Teva Pharms, Trupharma, Unichem, Zydus Lifesciences, Actavis Elizabeth, Apothecon, Cadila, Chartwell Rx, Edenbridge Pharms, Epic Pharma Llc, Glenmark Pharms Ltd, Ivax Sub Teva Pharms, Mylan, Teva, and Watson Labs Teva. and is included in twenty-four NDAs.

The generic ingredient in BISOPROLOL FUMARATE is bisoprolol fumarate; hydrochlorothiazide. There are twelve drug master file entries for this compound. Thirteen suppliers are listed for this compound. Additional details are available on the bisoprolol fumarate; hydrochlorothiazide profile page.

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Drug patent expirations by year for BISOPROLOL FUMARATE
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Recent Clinical Trials for BISOPROLOL FUMARATE

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SponsorPhase
Damanhour UniversityPhase 2
Alexandria UniversityPhase 2
Université de SherbrookeN/A

See all BISOPROLOL FUMARATE clinical trials

Pharmacology for BISOPROLOL FUMARATE
Medical Subject Heading (MeSH) Categories for BISOPROLOL FUMARATE
Anatomical Therapeutic Chemical (ATC) Classes for BISOPROLOL FUMARATE

US Patents and Regulatory Information for BISOPROLOL FUMARATE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Glenmark Pharms Ltd BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE bisoprolol fumarate; hydrochlorothiazide TABLET;ORAL 215995-001 Jan 26, 2022 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Chartwell Rx BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE bisoprolol fumarate; hydrochlorothiazide TABLET;ORAL 075527-001 Sep 25, 2000 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Mylan BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE bisoprolol fumarate; hydrochlorothiazide TABLET;ORAL 075768-003 Sep 25, 2000 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Watson Labs Teva BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE bisoprolol fumarate; hydrochlorothiazide TABLET;ORAL 075469-002 Sep 25, 2000 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Ivax Sub Teva Pharms BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE bisoprolol fumarate; hydrochlorothiazide TABLET;ORAL 075632-002 Sep 27, 2000 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Novitium Pharma BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE bisoprolol fumarate; hydrochlorothiazide TABLET;ORAL 215562-001 Nov 4, 2021 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Teva BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE bisoprolol fumarate; hydrochlorothiazide TABLET;ORAL 075686-003 Jan 19, 2001 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

BISOPROLOL FUMARATE Market Analysis and Financial Projection Experimental

Bisoprolol Fumarate Market Dynamics and Financial Trajectory

Introduction to Bisoprolol Fumarate

Bisoprolol fumarate is a beta-blocker primarily used to treat hypertension (high blood pressure) and heart failure. As a selective beta-1 adrenergic antagonist, it reduces heart rate and the workload on the heart, leading to lower blood pressure and improved heart function[1][5].

Market Growth Drivers

The bisoprolol fumarate market is experiencing significant growth driven by several key factors:

Rising Prevalence of Cardiovascular Diseases

The global increase in cardiovascular diseases such as hypertension, heart failure, and coronary heart disease is a major driver. As populations age and lifestyle-related diseases become more prevalent, the demand for effective cardiovascular treatments like bisoprolol fumarate is on the rise[1][4].

Expanding Generic Market

The expiration of patents for bisoprolol fumarate has led to the entry of generic versions, making the drug more affordable and accessible to patients in developing and low-income countries. This has significantly boosted market growth[1].

Advancements in Drug Formulations

Innovations in drug delivery systems, such as long-acting formulations and once-daily dosing, have improved patient compliance and therapeutic efficacy. Additionally, the development of liquid formulations for patients with swallowing difficulties further expands the market[1].

Combination Therapies

The trend towards combination therapies, where bisoprolol is prescribed alongside other cardiovascular drugs like ACE inhibitors and diuretics, has enhanced therapeutic benefits and contributed to market growth[1].

Market Size and Projections

The bisoprolol fumarate market is projected to see substantial growth in the coming years:

Current Market Size

The market size was approximately $1.84 billion in 2023 and is expected to grow to $2 billion in 2024, with a compound annual growth rate (CAGR) of 8.6%[4].

Future Projections

By 2028, the market is forecasted to reach $2.8 billion, maintaining a CAGR of 8.7%. This growth is attributed to factors such as the expansion of cardiovascular specialty clinics, enhanced patient support programs, and increased funding for cardiovascular health initiatives[4].

Segmentation of the Market

The bisoprolol fumarate market can be segmented in several ways:

By Type

The market is segmented into tablets and capsules, with tablets being the more common form due to their ease of administration and higher bioavailability[4].

