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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR ACTIVASE


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All Clinical Trials for ACTIVASE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00250991 ↗ Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial Completed National Institute of Neurological Disorders and Stroke (NINDS) Phase 1/Phase 2 2003-07-01 The purpose of this study is determine the effects of using of a combination of two drugs--integrilin (eptifibatide) and activase (recombinant tissue plasminogen activator, rt-PA, or recombinant t-PA)--to dissolve blood clots in patients who have a stroke.
NCT00250991 ↗ Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial Completed University of Cincinnati Phase 1/Phase 2 2003-07-01 The purpose of this study is determine the effects of using of a combination of two drugs--integrilin (eptifibatide) and activase (recombinant tissue plasminogen activator, rt-PA, or recombinant t-PA)--to dissolve blood clots in patients who have a stroke.
NCT00265005 ↗ Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants Terminated Genentech, Inc. Phase 1 2005-06-01 The purpose of this study is to determine if alteplase is effective in dissolving a clot in a catheter in a large vein (central venous line or PICC line) or artery in infants less than 6 months of age.
NCT00265005 ↗ Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants Terminated University of Louisville Phase 1 2005-06-01 The purpose of this study is to determine if alteplase is effective in dissolving a clot in a catheter in a large vein (central venous line or PICC line) or artery in infants less than 6 months of age.
NCT00284739 ↗ Alteplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses Completed Genentech, Inc. Phase 2 2006-02-01 Intracavitary injection of low dose alteplase into loculated abdominopelvic abscesses will reduce the duration of percutaneous drainage and increase the proportion of successful drainages.
NCT00284739 ↗ Alteplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses Completed Kaiser Permanente Phase 2 2006-02-01 Intracavitary injection of low dose alteplase into loculated abdominopelvic abscesses will reduce the duration of percutaneous drainage and increase the proportion of successful drainages.
NCT00307580 ↗ Cathflo Activase Pediatric Study Completed Genentech, Inc. Phase 4 2002-04-01 This was a Phase IV, open-label, single-arm, multicenter trial that was to be conducted at ~60 sites in the United States. Approximately 300 pediatric subjects with dysfunctional CVADs (including catheters with valves, multiple lumens, umbilical catheters, and implanted ports) were to be treated with up to two serially instilled doses of Cathflo Activase.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ACTIVASE

Condition Name

Condition Name for ACTIVASE
Intervention Trials
Stroke 9
Ischemic Stroke 4
Pleural Effusion 2
Pulmonary Embolism 2
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Condition MeSH

Condition MeSH for ACTIVASE
Intervention Trials
Stroke 12
Ischemic Stroke 7
Ischemia 4
Cerebral Infarction 3
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Clinical Trial Locations for ACTIVASE

Trials by Country

Trials by Country for ACTIVASE
Location Trials
United States 170
Australia 10
Canada 10
China 6
Spain 5
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Trials by US State

Trials by US State for ACTIVASE
Location Trials
California 11
Ohio 10
Pennsylvania 8
Illinois 8
New York 7
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Clinical Trial Progress for ACTIVASE

Clinical Trial Phase

Clinical Trial Phase for ACTIVASE
Clinical Trial Phase Trials
Phase 4 3
Phase 3 10
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for ACTIVASE
Clinical Trial Phase Trials
Completed 15
Terminated 6
Withdrawn 3
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Clinical Trial Sponsors for ACTIVASE

Sponsor Name

Sponsor Name for ACTIVASE
Sponsor Trials
Genentech, Inc. 14
National Institute of Neurological Disorders and Stroke (NINDS) 5
Johns Hopkins University 3
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Sponsor Type

Sponsor Type for ACTIVASE
Sponsor Trials
Other 50
Industry 22
NIH 7
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