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Last Updated: December 22, 2024

SORBITOL-MANNITOL Drug Patent Profile


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Which patents cover Sorbitol-mannitol, and when can generic versions of Sorbitol-mannitol launch?

Sorbitol-mannitol is a drug marketed by Hospira and Icu Medical Inc and is included in three NDAs.

The generic ingredient in SORBITOL-MANNITOL is mannitol; sorbitol. There are eighteen drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the mannitol; sorbitol profile page.

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Summary for SORBITOL-MANNITOL
US Patents:0
Applicants:2
NDAs:3
Raw Ingredient (Bulk) Api Vendors: 149
Clinical Trials: 2
What excipients (inactive ingredients) are in SORBITOL-MANNITOL?SORBITOL-MANNITOL excipients list
DailyMed Link:SORBITOL-MANNITOL at DailyMed
Drug patent expirations by year for SORBITOL-MANNITOL
Recent Clinical Trials for SORBITOL-MANNITOL

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
PfizerPhase 1
Brigitte Jolles, MDPhase 2/Phase 3

See all SORBITOL-MANNITOL clinical trials

US Patents and Regulatory Information for SORBITOL-MANNITOL

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Hospira SORBITOL-MANNITOL mannitol; sorbitol SOLUTION;IRRIGATION 080224-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Hospira SORBITOL-MANNITOL IN PLASTIC CONTAINER mannitol; sorbitol SOLUTION;IRRIGATION 017636-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Icu Medical Inc SORBITOL-MANNITOL IN PLASTIC CONTAINER mannitol; sorbitol SOLUTION;IRRIGATION 018316-001 Approved Prior to Jan 1, 1982 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

SORBITOL-MANNITOL Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Sorbitol and Mannitol

Introduction to Sorbitol and Mannitol

Sorbitol and mannitol are sugar alcohols widely used in various industries, including pharmaceuticals, food and beverages, and personal care. These substances are valued for their low-calorie content, non-cariogenic properties, and versatility in applications.

Market Size and Growth

Sorbitol Market

The global sorbitol market is a significant segment within the sugar alcohol market. In 2021, sorbitol contributed to the largest revenue share, exceeding 35% of the market, and is forecast to grow at a CAGR of 5.3% from 2022 to 2028[2].

  • Revenue Forecast: The sorbitol segment is expected to contribute substantially to the overall sugar alcohol market, which is projected to reach USD 5.13 billion by 2028 from USD 3.59 billion in 2022[2].

Mannitol Market

The mannitol market is also experiencing robust growth. In 2022, the global mannitol market was estimated to be around USD 418.65 million and is projected to reach USD 890.31 million by 2033, with a CAGR of 7.1% from 2023 to 2033[1].

  • Volume Sales: The volume sales of mannitol are expected to rise, with shipments reaching 66,998 MT in 2023, growing at a rate of 5.62% in the same year[1].

Drivers of Growth

Increasing Health Consciousness

The rising health consciousness among consumers is a key driver for both sorbitol and mannitol markets. Consumers are increasingly opting for low-calorie and natural food ingredients, which has led to a surge in demand for these sugar alcohols[1][2].

Diabetes and Obesity

The increasing incidence of diabetes and obesity is another significant factor. Mannitol, in particular, is gaining traction as a sweetener that does not significantly increase blood glucose levels, making it a preferred choice for diabetic patients[1].

Pharmaceutical Applications

Mannitol is widely used in the pharmaceutical industry as an excipient and for treating various medical conditions such as brain, kidney, and heart problems. Its application in reducing intracranial pressure and treating cerebral edema also contributes to its growing demand[1][4].

Regional Dynamics

Europe

Europe is a major market for both sorbitol and mannitol. The region, particularly countries like Germany, the U.K., and France, is experiencing high demand due to the large working population and increasing health awareness. Europe contributed the largest market share of more than 35% in 2021 and is expected to grow at a CAGR of 5.0% from 2022 to 2028[2].

Asia Pacific

The Asia Pacific region, especially China and India, is also a significant market. China is the world's leading producer of sugar alternatives and accounts for over 52.9% of the Asia Pacific market. India, with its high prevalence of diabetes and obesity, is driving the demand for alternative sweeteners like mannitol[1].

