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Last Updated: December 22, 2024

LEUCOVORIN CALCIUM PRESERVATIVE FREE Drug Patent Profile


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When do Leucovorin Calcium Preservative Free patents expire, and what generic alternatives are available?

Leucovorin Calcium Preservative Free is a drug marketed by Am Regent, Fresenius Kabi Usa, Hikma, Mylan Labs Ltd, Sagent Pharms, Sagent Pharms Inc, Hospira, and Teva Parenteral. and is included in twelve NDAs.

The generic ingredient in LEUCOVORIN CALCIUM PRESERVATIVE FREE is leucovorin calcium. There are nine drug master file entries for this compound. Fourteen suppliers are listed for this compound. Additional details are available on the leucovorin calcium profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Leucovorin Calcium Preservative Free

A generic version of LEUCOVORIN CALCIUM PRESERVATIVE FREE was approved as leucovorin calcium by HIKMA on September 14th, 1987.

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Summary for LEUCOVORIN CALCIUM PRESERVATIVE FREE
Drug patent expirations by year for LEUCOVORIN CALCIUM PRESERVATIVE FREE
Pharmacology for LEUCOVORIN CALCIUM PRESERVATIVE FREE
Drug ClassFolate Analog

US Patents and Regulatory Information for LEUCOVORIN CALCIUM PRESERVATIVE FREE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Am Regent LEUCOVORIN CALCIUM PRESERVATIVE FREE leucovorin calcium INJECTABLE;INJECTION 040338-001 Jan 31, 2001 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Teva Parenteral LEUCOVORIN CALCIUM PRESERVATIVE FREE leucovorin calcium SOLUTION;INTRAMUSCULAR, INTRAVENOUS 040332-001 Jun 28, 1999 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Mylan Labs Ltd LEUCOVORIN CALCIUM PRESERVATIVE FREE leucovorin calcium INJECTABLE;INJECTION 203800-002 May 19, 2017 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Hikma LEUCOVORIN CALCIUM PRESERVATIVE FREE leucovorin calcium INJECTABLE;INJECTION 040056-001 May 23, 1995 AP RX No Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

LEUCOVORIN CALCIUM PRESERVATIVE FREE Market Analysis and Financial Projection Experimental

Leucovorin Calcium Market Dynamics and Financial Trajectory

Market Overview

The global market for Leucovorin Calcium is experiencing significant growth, driven by several key factors. Here’s a detailed look at the market dynamics and financial trajectory of this essential drug.

Growing Demand for Cancer Treatment

One of the primary drivers of the Leucovorin Calcium market is the increasing prevalence of cancer worldwide. In 2020, approximately 19.3 million new cancer cases were recorded globally, which is projected to drive the demand for cancer treatment, including the use of Leucovorin Calcium[1].

Role in Chemotherapy

Leucovorin Calcium is crucial in chemotherapy regimens, particularly when used in combination with 5-fluorouracil (5-FU) for the treatment of advanced colorectal cancer. Clinical studies have shown that Leucovorin Calcium significantly improves response rates and median survival times when used with 5-FU[2].

Increasing Prevalence of Folate Deficiency

Apart from its role in cancer treatment, Leucovorin Calcium is also indicated for the treatment of megaloblastic anemias due to folic acid deficiency. The rising awareness and diagnosis of folate deficiency are further boosting the demand for this drug[5].

Innovations in Drug Formulation

Pharmaceutical companies are innovating in drug formulation, developing more stable and effective forms of Leucovorin Calcium, such as extended-release injections and pre-filled syringes. These innovations enhance ease of use, patient compliance, and reduce the overall cost of the drug, making it more accessible[3].

Regional Market Dynamics

North America

The North American market is expected to exhibit significant revenue growth due to advanced healthcare systems, high healthcare expenditure, and a large base of aged people. The high prevalence of cancer in this region also contributes to the market growth[4].

Europe

Europe is seeing a rise in disposable income levels, increasing incidence rates of chronic diseases like cancer and type II diabetes, and an aging population. These factors are driving the market revenue growth in this region[4].

