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Last Updated: December 22, 2024

MARCAINE HYDROCHLORIDE PRESERVATIVE FREE Drug Patent Profile


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Which patents cover Marcaine Hydrochloride Preservative Free, and when can generic versions of Marcaine Hydrochloride Preservative Free launch?

Marcaine Hydrochloride Preservative Free is a drug marketed by Hospira and is included in one NDA.

The generic ingredient in MARCAINE HYDROCHLORIDE PRESERVATIVE FREE is bupivacaine hydrochloride. There are twelve drug master file entries for this compound. Twenty-two suppliers are listed for this compound. Additional details are available on the bupivacaine hydrochloride profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Marcaine Hydrochloride Preservative Free

A generic version of MARCAINE HYDROCHLORIDE PRESERVATIVE FREE was approved as bupivacaine hydrochloride by HOSPIRA on February 17th, 1986.

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Summary for MARCAINE HYDROCHLORIDE PRESERVATIVE FREE
Drug patent expirations by year for MARCAINE HYDROCHLORIDE PRESERVATIVE FREE
Recent Clinical Trials for MARCAINE HYDROCHLORIDE PRESERVATIVE FREE

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SponsorPhase
Suez Canal UniversityN/A
University of PennsylvaniaPhase 3

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Pharmacology for MARCAINE HYDROCHLORIDE PRESERVATIVE FREE

US Patents and Regulatory Information for MARCAINE HYDROCHLORIDE PRESERVATIVE FREE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Hospira MARCAINE HYDROCHLORIDE PRESERVATIVE FREE bupivacaine hydrochloride INJECTABLE;INJECTION 016964-012 Approved Prior to Jan 1, 1982 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Hospira MARCAINE HYDROCHLORIDE PRESERVATIVE FREE bupivacaine hydrochloride INJECTABLE;INJECTION 016964-005 Approved Prior to Jan 1, 1982 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Hospira MARCAINE HYDROCHLORIDE PRESERVATIVE FREE bupivacaine hydrochloride INJECTABLE;INJECTION 016964-009 Approved Prior to Jan 1, 1982 AP RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

MARCAINE HYDROCHLORIDE PRESERVATIVE FREE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Marcaine Hydrochloride Preservative Free

Introduction to Marcaine Hydrochloride Preservative Free

Marcaine Hydrochloride, commonly known by its brand name Marcaine, is a local anesthetic belonging to the amide class. It is widely used for various surgical, diagnostic, therapeutic, and obstetrical treatments to provide local or regional anesthesia and analgesia.

Market Size and Growth Prospects

The global market for bupivacaine hydrochloride, the active ingredient in Marcaine, is projected to experience significant growth. By 2030, the bupivacaine injection market is expected to reach USD 1,447 million, growing at a Compound Annual Growth Rate (CAGR) of 5.6% from 2020 to 2030[4].

Key Drivers of Market Growth

Rise in Surgical Procedures

The increasing number of surgical procedures, including cosmetic surgeries, dental procedures, and plastic surgeries, is a major driver of the local anesthesia drugs market. Approximately 65% of total surgical procedures require post-operative pain management, which is expected to boost the demand for local anesthetics like Marcaine Hydrochloride[3].

Aging Population and Chronic Diseases

The rise in the older population suffering from chronic diseases also contributes to the growth of the bupivacaine injection market. As the global population ages, the demand for surgical and diagnostic procedures increases, thereby driving the need for local anesthetics[4].

Advancements in Drug Delivery Systems

Advancements in drug delivery systems are expected to further drive the market. New and effective drugs such as levobupivacaine and ropivacaine, along with improvements in existing formulations like Marcaine Hydrochloride, are enhancing the market's growth prospects[3].

Market Segmentation

By Type

The bupivacaine injection market is segmented by type, with concentrations such as 0.25%, 0.5%, and 0.75%. The 0.25% bupivacaine injection sub-segment is expected to be the most profitable during the forecast period due to its widespread use in various surgical and dental procedures[4].

By End-User

The market is also segmented by end-user, with hospitals, clinics, and other healthcare facilities being the primary consumers. Hospitals are expected to dominate this segment due to the high volume of surgical procedures performed in these settings[4].

