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Last Updated: December 22, 2024

PROLIXIN DECANOATE Drug Patent Profile


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When do Prolixin Decanoate patents expire, and what generic alternatives are available?

Prolixin Decanoate is a drug marketed by Bristol Myers Squibb and is included in one NDA.

The generic ingredient in PROLIXIN DECANOATE is fluphenazine decanoate. There are nineteen drug master file entries for this compound. Eight suppliers are listed for this compound. Additional details are available on the fluphenazine decanoate profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Prolixin Decanoate

A generic version of PROLIXIN DECANOATE was approved as fluphenazine decanoate by FRESENIUS KABI USA on July 14th, 1987.

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Summary for PROLIXIN DECANOATE
Drug patent expirations by year for PROLIXIN DECANOATE

US Patents and Regulatory Information for PROLIXIN DECANOATE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bristol Myers Squibb PROLIXIN DECANOATE fluphenazine decanoate INJECTABLE;INJECTION 016727-001 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

PROLIXIN DECANOATE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Prolixin Decanoate

Introduction

Prolixin Decanoate, also known as fluphenazine decanoate, is a long-acting parenteral antipsychotic drug used primarily in the management of chronic schizophrenia. This article delves into the market dynamics and financial trajectory of Prolixin Decanoate, exploring its current market status, future projections, and the factors influencing its market performance.

Market Size and Growth

The global Fluphenazine Decanoate market is expected to exhibit significant growth over the forecast period from 2025 to 2031. The market size is estimated based on historical data from 2019 to 2023 and projected forward using various analytical tools and market trends[1].

Segment Analysis

The market for Fluphenazine Decanoate can be segmented based on several factors, including type, application, and geography.

Type Segment Analysis

The market is primarily segmented into acute schizophrenia and chronic schizophrenia. Chronic schizophrenia is the dominant segment due to the long-term nature of the condition and the need for prolonged parenteral neuroleptic therapy[1].

Application Segment Analysis

Prolixin Decanoate is specifically indicated for the management of patients requiring prolonged parenteral neuroleptic therapy, particularly those with chronic schizophrenia. It has not been shown effective in managing behavioral complications in patients with mental retardation[2].

Geographical Segment Analysis

The global market is divided into various regions, with different regions expected to contribute differently to the overall market growth. The region expected to dominate the global Fluphenazine Decanoate market within the forecast period is likely to be influenced by factors such as prevalence of schizophrenia, healthcare infrastructure, and regulatory environments[1].

Market Trends

Several trends are shaping the market for Prolixin Decanoate:

Increasing Prevalence of Schizophrenia

The rising prevalence of schizophrenia globally is a significant driver for the Fluphenazine Decanoate market. As the population grows and mental health awareness increases, the demand for effective antipsychotic treatments is expected to rise[1].

Advancements in Drug Delivery

The long-acting nature of Prolixin Decanoate, which can last up to four weeks, is a major advantage. This reduces the need for frequent dosing and improves patient compliance, making it a preferred option for chronic schizophrenia management[4].

Regulatory Environment

Regulatory approvals and changes in healthcare policies can significantly impact the market. For instance, the inclusion of the injectable form of fluphenazine in the World Health Organization's List of Essential Medicines highlights its importance and potential for increased adoption[4].

Drivers

Several factors are driving the growth of the Fluphenazine Decanoate market:

Effective Treatment Option

Prolixin Decanoate is a highly potent behavior modifier with a markedly extended duration of effect, making it an effective treatment option for chronic schizophrenia. Its efficacy in managing symptoms over an extended period is a key driver[2].

Patient Compliance

The long-acting nature of the drug improves patient compliance, as it reduces the frequency of dosing. This is particularly beneficial for patients with chronic conditions who may struggle with daily medication regimens[4].

Financial Incentives

Healthcare systems often favor long-acting injectable antipsychotics due to their cost-effectiveness in the long term. Despite higher initial costs, these medications can reduce overall healthcare expenditure by minimizing the need for frequent hospitalizations and emergency interventions[3].

Restraints

Despite the positive trends, there are several restraints affecting the market:

Side Effects and Adverse Reactions

Prolixin Decanoate is associated with various side effects, including movement disorders, elevated prolactin levels, and rare but serious conditions such as agranulocytosis and liver problems. These adverse reactions can limit its adoption and impact patient compliance[2][5].

Competition from Other Antipsychotics

The market for antipsychotic medications is highly competitive, with various other depot and oral antipsychotics available. This competition can affect the market share of Prolixin Decanoate[3].

Financial Implications

The financial trajectory of Prolixin Decanoate is influenced by several factors:

Revenue and CAGR

The global Fluphenazine Decanoate market is expected to grow at a significant Compound Annual Growth Rate (CAGR) from 2025 to 2031. The revenue is projected to increase due to the rising demand for effective antipsychotic treatments and the cost-effectiveness of long-acting injectables[1].

