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Last Updated: December 22, 2024

RIFAMPIN Drug Patent Profile


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Which patents cover Rifampin, and what generic alternatives are available?

Rifampin is a drug marketed by Chartwell Molecular, Epic Pharma Llc, Hikma, Lupin Pharms, Avet Lifesciences, Fresenius Kabi Usa, Hikma Pharms, Mylan Labs Ltd, Watson Pharms Teva, and Hikma Intl Pharms. and is included in twelve NDAs.

The generic ingredient in RIFAMPIN is isoniazid; rifampin. There are five drug master file entries for this compound. Additional details are available on the isoniazid; rifampin profile page.

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Recent Clinical Trials for RIFAMPIN

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SponsorPhase
Guangdong Raynovent Biotech Co., LtdPhase 1
Ministry of Health, FrancePhase 3
Assistance Publique Hopitaux De MarseillePhase 3

See all RIFAMPIN clinical trials

Pharmacology for RIFAMPIN

US Patents and Regulatory Information for RIFAMPIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Chartwell Molecular RIFAMPIN rifampin CAPSULE;ORAL 065390-001 Mar 28, 2008 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Lupin Pharms RIFAMPIN rifampin CAPSULE;ORAL 090034-001 Aug 21, 2013 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Epic Pharma Llc RIFAMPIN rifampin CAPSULE;ORAL 064150-001 May 28, 1997 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Hikma RIFAMPIN rifampin INJECTABLE;INJECTION 064217-001 Oct 29, 1999 AP RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Lupin Pharms RIFAMPIN rifampin CAPSULE;ORAL 090034-002 Aug 21, 2013 AB RX No Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

RIFAMPIN Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Rifampin

Introduction

Rifampin, a crucial antibiotic in the treatment of tuberculosis (TB) and other bacterial infections, is experiencing significant market dynamics driven by various factors. This article delves into the current market trends, financial projections, and the key drivers influencing the rifampin market.

Market Size and Forecast

The rifampin market is substantial and growing steadily. As of 2023, the market size was valued at USD 2.2 billion and is projected to reach USD 3.2 billion by 2031, growing at a Compound Annual Growth Rate (CAGR) of 5.4% during the forecast period[3].

However, another report suggests a higher valuation, with the market size estimated at USD 35 billion in 2023 and expected to reach USD 66.24 billion by 2031, growing at a CAGR of 8.3% from 2024 to 2031[4].

Key Drivers of Market Growth

Rising Prevalence of Tuberculosis (TB)

The increasing incidence of TB, particularly in developing nations, is a major driver of the rifampin market. TB remains a global health challenge, and rifampin is a cornerstone in the multidrug regimen used to combat this disease[3][4].

Growing Cases of Leprosy and Other Infections

Rifampin is also used in treating leprosy and other bacterial infections, such as those caused by staphylococci. This broader application in clinical settings further drives demand for the drug[3][4].

Increasing Multidrug-Resistant Infections

The rise in multidrug-resistant bacterial infections, where rifampin is effective as part of combination therapies, is another significant factor. This includes the treatment of drug-resistant strains of TB[3][4].

Government and Global Health Initiatives

Public health organizations like the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC), along with national governments, are promoting initiatives to eliminate TB and other diseases. These programs often involve funding and access to critical antibiotics like rifampin[3][4].

Pharmaceutical Innovation

Advances in drug formulations and delivery mechanisms, such as fixed-dose combinations or new forms of administration, contribute to market growth by improving patient compliance and outcomes[3][4].

Increased Healthcare Access in Developing Regions

Expanding healthcare infrastructure in developing nations is improving access to essential medicines, including rifampin, further propelling market demand[3][4].

Geographical Segmentation

Asia-Pacific

The Asia-Pacific region exhibits the largest market potential, driven by the high burden of infectious diseases and increasing healthcare initiatives to combat TB. Countries like India and China are focusing on increasing access to essential medications, including rifampin[3][4].

North America and Europe

In North America, particularly the United States and Canada, and in Europe, the market is characterized by a high demand for rifampin due to the rising incidence of TB and the presence of robust healthcare infrastructures[3][4].

Middle East and Africa, and Latin America

These regions present unique challenges such as healthcare discrepancies and availability issues but also show potential due to increasing efforts to tackle infectious diseases[3][4].