By Region

North America is anticipated to dominate the global bupivacaine injection market, driven by the expanding patient population and the rise in medical and dental surgical procedures. The Asia-Pacific region is also expected to register significant growth during the forecast period[4].

Financial Trajectory

Current Market Value

As of 2023, the global bupivacaine injection market had a significant market share, with the global local anesthesia drugs market valued at approximately USD 4.01 billion. This value is projected to increase to USD 5.14 billion by 2030, growing at a CAGR of 3.6% from 2024 to 2030[3].

Pricing and Cost Considerations

The cost of Marcaine Hydrochloride can vary based on the concentration and quantity. For example, a 0.25% preservative-free injectable solution can cost around $51.95 for 100 milliliters. Generic versions and discount programs can further reduce the cost, making it more accessible to patients[2].

Impact of COVID-19

The COVID-19 pandemic had a mixed impact on the market. While there were disruptions in supply chains and a temporary halt in non-emergent surgical procedures, the use of local anesthesia like Marcaine Hydrochloride became more popular due to its benefits and low risk of viral transmission. This trend is expected to positively impact the market during the forecast period[4].

Competitive Landscape

The bupivacaine injection market is saturated with several key players, including Pfizer, Baxter, Fresenius Kabi, and AstraZeneca. These companies are continuously innovating and expanding their product portfolios to capture a larger market share[4].

Regulatory and Environmental Factors

The pharmacokinetics of Marcaine Hydrochloride can be significantly altered by factors such as hepatic or renal disease, the addition of epinephrine, and patient age. Regulatory bodies ensure that these factors are considered in the labeling and administration of the drug. For instance, the FDA label for Marcaine Hydrochloride includes detailed pharmacokinetic parameters and precautions for use in different patient populations[5].

Technological Trends

Advancements in drug delivery systems and the introduction of new local anesthetics are driving the market forward. These innovations enhance the efficacy and safety of local anesthetics, making them more appealing to healthcare providers and patients alike[3].

Regional Insights

  • North America: Expected to dominate the market due to a high number of surgical procedures.
  • Asia-Pacific: Registering the highest growth due to increasing healthcare expenditure and the number of surgeries in countries like India, China, and Brazil[3][4].

Challenges and Opportunities

Challenges

  • Supply chain disruptions and stock shortages can impact the availability of Marcaine Hydrochloride.
  • Regulatory changes and stringent approval processes can pose challenges for new market entrants.

Opportunities

  • Increasing demand for post-operative pain management.
  • Growing healthcare expenditure in developing countries.
  • Advancements in drug delivery systems offering new opportunities for market growth[3][4].

Key Takeaways

  • The global bupivacaine injection market, including Marcaine Hydrochloride, is expected to grow significantly driven by increasing surgical procedures and an aging population.
  • The 0.25% concentration of bupivacaine injection is anticipated to be the most profitable segment.
  • North America is expected to dominate the market, with the Asia-Pacific region showing the highest growth.
  • The market is influenced by technological advancements, regulatory factors, and the impact of the COVID-19 pandemic.

FAQs

1. What is the projected market size of the bupivacaine injection market by 2030?

The bupivacaine injection market is expected to reach USD 1,447 million by 2030[4].

2. Which region is expected to dominate the global bupivacaine injection market?

North America is anticipated to dominate the global bupivacaine injection market[4].

3. What are the key drivers of the bupivacaine injection market?

Key drivers include the rise in surgical procedures, an aging population, and advancements in drug delivery systems[3][4].

4. How has the COVID-19 pandemic impacted the bupivacaine injection market?

The pandemic has had a positive impact due to the increased use of local anesthesia to minimize viral transmission risks and manage post-operative pain[4].

5. What are the common concentrations of Marcaine Hydrochloride available in the market?

Common concentrations include 0.25%, 0.5%, and 0.75%[4].

Cited Sources:

  1. Cognitivemarketresearch.com: Bupivacaine Hcl Market Report 2024 (Global Edition)
  2. Drugs.com: Marcaine HCl Prices, Coupons, Copay Cards & Patient Assistance
  3. Globenewswire.com: Local Anesthesia Drugs Market Size, Share & Trends Analysis 2024-2030
  4. Globenewswire.com: Bupivacaine Injection Market to Reach USD 1447 Million by 2030
  5. Accessdata.fda.gov: Marcaine Bupivacaine Hydrochloride injection label

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