Latin America

Brazil is another key market, particularly for mannitol, due to its high rates of obesity and type 2 diabetes. The government's initiatives to limit sugar consumption have further boosted the demand for mannitol in this region[1].

Challenges and Restraints

Supply Chain Disruptions

The COVID-19 pandemic caused significant disruptions in production and supply chains, affecting the sales of both sorbitol and mannitol. However, the market is expected to recover and witness healthy growth in the upcoming years[2].

Raw Material Costs

Fluctuations in raw material costs, such as corn and sugarcane prices, can impact the production economics of these sugar alcohols. For instance, the sorbitol market in Europe faced downward pressure due to high feedstock and energy prices[3].

Price Trends

Sorbitol Price Trends

Sorbitol prices have shown mixed trends across different regions. In Asia, prices fluctuated but generally remained stable. In Europe, prices were stable due to consistent supply-demand dynamics but faced downward pressure due to global sugar surpluses and declining demands from downstream industries[3].

Mannitol Price Trends

While specific price trends for mannitol are not as detailed, its demand is driven by its applications in pharmaceuticals and food industries, which are less likely to be affected by short-term price fluctuations.

Industry Verticals

Food and Beverages

Both sorbitol and mannitol are widely used in the food and beverages sector as low-calorie sweeteners and additives. Mannitol's cooling effect makes it popular in mint-based sweets and gums[1].

Pharmaceuticals

Mannitol is extensively used in pharmaceutical formulations and for treating various medical conditions. Its diuretic properties and ability to reduce intracranial pressure make it a valuable component in medical treatments[1][4].

Personal Care

Sorbitol is used in personal care products such as toothpaste and skincare products due to its moisturizing properties and low-calorie content[2].

Key Players

The market for sorbitol and mannitol is dominated by several key players:

  • Sorbitol: Companies like Roquette Frères, Cargill, and SPI Pharma are significant players in the sorbitol market[2].
  • Mannitol: Key players include Roquette Frères Company, Cargill, SPI Pharma, Qingdao Bright Moon Seaweed Group Co., Ltd., and Merck Millipore Corporation[4].

Future Outlook

The future outlook for both sorbitol and mannitol is positive, driven by increasing health consciousness, the growing diabetic population, and expanding applications in various industries.

"The rising incidence of diabetes is underpinning growth in the mannitol market. Its application is likely to surge in the food and beverages sector as a sweetener because it does not cause a significant increase in blood glucose levels."[1]

Key Takeaways

  • The sorbitol and mannitol markets are driven by increasing health consciousness and the growing incidence of diabetes.
  • Europe and the Asia Pacific region are significant markets due to their large consumer bases and growing demand for low-calorie sweeteners.
  • The pharmaceutical industry is a major driver for mannitol, while the food and beverages sector drives demand for both sorbitol and mannitol.
  • Supply chain disruptions and raw material cost fluctuations are key challenges but are expected to stabilize in the future.

FAQs

Q: What are the primary drivers of the sorbitol and mannitol markets? A: The primary drivers include increasing health consciousness, the growing incidence of diabetes, and expanding applications in pharmaceuticals and food industries.

Q: Which regions are the largest markets for sorbitol and mannitol? A: Europe and the Asia Pacific region, particularly countries like Germany, the U.K., France, China, and India, are the largest markets.

Q: How have supply chain disruptions affected the sorbitol and mannitol markets? A: Supply chain disruptions during the COVID-19 pandemic caused short-term declines in sales, but the market is expected to recover and grow in the coming years.

Q: What are the key applications of sorbitol and mannitol? A: Sorbitol is used in food, pharmaceuticals, and personal care products, while mannitol is used in pharmaceuticals, food, and as a diuretic.

Q: Who are the key players in the sorbitol and mannitol markets? A: Key players include Roquette Frères, Cargill, SPI Pharma, and several other companies specializing in sugar alcohols.

Cited Sources

  1. Future Market Insights - Mannitol Market Size, Share, Outlook & Forecast by 2033[1]
  2. Grand View Research - Global Sugar Alcohol Market Size & Share Report, 2028[2]
  3. Procurement Resource - Sorbitol Price Trend, News, Chart, Forecast, Database[3]
  4. SNS Insider - Mannitol Market Size & Share Report Forecast 2023-2030[4]
  5. GlobeNewswire - Sugar Alcohol Market to Hit US$ 1,849.6 Million by 2033[5]

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