Price Trends and Factors Influencing Prices

Demand from Downstream Industries

The demand from downstream industries, particularly the pharmaceutical sector, is a significant driver of rifampin prices. The rise in multidrug-resistant strains and the need for effective treatment options keep the demand high[1].

Government Policies

Government initiatives for TB control programs and policies such as price capping in countries like India can impact the market dynamics and prices of rifampin. For instance, the capping of drug prices in India led to a downfall in the pharmaceutical industry in the second half of 2023[1].

Raw Material Costs

The cost of active pharmaceutical ingredients (APIs) is a critical factor. India, a key manufacturer of rifampin, is heavily dependent on APIs from China. An increase in API prices in China directly affects the global prices of rifampin[1].

Supply Chain Disruptions

Disruptions in supply chains, such as the loss of imports and the disruption of Red Sea routes, can also have an adverse effect on the overall price trend of rifampin[1].

Financial Trajectory

Revenue Growth

The rifampin market is expected to experience steady revenue growth driven by the increasing demand for effective TB treatments and other bacterial infections. The projected CAGR of 5.4% to 8.3% indicates a robust financial trajectory for the market[3][4].

Investment Opportunities

The growing market size and the critical role of rifampin in global health initiatives make it an attractive investment opportunity. Pharmaceutical companies and investors are likely to benefit from the expanding market, especially in regions with high disease prevalence[3][4].

Challenges and Risks

Regulatory Hurdles

Regulatory changes and government policies can significantly impact the market. For example, price capping and other regulatory measures can affect the profitability of rifampin manufacturers[1].

Supply Chain Risks

Disruptions in supply chains, including the availability of raw materials and transportation issues, can pose risks to the market. The reliance on specific regions for API production adds to these risks[1].

Competitive Landscape

The pharmaceutical market is highly competitive, and rifampin manufacturers must navigate this landscape to maintain market share. Innovations in drug formulations and delivery mechanisms are crucial to staying competitive[3][4].

Conclusion

The rifampin market is poised for significant growth driven by the rising prevalence of TB, increasing multidrug-resistant infections, and government health initiatives. While the market faces challenges such as regulatory hurdles and supply chain disruptions, the overall financial trajectory is positive. As the healthcare infrastructure expands in developing regions and pharmaceutical innovations continue, the demand for rifampin is expected to remain strong.

Key Takeaways

  • The rifampin market is projected to grow from USD 2.2 billion in 2023 to USD 3.2 billion by 2031, or from USD 35 billion to USD 66.24 billion, depending on the source.
  • The rising prevalence of TB and multidrug-resistant infections are key drivers of market growth.
  • Government initiatives and pharmaceutical innovations are crucial factors in the market's expansion.
  • The Asia-Pacific region holds the largest market potential due to high disease prevalence and increasing healthcare initiatives.
  • Regulatory changes and supply chain disruptions pose significant risks to the market.

FAQs

What are the primary drivers of the rifampin market?

The primary drivers include the rising prevalence of TB, increasing multidrug-resistant infections, government health initiatives, and pharmaceutical innovations.

How is the rifampin market segmented geographically?

The market is segmented into North America, Europe, Asia-Pacific, the Middle East and Africa, and Latin America, with the Asia-Pacific region showing the largest market potential.

What are the risks associated with the rifampin market?

Regulatory hurdles, supply chain disruptions, and the competitive landscape are significant risks facing the rifampin market.

How does the cost of raw materials affect rifampin prices?

The cost of active pharmaceutical ingredients (APIs), particularly from China, directly impacts the global prices of rifampin.

What is the projected growth rate of the rifampin market?

The market is projected to grow at a CAGR of 5.4% to 8.3% from 2024 to 2031, depending on the source.

Sources

  1. Procurement Resource, "Rifampicin Price Trend, Index, News, Chart, Database".
  2. CoinUnited.io, "Rifampicin ($RIF) Price Prediction: Can $RIF Reach $5 in 2025?"
  3. Verified Market Research, "Rifampin Market Size, Share, Scope, Growth, Trends & Forecast".
  4. Market Research Intellect, "Rifampicin Market Size and Projections - Market Research Intellect".

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