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Last Updated: December 22, 2024

CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE Drug Patent Profile


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When do Chlordiazepoxide Hydrochloride And Clidinium Bromide patents expire, and when can generic versions of Chlordiazepoxide Hydrochloride And Clidinium Bromide launch?

Chlordiazepoxide Hydrochloride And Clidinium Bromide is a drug marketed by Alembic, Alkem Labs Ltd, Amneal, Aurobindo Pharma Ltd, Chartwell Rx, Corepharma, Dr Reddys, Micro Labs, Misemer, Nuvo Pharms Inc, Teva Pharms Usa, Torrent, and Winder Labs Llc. and is included in thirteen NDAs.

The generic ingredient in CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE is chlordiazepoxide hydrochloride; clidinium bromide. There are nine drug master file entries for this compound. Fifteen suppliers are listed for this compound. Additional details are available on the chlordiazepoxide hydrochloride; clidinium bromide profile page.

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Summary for CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE
US Patents:0
Applicants:13
NDAs:13
Finished Product Suppliers / Packagers: 14
What excipients (inactive ingredients) are in CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE?CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE excipients list
DailyMed Link:CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE at DailyMed
Drug patent expirations by year for CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE
Pharmacology for CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE

US Patents and Regulatory Information for CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Alembic CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE chlordiazepoxide hydrochloride; clidinium bromide CAPSULE;ORAL 216969-001 Sep 15, 2023 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Dr Reddys CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE chlordiazepoxide hydrochloride; clidinium bromide CAPSULE;ORAL 214698-001 May 10, 2021 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Aurobindo Pharma Ltd CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE chlordiazepoxide hydrochloride; clidinium bromide CAPSULE;ORAL 216419-001 Sep 14, 2023 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Torrent CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE chlordiazepoxide hydrochloride; clidinium bromide CAPSULE;ORAL 217385-001 Dec 14, 2023 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Micro Labs CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE chlordiazepoxide hydrochloride; clidinium bromide CAPSULE;ORAL 215835-001 Jul 19, 2022 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Alkem Labs Ltd CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE chlordiazepoxide hydrochloride; clidinium bromide CAPSULE;ORAL 214065-001 Apr 26, 2021 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Chlordiazepoxide Hydrochloride and Clidinium Bromide

Introduction

Chlordiazepoxide hydrochloride and clidinium bromide, often combined in medications like Librax, are crucial in treating various gastrointestinal and anxiety-related disorders. This article delves into the market dynamics, financial trajectory, and key factors influencing the demand for these drugs.

Market Overview

The market for chlordiazepoxide hydrochloride and clidinium bromide is part of the broader antacids and gastrointestinal drugs market. This segment is experiencing significant growth due to increasing gastrointestinal issues such as gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), and peptic ulcers[1][3].

Key Applications

Treatment of Gastrointestinal Disorders

Chlordiazepoxide and clidinium bromide are used in combination to treat peptic ulcers, IBS, and enterocolitis. Clidinium bromide, an anticholinergic, helps reduce stomach spasms and cramps, while chlordiazepoxide, a benzodiazepine, decreases abnormal electrical activity in the brain, providing relief from anxiety and related symptoms[4].

Increasing Prevalence of Gastrointestinal Illnesses

The growing prevalence of gastrointestinal illnesses is a major driver for the market. As the global population ages and lifestyle changes lead to more digestive problems, the demand for effective treatments like clidinium bromide and chlordiazepoxide hydrochloride increases[3].

Market Size and Projections

Clidinium Bromide Market

The clidinium bromide market was valued at USD 1 billion in 2023 and is expected to reach USD 1.77 billion by 2031, growing at a compound annual growth rate (CAGR) of 6% from 2024 to 2031. This growth is driven by the rise in gastrointestinal illnesses and the increasing awareness of gastrointestinal health[3].

Antacids Market

The broader antacids market, which includes products like chlordiazepoxide hydrochloride and clidinium bromide, is also expected to grow significantly. The North American antacids market, in particular, is anticipated to hold a significant share due to increasing GERD and lifestyle changes leading to gastrointestinal problems[1].

