You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: December 22, 2024

VALSARTAN AND HYDROCHLOROTHIAZIDE Drug Patent Profile


✉ Email this page to a colleague

« Back to Dashboard


When do Valsartan And Hydrochlorothiazide patents expire, and what generic alternatives are available?

Valsartan And Hydrochlorothiazide is a drug marketed by Alembic, Amneal Pharms, Apotex Inc, Aurobindo Pharma Ltd, Lupin Ltd, Macleods Pharms Ltd, Mylan Pharms Inc, Prinston Inc, Watson Labs Teva, and Zydus Lifesciences. and is included in ten NDAs.

The generic ingredient in VALSARTAN AND HYDROCHLOROTHIAZIDE is hydrochlorothiazide; valsartan. There are thirty-two drug master file entries for this compound. Nineteen suppliers are listed for this compound. Additional details are available on the hydrochlorothiazide; valsartan profile page.

AI Research Assistant
Questions you can ask:
  • What is the 5 year forecast for VALSARTAN AND HYDROCHLOROTHIAZIDE?
  • What are the global sales for VALSARTAN AND HYDROCHLOROTHIAZIDE?
  • What is Average Wholesale Price for VALSARTAN AND HYDROCHLOROTHIAZIDE?
Summary for VALSARTAN AND HYDROCHLOROTHIAZIDE
US Patents:0
Applicants:10
NDAs:10
Finished Product Suppliers / Packagers: 18
Raw Ingredient (Bulk) Api Vendors: 3
Clinical Trials: 43
Patent Applications: 219
What excipients (inactive ingredients) are in VALSARTAN AND HYDROCHLOROTHIAZIDE?VALSARTAN AND HYDROCHLOROTHIAZIDE excipients list
DailyMed Link:VALSARTAN AND HYDROCHLOROTHIAZIDE at DailyMed
Drug patent expirations by year for VALSARTAN AND HYDROCHLOROTHIAZIDE
Recent Clinical Trials for VALSARTAN AND HYDROCHLOROTHIAZIDE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Farma de Colombia SAPhase 3
Damanhour UniversityN/A
Tehran University of Medical SciencesPhase 3

See all VALSARTAN AND HYDROCHLOROTHIAZIDE clinical trials

Pharmacology for VALSARTAN AND HYDROCHLOROTHIAZIDE

US Patents and Regulatory Information for VALSARTAN AND HYDROCHLOROTHIAZIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Watson Labs Teva VALSARTAN AND HYDROCHLOROTHIAZIDE hydrochlorothiazide; valsartan TABLET;ORAL 091519-001 Mar 21, 2013 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Mylan Pharms Inc VALSARTAN AND HYDROCHLOROTHIAZIDE hydrochlorothiazide; valsartan TABLET;ORAL 078020-002 Sep 21, 2012 AB RX No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Zydus Lifesciences VALSARTAN AND HYDROCHLOROTHIAZIDE hydrochlorothiazide; valsartan TABLET;ORAL 203000-004 Mar 15, 2019 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Watson Labs Teva VALSARTAN AND HYDROCHLOROTHIAZIDE hydrochlorothiazide; valsartan TABLET;ORAL 091519-005 Mar 21, 2013 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

VALSARTAN AND HYDROCHLOROTHIAZIDE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Valsartan and Hydrochlorothiazide

Introduction to Valsartan and Hydrochlorothiazide

Valsartan and hydrochlorothiazide is a combination medication used to treat high blood pressure (hypertension). Valsartan, an angiotensin II receptor blocker (ARB), relaxes blood vessels, while hydrochlorothiazide, a thiazide diuretic, reduces the amount of water in the body by increasing urine flow, both contributing to lowering blood pressure[5].

Market Size and Growth Projections

The global market for valsartan and hydrochlorothiazide is experiencing significant growth. As of 2023, the market size was valued at several billion dollars, with projections indicating a substantial increase by 2031. For instance, the Valsartan-Hydrochlorothiazide Sales Market is anticipated to reach USD xx billion by 2031, up from USD xx billion in 2023[3].

Compound Annual Growth Rate (CAGR)

The market is forecasted to grow at a compound annual growth rate (CAGR) of several percent over the next few years. Specifically, the global valsartan drug market, which includes valsartan and hydrochlorothiazide combinations, is expected to grow at a CAGR of 6.4% from 2024 to 2030, reaching a market size of US$ 866.2 million by 2030[4].

Market Segmentation

The market for valsartan and hydrochlorothiazide is segmented based on several factors:

Type

  • The medication is available in various forms, primarily tablets and capsules. The 80mg/12.5mg tablet segment has been particularly prominent and is expected to continue growing significantly[1].

Application

  • The primary applications are in hospitals and clinics. The hospital segment is projected to expand at a significant CAGR throughout the forecast period[1].

Geographical Regions

  • The market is segmented into regions such as North America, Europe, Asia-Pacific, Middle East & Africa, and Latin America. Each region has its own growth trends and contributing countries[1][3].

Key Drivers and Opportunities

Increased Adherence and Persistence

  • The use of fixed-dose combination (FDC) therapy, such as valsartan and hydrochlorothiazide, has been shown to increase medication adherence and persistence among patients. This can lead to better health outcomes and reduced healthcare costs[2].

Growing Prevalence of Hypertension

  • The increasing prevalence of hypertension globally is a significant driver for the market. As the population ages and lifestyle factors contribute to higher blood pressure rates, the demand for effective antihypertensive medications like valsartan and hydrochlorothiazide is expected to rise.

