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Last Updated: December 28, 2024

MIOCHOL Drug Patent Profile


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Which patents cover Miochol, and what generic alternatives are available?

Miochol is a drug marketed by Novartis and Bausch And Lomb and is included in two NDAs.

The generic ingredient in MIOCHOL is acetylcholine chloride. There are three drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the acetylcholine chloride profile page.

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Drug patent expirations by year for MIOCHOL
Drug Prices for MIOCHOL

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Recent Clinical Trials for MIOCHOL

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SponsorPhase
University Hospital, LinkoepingN/A
Gladwin, Mark, MDPhase 1
University of PittsburghPhase 1

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US Patents and Regulatory Information for MIOCHOL

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Novartis MIOCHOL acetylcholine chloride FOR SOLUTION;OPHTHALMIC 016211-001 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Bausch And Lomb MIOCHOL-E acetylcholine chloride FOR SOLUTION;OPHTHALMIC 020213-001 Sep 22, 1993 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

MIOCHOL Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Miochol

Introduction

Miochol, an acetylcholine chloride intraocular solution, is a critical medication in ophthalmic surgeries, particularly for inducing miosis and managing intraocular pressure (IOP) spikes post-cataract surgery. This article delves into the market dynamics and financial trajectory of Miochol, highlighting its cost efficiency, market competition, and the impact of supply chain disruptions.

Cost Efficiency of Miochol

Miochol is one of the two primary parasympathomimetic medications used in ophthalmic surgeries, the other being Miostat (carbachol intraocular solution). A cost analysis revealed that Miochol is significantly more expensive than Miostat, with costs per unit of $63.72 compared to $13.08 for Miostat[1].

Cost Implications

Despite its higher cost, Miochol remains a preferred choice among many retina specialists. However, the financial implications of this preference are substantial. For instance, a surgery center that purchased 237 units of Miochol in one year spent significantly more than if they had opted for Miostat. The estimated savings from switching to Miostat would have been around $11,000 in that year alone[1].

Market Competition

Comparison with Miostat

Miostat, with its longer duration of action and lower cost, presents a compelling alternative to Miochol. However, the preference for Miochol among specialists is largely due to a lack of awareness about the differences in cost and efficacy between the two medications. This lack of awareness underscores the need for better education and cost transparency in medical decision-making[1].

Industry Trends

The pharmaceutical industry is witnessing significant shifts, particularly in the management of high-cost therapies. The trend towards more cost-effective options is driven by the need to manage financial risks and ensure sustainability. Health systems are reevaluating their formulary management processes to include more rapid and cost-sensitive decision-making, which could impact the market share of medications like Miochol[3].

Supply Chain and Availability

Current Shortages

Miochol has recently faced supply chain disruptions, with Bausch Health reporting backorders for its Miochol-E 20 milligram vials. This shortage is expected to be resolved by early August, but such disruptions can significantly impact the availability and cost of the medication[4].

Impact on Pricing and Availability

Supply chain issues can lead to price volatility and increased costs for healthcare providers. When medications are in short supply, alternative options may become more expensive, and the overall cost of care can rise. For Miochol, any prolonged shortage could exacerbate its already higher cost compared to Miostat, further tilting the financial balance in favor of the cheaper alternative[4].

Financial Trajectory

Budget Implications for Healthcare Facilities

The financial trajectory of Miochol is closely tied to its cost and the frequency of its use. Given its higher cost per unit, healthcare facilities that frequently use Miochol may see significant budget implications. Switching to a more cost-effective option like Miostat could lead to substantial savings, which could be redirected to other critical areas of healthcare[1].

Impact on Formulary Management

Health systems are increasingly focusing on formulary management to optimize drug costs and ensure financial sustainability. The inclusion of Miochol in formulary decisions must consider both the cost of the drug and the cost of service delivery. This holistic approach can help in making more informed decisions that balance clinical efficacy with financial prudence[3].

Regulatory and Market Factors

Regulatory Environment

The regulatory environment plays a crucial role in the market dynamics of pharmaceuticals. Changes in regulatory policies, such as those related to good manufacturing practices, can affect the supply and cost of medications like Miochol. Compliance with these regulations can sometimes lead to temporary shortages or increased costs[4].

Market Shifts and Trends

The pharmaceutical market is evolving, with a shift towards more complex and high-cost therapies. This trend is driven by advances in medical technology and changing patient needs. For medications like Miochol, staying competitive in this landscape requires continuous evaluation of cost, efficacy, and market demand[3].

Conclusion

Miochol, despite its clinical efficacy, faces significant challenges in terms of cost efficiency and market competition. The higher cost per unit compared to Miostat, coupled with recent supply chain disruptions, underscores the need for healthcare providers to reassess their medication choices. By understanding the market dynamics and financial trajectory of Miochol, healthcare facilities can make more informed decisions that balance clinical needs with financial sustainability.

Key Takeaways

  • Miochol is more expensive than Miostat, with costs per unit of $63.72 vs. $13.08.
  • Switching from Miochol to Miostat could result in significant cost savings for healthcare facilities.
  • Supply chain disruptions can impact the availability and cost of Miochol.
  • Health systems are focusing on formulary management to optimize drug costs.
  • Regulatory and market factors influence the cost and availability of Miochol.

FAQs

Q: What is the primary use of Miochol in ophthalmic surgeries?

A: Miochol is used to induce miosis and manage intraocular pressure (IOP) spikes post-cataract surgery.

Q: How does the cost of Miochol compare to Miostat?

A: Miochol is significantly more expensive than Miostat, with costs per unit of $63.72 compared to $13.08 for Miostat.

Q: What are the potential savings from switching from Miochol to Miostat?

A: A surgery center could save an estimated $11,000 in one year by switching from Miochol to Miostat.

Q: Are there any current supply chain issues affecting Miochol?

A: Yes, Miochol is currently facing a shortage due to backorders, with supply expected to return to normal by early August.

Q: How do regulatory factors impact the cost and availability of Miochol?

A: Regulatory factors, such as compliance with good manufacturing practices, can sometimes lead to temporary shortages or increased costs for Miochol.

Sources

  1. The Cost Efficiency of Miotics Use in Ophthalmic Surgeries - Retina Today
  2. Proceedings and Debates of the National Assembly of the First - Parliament of Guyana
  3. Strategic Directions in System Formulary, Drug Policy, and High-Cost Drugs - ASHP
  4. 9 New Drug Shortages - Becker's Hospital Review

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