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Last Updated: March 26, 2025

VASERETIC Drug Patent Profile


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Which patents cover Vaseretic, and what generic alternatives are available?

Vaseretic is a drug marketed by Bausch and is included in one NDA.

The generic ingredient in VASERETIC is enalapril maleate; hydrochlorothiazide. There are twenty-seven drug master file entries for this compound. Three suppliers are listed for this compound. Additional details are available on the enalapril maleate; hydrochlorothiazide profile page.

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Summary for VASERETIC
US Patents:0
Applicants:1
NDAs:1
Finished Product Suppliers / Packagers: 1
Raw Ingredient (Bulk) Api Vendors: 134
Drug Prices: Drug price information for VASERETIC
What excipients (inactive ingredients) are in VASERETIC?VASERETIC excipients list
DailyMed Link:VASERETIC at DailyMed
Drug patent expirations by year for VASERETIC
Drug Prices for VASERETIC

See drug prices for VASERETIC

US Patents and Regulatory Information for VASERETIC

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Exclusivity Expiration
Bausch VASERETIC enalapril maleate; hydrochlorothiazide TABLET;ORAL 019221-001 Oct 31, 1986 AB RX Yes Yes ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Bausch VASERETIC enalapril maleate; hydrochlorothiazide TABLET;ORAL 019221-003 Jul 12, 1995 AB RX Yes No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Exclusivity Expiration
Showing 1 to 2 of 2 entries

Expired US Patents for VASERETIC

ApplicantTradenameGeneric NameDosageNDAApproval DatePatent No.Patent Expiration
Bausch VASERETIC enalapril maleate; hydrochlorothiazide TABLET;ORAL 019221-003 Jul 12, 1995 ⤷  Try for Free ⤷  Try for Free
Bausch VASERETIC enalapril maleate; hydrochlorothiazide TABLET;ORAL 019221-003 Jul 12, 1995 ⤷  Try for Free ⤷  Try for Free
Bausch VASERETIC enalapril maleate; hydrochlorothiazide TABLET;ORAL 019221-001 Oct 31, 1986 ⤷  Try for Free ⤷  Try for Free
Bausch VASERETIC enalapril maleate; hydrochlorothiazide TABLET;ORAL 019221-001 Oct 31, 1986 ⤷  Try for Free ⤷  Try for Free
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>Patent No.>Patent Expiration
Showing 1 to 4 of 4 entries

International Patents for VASERETIC

See the table below for patents covering VASERETIC around the world.

CountryPatent NumberTitleEstimated Expiration
Croatia P940134 PROCESS FOR THE PREPARATION OF CARBOXYALKYL DIPEPTIDE DERIVATIVES ⤷  Try for Free
Czechoslovakia 237325 PROCESSING OF CARBOXYALKYLDIPEPTIDE ⤷  Try for Free
South Africa 7906688 ⤷  Try for Free
South Korea 840005083 ⤷  Try for Free
>Country>Patent Number>Title>Estimated Expiration
Showing 1 to 4 of 4 entries

Market Dynamics and Financial Trajectory for Vasopressin in Treating Vasoplegic Shock

Introduction

Vasopressin, also known as antidiuretic hormone (ADH), is a crucial medication in the treatment of vasoplegic shock, particularly in intensive care settings. The market for vasopressin is driven by several key factors, including the increasing prevalence of sepsis and the growing number of cardiac surgeries. Here, we delve into the market dynamics and financial trajectory of vasopressin in treating vasoplegic shock.

Market Size and Growth

The global vasopressin for vasoplegic shock market has been experiencing significant growth. In 2019, the market size was USD 890.9 million, and it is projected to reach USD 2,657.9 million by 2027, exhibiting a Compound Annual Growth Rate (CAGR) of 14.8% during the forecast period[1].

Key Drivers

Increasing Prevalence of Sepsis

The rising incidence of sepsis worldwide is a major driver for the vasopressin market. For instance, according to the CDC, around 1.7 million adults in the U.S. suffer from sepsis, resulting in approximately 270,000 deaths annually. This high prevalence of sepsis cases across both developed and developing economies has surged the demand for vasopressin drugs[1].

Growing Number of Cardiac Surgeries

The increasing number of cardiac surgeries globally is another significant factor boosting the demand for vasopressin. Vasopressin is often used to manage vasoplegic syndrome after cardiac surgery, thereby improving survival chances and reducing the need for catecholamine vasopressors[1].