Cost-Effectiveness

  • FDC therapies like valsartan and hydrochlorothiazide often have a positive financial impact by reducing both prescription and total medical costs. This cost-effectiveness is an attractive factor for both patients and healthcare providers[2].

Restraints and Challenges

Regulatory Scrutiny

  • The pharmaceutical industry, including the valsartan and hydrochlorothiazide market, is subject to stringent regulatory requirements. Any issues with manufacturing quality or safety can lead to recalls and regulatory actions, impacting market growth.

Competition

  • The market is highly competitive with several key players such as Novartis, Lupin, and others. This competition can lead to pricing pressures and market share challenges[1][4].

Financial Impact

Reduced Healthcare Costs

  • Studies have shown that the use of FDC therapy like valsartan and hydrochlorothiazide can lower both prescription drug costs and total medical costs. For example, one study found that FDC cohorts had lower prescription drug costs ($1587 vs. $2050) and medical costs ($3343 vs. $3817) compared to individual component (IC) cohorts[2].

Revenue Growth

  • The market is expected to see significant revenue growth over the forecast period. The global valsartan drug market, for instance, is projected to grow from US$ 589 million in 2023 to US$ 866.2 million by 2030[4].

Regional Analysis

North America

  • North America is a significant market for valsartan and hydrochlorothiazide, driven by a high prevalence of hypertension and well-established healthcare systems.

Europe

  • Europe also represents a substantial market, with countries like Germany and the UK contributing significantly to the regional growth.

Asia-Pacific

  • The Asia-Pacific region is expected to be one of the fastest-growing markets due to the large population and increasing awareness of hypertension treatment.

Key Players and Strategies

Novartis

  • Novartis, one of the leading players, continues to focus on strengthening its product portfolio and expanding its business in the global market.

Lupin

  • Lupin and other companies are also investing in strategic models to enhance their market presence and product offerings[1].

Consumer Behavior and Adherence

Improved Adherence

  • The use of FDC therapy has been associated with improved medication adherence. A study found that 62.1% of patients using FDC had improved adherence compared to 53.0% using individual components[2].

Patient Preferences

  • Patients often prefer FDC therapies due to the convenience of taking a single pill, which can simplify their medication regimen and improve compliance.

Technological and Regulatory Trends

Innovations in Formulations

  • There is ongoing research into new formulations and delivery systems that could enhance the efficacy and patient compliance of valsartan and hydrochlorothiazide.

Regulatory Updates

  • Regulatory bodies continue to update guidelines and standards for the manufacturing and approval of antihypertensive medications, which can impact market dynamics.

Economic, Political, and Social Landscapes

Economic Factors

  • Economic stability and healthcare spending are crucial factors influencing the market. In regions with strong economic growth, there is typically higher spending on healthcare, including medications like valsartan and hydrochlorothiazide.

Political Factors

  • Government policies and healthcare reforms can significantly impact the market. For example, policies that increase access to healthcare can drive up demand for antihypertensive medications.

Social Factors

  • Public awareness campaigns about hypertension and its treatment can increase demand for medications like valsartan and hydrochlorothiazide.

Conclusion

The market for valsartan and hydrochlorothiazide is poised for significant growth driven by increasing prevalence of hypertension, improved adherence and persistence with FDC therapy, and cost-effectiveness. However, the market also faces challenges such as regulatory scrutiny and competition.

Key Takeaways

  • Market Growth: The global valsartan and hydrochlorothiazide market is expected to grow substantially by 2031.
  • CAGR: The market is forecasted to grow at a CAGR of around 6.4% from 2024 to 2030.
  • Segmentation: The market is segmented by type, application, and geographical regions.
  • Key Drivers: Increased adherence, growing prevalence of hypertension, and cost-effectiveness are key drivers.
  • Restraints: Regulatory scrutiny, competition, and pricing pressures are significant restraints.
  • Financial Impact: The market is expected to see reduced healthcare costs and significant revenue growth.

FAQs

Q: What is the primary use of valsartan and hydrochlorothiazide?

A: Valsartan and hydrochlorothiazide is used to treat high blood pressure (hypertension) by relaxing blood vessels and reducing the amount of water in the body.

Q: What is the expected market size of valsartan and hydrochlorothiazide by 2031?

A: The market is anticipated to reach several billion dollars by 2031, though exact figures vary by report.

Q: Which segment is expected to grow significantly in the valsartan and hydrochlorothiazide market?

A: The hospital segment and the 80mg/12.5mg tablet segment are expected to experience significant growth.

Q: How does the use of fixed-dose combination therapy impact patient adherence?

A: The use of FDC therapy like valsartan and hydrochlorothiazide has been shown to increase medication adherence and persistence among patients.

Q: Which companies are key players in the valsartan and hydrochlorothiazide market?

A: Key players include Novartis, Lupin, and several other pharmaceutical companies.

Sources

  1. Global Valsartan Hydrochlorothiazide Market Report 2024 Edition - Cognitivemarketresearch.com
  2. Assessment of adherence, persistence, and costs among valsartan ... - PubMed
  3. Valsartan-Hydrochlorothiazide Sales Market Size, Scope And ... - Marketresearchintellect.com
  4. Valsartan Drug - Market Size - Valuates Reports - Valuates.com
  5. Valsartan and hydrochlorothiazide (oral route) - Mayo Clinic - Mayo Clinic

More… ↓

⤷  Subscribe

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.