By Distribution Channels

The drug is distributed through hospital pharmacies, retail pharmacies, and other distribution channels. Hospital pharmacies play a significant role due to the frequent need for cardiovascular medications in hospital settings[4].

By Application

Bisoprolol fumarate is used primarily for high blood pressure, coronary heart disease, angina pectoris, and other cardiovascular applications. High blood pressure remains the most significant application area[4].

Regional Analysis

The market is split across various regions, with significant growth observed in:

Emerging Markets

Asia-Pacific, Latin America, and parts of Africa are seeing increased adoption due to the drug's effectiveness, cost-efficiency, and accessibility. Government healthcare reforms in these regions are also driving the market by ensuring the widespread availability of heart disease treatments[1].

Developed Markets

In regions like Europe and North America, the market is driven by advanced healthcare systems, higher awareness of hypertension management, and increased healthcare expenditure[4].

Economic Impact and Cost Savings

Bisoprolol fumarate not only provides health benefits but also offers significant cost savings:

Reduced Hospital Admissions

Studies such as the Cardiac Insufficiency Bisoprolol Study (CIBIS II) have shown that bisoprolol therapy reduces hospital admissions, days spent in hospital, and costs associated with hospital care. This results in a 5-10% reduction in healthcare costs even after accounting for the cost of the drug and additional medical visits[2].

Long-Term Cost Benefits

The long-term use of bisoprolol fumarate in managing chronic heart failure leads to sustained cost savings for healthcare systems and patients. This is due to reduced need for hospitalizations and other costly medical interventions[2].

Investment Opportunities and Business Potential

The bisoprolol fumarate market presents several investment opportunities:

Research and Development

Investments in R&D focused on improving drug formulations and expanding distribution networks in emerging markets are expected to drive growth. Innovations in drug delivery systems and patient-centric therapies are particularly promising areas[1].

Strategic Partnerships

Pharmaceutical companies are entering into strategic partnerships with healthcare providers, NGOs, and governments to enhance the availability and affordability of bisoprolol fumarate. These partnerships facilitate the development of new formulations and ensure economies of scale[1].

Challenges and Future Directions

While the market is poised for growth, there are some challenges to consider:

Regulatory Environment

Changes in regulatory policies and healthcare reforms can impact the market. However, current trends suggest that governments are supportive of making cardiovascular treatments more accessible[1].

Competition from New Therapies

The emergence of new cardiovascular therapies could potentially challenge the dominance of bisoprolol fumarate. However, its established efficacy and cost-effectiveness make it a strong contender in the market[4].

Key Takeaways

  • The bisoprolol fumarate market is driven by the global demand for effective cardiovascular treatments.
  • Generic versions and advancements in drug formulations are key growth drivers.
  • The market is expected to grow significantly, reaching $2.8 billion by 2028.
  • Emerging markets and strategic partnerships are crucial for future growth.
  • Bisoprolol fumarate offers significant cost savings in healthcare by reducing hospital admissions and long-term care costs.

Frequently Asked Questions

Q: What is the primary use of bisoprolol fumarate? A: Bisoprolol fumarate is primarily used to treat high blood pressure (hypertension) and heart failure.

Q: How does bisoprolol fumarate work? A: Bisoprolol fumarate works by blocking certain receptors in the heart, leading to a reduction in heart rate and the workload on the heart, resulting in lower blood pressure and improved heart function.

Q: What are the key drivers of the bisoprolol fumarate market? A: The key drivers include the rising prevalence of cardiovascular diseases, the expansion of generic markets, advancements in drug formulations, and the trend towards combination therapies.

Q: What are the projected market sizes for bisoprolol fumarate? A: The market size is expected to grow from $1.84 billion in 2023 to $2 billion in 2024 and reach $2.8 billion by 2028.

Q: How does bisoprolol fumarate impact healthcare costs? A: Bisoprolol fumarate reduces healthcare costs by decreasing hospital admissions, days spent in hospital, and associated care costs, leading to a 5-10% reduction in overall healthcare expenditure.

Sources

  1. Market Research Intellect: "The Future of Cardiovascular Treatment: Bisoprolol Fumarate Market Shows Strong Growth"
  2. PubMed: "Reduced costs with bisoprolol treatment for heart failure"
  3. Market Research Intellect: "Global Bisoprolol Fumarate Market Size, Trends and Projections"
  4. The Business Research Company: "Bisoprolol Market Report 2024 - Growth And Trends Analysis"
  5. FDA: "Zebeta (Bisoprolol Fumarate) Tablets"

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