Market Segmentation

Application Segments

The vasopressin market is segmented into sepsis, post-cardiac surgery, and other applications. The sepsis segment holds a major share of the market and is anticipated to grow significantly due to the increasing diagnosis and prevalence of sepsis. The post-cardiac surgery segment is also growing rapidly due to the introduction of new treatment models and the rising number of cardiac surgeries[1].

Regional Analysis

North America

The North American market for vasopressin was valued at USD 561.3 million in 2019. The region's growth is driven by the increasing prevalence of sepsis and the growing number of cardiac surgeries. The FDA-approved injection product, Vasostrict, also contributes to the market growth in this region[1].

Europe

Europe is expected to experience significant growth due to strong government investments in research and development (R&D) to develop advanced treatment modules for vasoplegic shock. Key players in the region are focusing on launching novel therapeutics, such as AMOMED Pharma's arginine-vasopressin for catecholamine refractory hypotension in septic shock among COVID-19 patients[1].

Asia Pacific and Latin America

The Asia Pacific and Latin American markets are anticipated to show considerable growth due to the increasing number of manufacturers penetrating these regions. The growing healthcare expenditure and rising awareness about vasoplegic shock treatment are also driving market growth in these areas[1].

Competitive Landscape

The global vasopressin market is consolidated, with key players such as Endo International Plc. and AMOMED Pharma holding significant market shares. These companies maintain their dominance through diversified product portfolios, strong geographical presence, and robust R&D activities[1].

Financial Performance of Key Players

While the financial performance of companies like Vaso Corporation is not directly tied to the vasopressin market, it provides insight into the broader healthcare and pharmaceutical industry trends. Vaso Corporation, for example, reported a record annual revenue of $81.0 million in 2023, with a strong balance sheet and positive cash flow from operating activities. This indicates a stable financial foundation that could support investments in R&D and market expansion[5].

Challenges and Restraints

Side Effects

Despite its benefits, the use of vasopressin is associated with various side effects, which can act as a restraining factor for market growth. High doses of vasopressin can lead to severe conditions, and doses above 0.04U/min are not associated with increased effectiveness but rather with more side effects[1].

High Cost and Awareness

The high cost associated with vasopressin and other vasoconstrictor drugs can impede market growth. Additionally, the lack of awareness about the treatment options for vasoplegic shock can further challenge the market[4].

Future Outlook

The vasopressin market is expected to continue its growth trajectory driven by the increasing prevalence of sepsis and cardiac surgeries. Research and development activities aimed at improving treatment models and reducing side effects will be crucial for sustained market growth. The rise in healthcare expenditure and government initiatives will also play a significant role in expanding the market.

Key Takeaways

  • The global vasopressin for vasoplegic shock market is projected to reach USD 2,657.9 million by 2027, growing at a CAGR of 14.8%.
  • The increasing prevalence of sepsis and the growing number of cardiac surgeries are major drivers for the market.
  • The sepsis segment holds a significant share of the market and is expected to grow at a significant rate.
  • North America, Europe, and the Asia Pacific are key regions driving market growth.
  • Side effects and high costs associated with vasopressin are potential restraints on market growth.

FAQs

  1. What is the primary use of vasopressin in medical treatment? Vasopressin is primarily used to treat and prevent vasoplegic shock, particularly in intensive care settings, by increasing systemic vascular resistance and arterial pressure.

  2. What are the major drivers for the vasopressin market? The major drivers include the increasing prevalence of sepsis and the growing number of cardiac surgeries globally.

  3. Which region holds the largest share of the vasopressin market? North America holds a significant share of the vasopressin market, driven by the increasing prevalence of sepsis and cardiac surgeries in the region.

  4. What are the potential side effects of vasopressin? High doses of vasopressin can lead to severe side effects, and doses above 0.04U/min are associated with more side effects rather than increased effectiveness.

  5. Who are the key players in the vasopressin market? Key players include Endo International Plc. and AMOMED Pharma, which maintain their market dominance through diversified product portfolios and robust R&D activities.

Sources

  1. Fortune Business Insights: Vasopressin for Vasoplegic Shock Market Size & Growth [2027]
  2. Biospace: Vaso Corporation Announces Financial Results for Third Quarter 2024
  3. Vision Research Reports: Anti-hypertensive Drugs Market Size, Share, Report 2024-2033
  4. Data Bridge Market Research: Vasoconstrictor Drugs Market Drivers & Industry Opportunities By 2029
  5. Vaso Corporation: Vaso Corporation Announces Financial Results for Fourth Quarter and Full Year of 2023

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.