Regulatory Approvals and Product Innovations

FDA Approvals

Recent FDA approvals have contributed significantly to market growth. For example, the approval of glycopyrrolate orally disintegrating tablets (Dartisla ODT) by the FDA in December 2021 and the final approval for Zydus Lifesciences to market Famotidine tablets in June 2022 have boosted the market for antacids and related gastrointestinal treatments[1].

New Product Introductions

Companies like Dr. Reddy's Laboratories have introduced new products, such as generic chlordiazepoxide hydrochloride and clidinium bromide capsules, which are gaining traction in the market. These new introductions are expected to further accelerate market growth[1].

Geographical Trends

North America

North America is expected to hold a significant share of the market due to the increasing trend of self-medication and the rising incidence of gastrointestinal problems among the population. The demand for over-the-counter digestive products, including antacids, is on the rise in this region[1].

Global Expansion

The market is also expanding in other regions, including Europe, Asia-Pacific, and emerging markets, driven by increasing healthcare access and a growing awareness of gastrointestinal health issues[3].

Competitive Landscape

Key Players

The market for chlordiazepoxide hydrochloride and clidinium bromide is competitive, with key players including Pfizer, Sanofi, Novartis, Teva Pharmaceutical, Mylan, Sun Pharmaceutical, Dr. Reddy's Laboratories, and others. These companies are investing in research and development to bring new and reliable products to the market[3].

Challenges and Opportunities

Dependence and Withdrawal

One of the significant challenges associated with chlordiazepoxide hydrochloride is the risk of physical dependence and withdrawal reactions. This necessitates careful dosage management and gradual tapering to avoid adverse effects[2].

Combination Therapies

The market is seeing a trend towards combination therapies that include clidinium bromide and other drugs. This approach is gaining popularity due to its effectiveness in managing symptoms of gastrointestinal illnesses and reducing the need for multiple medications[3].

Financial Performance

The financial performance of the market is robust, driven by increasing demand and new product approvals. The clidinium bromide market, for instance, is expected to grow from USD 1 billion in 2023 to USD 1.77 billion by 2031, indicating a strong financial trajectory[3].

Key Takeaways

  • The market for chlordiazepoxide hydrochloride and clidinium bromide is driven by the increasing prevalence of gastrointestinal illnesses.
  • Recent FDA approvals and new product introductions are significant growth drivers.
  • North America is expected to hold a significant share of the market due to self-medication trends and rising gastrointestinal problems.
  • The competitive landscape includes major pharmaceutical companies investing in R&D.
  • Challenges such as dependence and withdrawal reactions need careful management.

FAQs

What are the primary uses of chlordiazepoxide hydrochloride and clidinium bromide?

Chlordiazepoxide hydrochloride and clidinium bromide are used in combination to treat peptic ulcers, irritable bowel syndrome (IBS), and enterocolitis, as well as to manage anxiety-related symptoms[4].

What is the expected growth rate of the clidinium bromide market?

The clidinium bromide market is expected to grow at a CAGR of 6% from 2024 to 2031, reaching USD 1.77 billion by 2031[3].

Which region is expected to hold a significant share of the antacids market?

North America is expected to hold a significant share of the antacids market due to increasing GERD and lifestyle changes leading to gastrointestinal problems[1].

What are the risks associated with long-term use of chlordiazepoxide hydrochloride?

Long-term use of chlordiazepoxide hydrochloride can lead to clinically significant physical dependence and withdrawal reactions, which can be life-threatening if not managed properly[2].

Who are the key players in the market for chlordiazepoxide hydrochloride and clidinium bromide?

Key players include Pfizer, Sanofi, Novartis, Teva Pharmaceutical, Mylan, Sun Pharmaceutical, Dr. Reddy's Laboratories, and others[3].

Sources

  1. Mordor Intelligence: Antacids Market Trends.
  2. DailyMed: CHLORDIAZEPOXIDE HYDROCHLORIDE capsule.
  3. Market Research Intellect: Global Clidinium Bromide Market.
  4. MedlinePlus: Chlordiazepoxide and Clidinium: MedlinePlus Drug Information.

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