Asia Pacific

The Asia Pacific region is expected to develop at the fastest revenue CAGR during the projected period. This growth is attributed to advancing healthcare systems, improving medical facilities, and rising cases of cancer and blood cell disorders[4].

Competitive Landscape

The global Leucovorin Calcium market is competitive, with prominent players involved in manufacturing, marketing, and distributing the drug. Companies are also engaged in research and development to create innovative and more effective therapies. Mergers and acquisitions, partnerships, and collaborations are common strategies to strengthen market positions[4].

Financial Trajectory

Revenue Growth

The global Leucovorin Calcium market is estimated to register a revenue CAGR of 13.8% from 2023 to 2031. This significant growth is driven by increasing cases of blood-related disorders, the rising prevalence of cancer, and an increase in awareness of the effectiveness of combination therapy[4].

Investment Opportunities

Investing in R&D for new drug formulations or novel drug delivery systems offers a competitive edge in the market. The expiration of patents for many Leucovorin products is expected to lead to a rise in generic versions, which will be particularly significant in emerging regions. Expanding distribution and partnerships in these regions also presents lucrative opportunities[3].

Market Segments

The injections segment dominates the global Leucovorin Calcium industry. The blood cell disorders segment accounts for a significant revenue share, driven by the rising prevalence of these conditions[4].

Challenges and Restraints

Despite the growth, the market faces some challenges, including the high cost of the drug and the availability of alternatives. These factors can restrain revenue growth, especially in regions with limited healthcare budgets[4].

Key Trends

Cost-Effectiveness

The cost-effectiveness of Leucovorin Calcium, especially in its generic form, makes it an accessible option in developing countries. This is a significant trend driving the market growth in emerging regions[3].

Healthcare Infrastructure Expansion

As healthcare infrastructure expands globally, particularly in emerging markets, the demand for Leucovorin Calcium is set to grow. This expansion is crucial for the future of oncology and healthcare worldwide[3].

"The Leucovorin Calcium Injection market is on an upward trajectory, driven by its essential role in cancer treatment and folate deficiency management. With rising cancer cases, growing awareness of folate deficiency, and innovations in drug delivery, this market presents a wealth of opportunities for pharmaceutical businesses and investors."[3]

Conclusion

The Leucovorin Calcium market is poised for significant growth, driven by the increasing prevalence of cancer, innovations in drug formulation, and expanding healthcare infrastructure. While challenges such as high costs and availability of alternatives exist, the overall trajectory indicates a promising future for this segment of the pharmaceutical industry.

Key Takeaways

  • The global Leucovorin Calcium market is expected to grow at a significant CAGR due to the rising prevalence of cancer and folate deficiency.
  • Innovations in drug formulation, such as extended-release injections and pre-filled syringes, are enhancing patient compliance and reducing costs.
  • The market is driven by regional dynamics, with North America, Europe, and the Asia Pacific showing significant growth.
  • The competitive landscape is intense, with companies focusing on R&D and strategic partnerships.
  • Despite challenges, the market presents lucrative investment opportunities, especially in emerging regions.

FAQs

Q: What is the primary use of Leucovorin Calcium in medical treatment?

A: Leucovorin Calcium is primarily used in combination with 5-fluorouracil (5-FU) for the treatment of advanced colorectal cancer and as an antidote to drugs that act as folic acid antagonists[2][5].

Q: What are the key drivers of the Leucovorin Calcium market?

A: The key drivers include the increasing prevalence of cancer, rising awareness of folate deficiency, and innovations in drug formulation and delivery mechanisms[1][3][4].

Q: Which regions are expected to show significant growth in the Leucovorin Calcium market?

A: North America, Europe, and the Asia Pacific are expected to exhibit significant revenue growth due to various regional factors such as advanced healthcare systems, rising incidence of chronic diseases, and improving medical facilities[4].

Q: What are the challenges facing the Leucovorin Calcium market?

A: The high cost of the drug and the availability of alternatives are some of the major restraints for revenue growth in the global Leucovorin Calcium market[4].

Q: What investment opportunities exist in the Leucovorin Calcium market?

A: Investing in R&D for new drug formulations, generic manufacturing, and expanding distribution in emerging regions present lucrative opportunities for pharmaceutical businesses and investors[3].

More… ↓

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