Drugs in ATC Class A01

Up to Top Level ATC Classes

Up to A - Alimentary tract and metabolism

Subclasses in ATC: A01 - STOMATOLOGICAL PREPARATIONS

A01A - STOMATOLOGICAL PREPARATIONS

A01 Market Analysis and Financial Projection

The ATC class A01 (Stomatological Preparations) encompasses pharmaceuticals and medical devices for treating oral diseases, including caries prevention, anti-infectives, corticosteroids, and other dental therapies. Below is an analysis of its market dynamics and patent landscape as of 2025.

---

Market Dynamics

Key Growth Drivers

• Dental Caries Prevalence:
  Over 2.3 billion people globally suffer from untreated cavities, driving demand for caries prophylactic agents like fluoride formulations (sodium fluoride, stannous fluoride)[7][8]. The dental caries market is projected to reach $9.18 billion by 2025 (CAGR: 4.67%)[3].
• Technological Advancements:
  Innovations in endodontic devices (e.g., nickel-titanium rotary files) and dental consumables like 3D-printed prosthetics boost adoption. The endodontics market alone is expected to grow to $3.25 billion by 2032 (CAGR: 3.9%)[9].
• Aging Populations and Cosmetic Dentistry:
  Demand for dental reconstruction (crowns, veneers) is rising, with the dental burs market forecast to reach $881.6 million by 2030 (CAGR: 5.5%)[7].

Regional Insights

• North America dominates due to advanced healthcare infrastructure, contributing over 35% of the global dental caries market[3].
• Asia-Pacific shows rapid growth (CAGR: 6.8% for dental adhesives) driven by medical tourism and increasing oral health awareness[11].

Challenges

• Skill Shortages: Limited availability of trained professionals in developing regions hampers market expansion[3].
• High Costs: Advanced treatments like bioactive nanocomposites and AI-driven diagnostics face adoption barriers in low-income countries[4][10].

---

Patent Landscape

Innovation Trends

• Caries Prevention:
  Sodium fluoride formulations (A01AA) lead patent activity, with combinations like sodium monofluorophosphate gaining traction[8][12]. Only 61 patents focus on pediatric dental caries, highlighting unmet needs[2].
• Material Science:
  3D printing, bioactive ceramics, and antimicrobial polymers dominate recent filings. For example, 3M’s "Dental Restorative Compositions Containing Nanoparticles" patent (2020) enhances restoration durability[4].
• Localized Treatments:
  Patents for corticosteroids (A01AC) and anti-infectives (A01AB) like chlorhexidine combinations surged by 9.3% from 2023–2024[4][6].

Geographic Distribution

• China leads in patent filings for stomatological preparations, accounting for 37% of caries-related patents[2][4].
• Europe lags, contributing just 12% of pediatric dental patents, indicating gaps in R&D investment[2].

Competitive Benchmarking

• Top Assignees: Dentsply Sirona, Nobel Biocare, and 3M lead in dental consumables, focusing on bioactive materials and minimally invasive devices[4][6].
• Technology Maturation: Dental implant patents peaked in the early 2010s, with current innovations centering on AI-driven treatment planning[6].

---

Future Outlook

• Emerging Technologies:
  AI for caries detection and bioactive resins with self-healing properties are under development[4][9].
• Market Consolidation:
  Mergers between dental tech firms and material science companies (e.g., Envista’s acquisitions) will drive vertical integration[7][9].

---

"The huge burden of dental caries in primary teeth is poorly represented in global R&D, highlighting insufficient research initiatives in Europe." [2]

This sector’s growth hinges on bridging innovation gaps in pediatric care and expanding access to cost-effective solutions in emerging markets.

---

Citations: [1][2][3][4][6][7][8][9][11]

References

1. https://en.wikipedia.org/wiki/ATC_code_A01
2. https://pubmed.ncbi.nlm.nih.gov/31238503/
3. https://www.industryarc.com/Research/Dental-Caries-Market-Research-504282
4. https://www.expertmarketresearch.com/patent-analysis/dental-consumables-patent-landscape
5. https://atcddd.fhi.no/atc_ddd_index/?code=A01A&showdescription=yes
6. https://pubmed.ncbi.nlm.nih.gov/34669245/
7. https://www.globenewswire.com/news-release/2025/03/14/3042840/28124/en/Dental-Burs-Market-Trends-Analysis-Report-2025-2030-with-Profiles-of-Dentsply-Sirona-Coltene-Shofu-MANI-Brasseler-USA-American-Orthodontics-Prima-Dental-Diatech-Komet-Dental-Envist.html
8. https://go.drugbank.com/drugs/DB09325
9. https://www.fortunebusinessinsights.com/endodontics-market-110481
10. https://www.fortunebusinessinsights.com/air-traffic-control-atc-market-102957
11. https://straitsresearch.com/report/dental-adhesives-and-sealants-market
12. https://farmaciajournal.com/wp-content/uploads/art-25-Pana_Craciun-Taerel_813-820.pdf
13. https://www.iqvia.com/-/media/iqvia/pdfs/belgium/sales-trends/2018/belgian-reg-med-best-performers-for-october-2018.pdf?la=sk-sk&hash=5F03C3AA6255CA928A6446DA47F98DC6
14. https://wipo-analytics.github.io/handbook/classification.html