Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
Completed
Amgen
Phase 2
2005-01-01
The purpose of this study is to determine if palifermin will reduce the incidence of
dysphagia in patients receiving concurrent chemoradiotherapy followed by consolidation
chemotherapy for treatment of unresectable stage III Non-Small Cell Lung Cancer (NSCLC).
Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
Completed
Swedish Orphan Biovitrum
Phase 2
2005-01-01
The purpose of this study is to determine if palifermin will reduce the incidence of
dysphagia in patients receiving concurrent chemoradiotherapy followed by consolidation
chemotherapy for treatment of unresectable stage III Non-Small Cell Lung Cancer (NSCLC).
Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer
Completed
Amgen
Phase 3
2005-08-01
The purpose of this research study is to test the safety and effectiveness of palifermin to
determine if weekly doses can be safely administered to reduce the incidence (occurrence of),
duration (length of time) and severity (amount of pain) of oral mucositis (painful sores in
the mouth). Mucositis is a common side effect for patients receiving chemotherapy
(cancer-killing drug) and radiotherapy (cancer-killing x-rays) for the treatment of head and
neck cancer (HNC).
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