Cost-Benefit Analysis

While the initial cost of Prolixin Decanoate may be higher than some oral antipsychotics, its long-term benefits in terms of reduced hospitalizations and improved patient compliance can lead to significant cost savings for healthcare systems.

Market Attractiveness

The market attractiveness of Fluphenazine Decanoate is high due to its efficacy, long duration of action, and the growing need for antipsychotic treatments. However, this attractiveness can be tempered by the presence of side effects and competition from other medications[1].

Competitive Analysis

The competitive landscape for Fluphenazine Decanoate includes other depot and oral antipsychotics. Key competitors include:

Other Depot Antipsychotics

Medications like haloperidol decanoate, perphenazine decanoate, and paliperidone palmitate are competitors in the depot antipsychotic market. Each has its own set of advantages and disadvantages, influencing market share[4].

Generic Versions

The availability of generic versions of Prolixin Decanoate can impact the market dynamics, as generics often offer a more affordable alternative. However, the brand name and reputation of Prolixin Decanoate can still maintain a significant market presence[2].

Regional Analysis

The regional analysis of the Fluphenazine Decanoate market reveals varying levels of adoption and growth potential:

North America and Europe

These regions are expected to be significant contributors to the global market due to advanced healthcare infrastructure and high awareness of mental health conditions[1].

Asia-Pacific

This region is anticipated to show rapid growth due to increasing healthcare spending, growing population, and rising awareness of mental health issues[1].

Consumer Behavior Analysis

Consumer behavior plays a crucial role in the adoption of Prolixin Decanoate. Factors such as patient compliance, preference for long-acting treatments, and the influence of healthcare providers are key drivers.

Patient Compliance

Patients often prefer treatments that are less intrusive and require less frequent dosing, making Prolixin Decanoate a favorable option[4].

Healthcare Provider Influence

Healthcare providers play a significant role in prescribing antipsychotic medications. Their preference for long-acting injectables due to their efficacy and compliance benefits can drive the market for Prolixin Decanoate[3].

Technological Trends

Advancements in drug delivery systems and formulations are ongoing, which could impact the market for Prolixin Decanoate:

New Formulations

Research into new formulations and delivery methods could potentially offer more convenient or effective alternatives, influencing the market dynamics[1].

Digital Health Integration

The integration of digital health technologies, such as monitoring systems for patient compliance, could enhance the effectiveness of Prolixin Decanoate and other long-acting antipsychotics.

SWOT Analysis

A SWOT analysis provides a comprehensive overview of the strengths, weaknesses, opportunities, and threats facing the Fluphenazine Decanoate market.

Strengths

  • Effective treatment for chronic schizophrenia
  • Long duration of action
  • Cost-effective in the long term
  • High patient compliance

Weaknesses

  • Associated with various side effects
  • Competition from other antipsychotics
  • Higher initial cost

Opportunities

  • Growing demand for antipsychotic treatments
  • Advancements in drug delivery systems
  • Increasing healthcare spending in emerging markets

Threats

  • Regulatory changes
  • Development of new antipsychotic medications
  • Economic downturns affecting healthcare spending

Key Takeaways

  • The global Fluphenazine Decanoate market is expected to grow significantly from 2025 to 2031.
  • Chronic schizophrenia is the dominant segment driving the market.
  • The long-acting nature and efficacy of Prolixin Decanoate are key drivers.
  • Side effects and competition are significant restraints.
  • Regional analysis shows varying growth potential across different regions.
  • Consumer behavior and healthcare provider influence are crucial for market adoption.

FAQs

What is Prolixin Decanoate used for?

Prolixin Decanoate is used in the management of patients requiring prolonged parenteral neuroleptic therapy, particularly those with chronic schizophrenia[2].

What are the common side effects of Prolixin Decanoate?

Common side effects include movement disorders, elevated prolactin levels, and rare but serious conditions such as agranulocytosis and liver problems[2][5].

How long does Prolixin Decanoate last?

Prolixin Decanoate can last up to four weeks, reducing the need for frequent dosing and improving patient compliance[4].

Is Prolixin Decanoate available as a generic?

Yes, generic versions of Prolixin Decanoate may be available, which can impact the market dynamics by offering a more affordable alternative[2].

What regions are expected to dominate the global Fluphenazine Decanoate market?

North America and Europe are expected to be significant contributors, while the Asia-Pacific region is anticipated to show rapid growth[1].

Sources

  1. Cognitivemarketresearch.com: Fluphenazine Decanoate Market Report 2024 (Global Edition)
  2. Drugs.com: Prolixin Decanoate: Package Insert / Prescribing Information
  3. Journalslibrary.nihr.ac.uk: Fluphenazine decanoate [depot] and enanthate for schizophrenia
  4. Wikipedia.org: Fluphenazine
  5. HealthLink BC: Fluphenazine Decanoate - Injection

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