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Last Updated: December 23, 2024

CONRAY Drug Patent Profile


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Which patents cover Conray, and what generic alternatives are available?

Conray is a drug marketed by Liebel-flarsheim and Mallinckrodt and is included in four NDAs.

The generic ingredient in CONRAY is iothalamate sodium. There is one drug master file entry for this compound. Additional details are available on the iothalamate sodium profile page.

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Summary for CONRAY
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Pharmacology for CONRAY

US Patents and Regulatory Information for CONRAY

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Liebel-flarsheim CONRAY iothalamate meglumine INJECTABLE;INJECTION 013295-001 Approved Prior to Jan 1, 1982 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Mallinckrodt CONRAY 400 iothalamate sodium INJECTABLE;INJECTION 014295-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Liebel-flarsheim CONRAY 30 iothalamate meglumine INJECTABLE;INJECTION 016983-001 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Mallinckrodt CONRAY 325 iothalamate sodium INJECTABLE;INJECTION 017685-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

CONRAY Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Conray

Introduction

Conray, a diagnostic radiopaque medium containing iothalamate meglumine, is widely used in various medical imaging procedures. To understand its market dynamics and financial trajectory, it is essential to delve into its indications, usage, market trends, and the broader healthcare landscape.

Indications and Usage

Conray is indicated for a range of diagnostic procedures, including excretory urography, cerebral angiography, peripheral arteriography, venography, arthrography, and direct cholangiography, among others[1][4].

Market Demand

The demand for diagnostic imaging agents like Conray is driven by the increasing need for accurate and detailed medical imaging. This need is fueled by the rising incidence of chronic diseases, the aging population, and advancements in medical technology. For instance, the use of Conray in procedures such as contrast enhancement of computed tomographic scans for detecting and evaluating lesions in various organs is a significant driver of demand[4].

Competitive Landscape

The market for diagnostic imaging agents is competitive, with several other contrast media available. However, Conray's versatility and the range of procedures it can be used for position it as a valuable option for healthcare providers. The competition is influenced by factors such as the efficacy, safety profile, and cost-effectiveness of the contrast agents[4].

Pricing and Cost-Effectiveness

The pricing of Conray and other diagnostic agents is a critical factor in their market dynamics. Healthcare systems and insurance providers often evaluate the cost-effectiveness of these agents. Agencies like the National Institute for Health and Clinical Excellence (NICE) and the Pharmaceutical Benefits Advisory Committee (PBAC) consider both the clinical effectiveness and cost-effectiveness when making coverage decisions[5].

Financial Trajectory

Revenue Streams

The revenue generated by Conray comes from its widespread use in various medical procedures. The product is marketed by several companies, including Liebel Flarsheim Company LLC and Mallinckrodt, which indicates a diversified revenue stream[1][4].

Market Growth

The market for diagnostic imaging agents is expected to grow due to the increasing demand for advanced medical imaging. This growth is driven by technological advancements, an aging population, and the rising prevalence of chronic diseases. As a result, the financial trajectory for Conray is likely to be positive, with steady revenue growth anticipated in the coming years.

Expenditure Trends

Expenditures on pharmaceuticals, including diagnostic agents, are among the fastest-growing sectors within healthcare in developed countries. For example, federal expenditures for Part D of Medicare and Medicaid in the United States are significant, and these expenditures are projected to continue growing[5].

Regulatory Environment

The regulatory environment plays a crucial role in the market dynamics and financial trajectory of Conray. Regulatory approvals and guidelines set by agencies such as the FDA influence the availability and usage of the drug. Additionally, guidelines on cost-effectiveness and coverage decisions by health insurance providers can impact the financial performance of Conray[5].

Safety and Adverse Effects

The safety profile of Conray is another critical factor. While generally safe, Conray can cause severe cutaneous adverse reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis. These risks can affect its market acceptance and financial performance if not managed properly[4].

Patient and Healthcare Provider Preferences

Patient and healthcare provider preferences also influence the market dynamics. The preference for a diagnostic agent that is effective, safe, and easy to administer can drive the demand for Conray. For instance, the rapid excretion of Conray through the kidneys and its ability to provide clear radiographic images make it a preferred choice for many procedures[1][4].

Global Health Trends

Global health trends, such as the increasing burden of chronic diseases and the need for advanced diagnostic tools, also impact the market for Conray. The COVID-19 pandemic, for example, has highlighted the importance of robust diagnostic capabilities, which could further boost the demand for diagnostic imaging agents[3].

Key Takeaways

  • Versatile Indications: Conray is used in a wide range of diagnostic procedures, making it a valuable asset in medical imaging.
  • Growing Demand: The demand for diagnostic imaging agents is increasing due to the rising incidence of chronic diseases and advancements in medical technology.
  • Competitive Landscape: The market is competitive, but Conray's efficacy and safety profile position it favorably.
  • Cost-Effectiveness: The cost-effectiveness of Conray is a critical factor in its market dynamics and financial trajectory.
  • Regulatory Environment: Regulatory approvals and guidelines significantly influence the market dynamics and financial performance of Conray.
  • Safety Profile: Managing the safety risks associated with Conray is crucial for maintaining market acceptance.

FAQs

What are the primary indications for Conray?

Conray is indicated for use in excretory urography, cerebral angiography, peripheral arteriography, venography, arthrography, and various other diagnostic procedures[1][4].

How is Conray excreted from the body?

Conray is rapidly transported through the circulatory system to the kidneys and is excreted unchanged in the urine by glomerular filtration. In patients with severe renal impairment, excretion through the gallbladder and into the small intestine increases[1][4].

What are the potential adverse effects of Conray?

Conray can cause severe cutaneous adverse reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis. Other adverse effects include reactions related to its high osmolality and potential allergic reactions[4].

How does the regulatory environment impact Conray's market dynamics?

Regulatory approvals and guidelines set by agencies such as the FDA influence the availability and usage of Conray. Coverage decisions by health insurance providers also impact its financial performance[5].

What are the key factors driving the demand for Conray?

The demand for Conray is driven by the increasing need for accurate and detailed medical imaging, the rising incidence of chronic diseases, and advancements in medical technology[4].

Sources

  1. DrugBank: Iothalamic acid: Uses, Interactions, Mechanism of Action.
  2. White House: FACT SHEET: White House Releases 2022 National Drug Control Strategy.
  3. UNODC: DRUG MARKET TRENDS.
  4. Drugs.com: Conray: Package Insert / Prescribing Information.
  5. JAMA Network: Using Effectiveness and Cost-effectiveness to Make Drug Coverage Decisions.

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