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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR ORENCIA


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All Clinical Trials for ORENCIA

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00035529 ↗ A Study to Evaluate the Preliminary Efficacy Pharmacokinetics and Immunogenicity of BMS-188667 Administered to Subjects With Relapsing-remitting Multiple Sclerosis Terminated Bristol-Myers Squibb Phase 2 2001-11-01 The purpose of this study is to determine whether BMS-188667 will decrease multiple sclerosis disease activity on MRI examinations, as well as decrease the rate of clinical MS exacerbations, compared to placebo
NCT00048581 ↗ Phase III Study of BMS-188667 (CTLA4Ig) in Patients With Rheumatoid Arthritis Who Are Currently Failing Anti-TNF Therapy or Who Have Failed Anti-TNF Therapy in the Past. Completed Bristol-Myers Squibb Phase 3 2002-12-01 The purpose of this clinical research study is to determine whether abatacept treatment on a background of Disease Modifying Antirheumatic Drugs (DMARDs) will relieve the symptoms of rheumatoid arthritis (RA) in participants who are currently receiving anti-tumor necrosis factor (TNF) therapy for at least 3 months and are not responding or have taken anti-TNF therapy in the last 3 months and did not respond. The safety of treatment with abatacept will also be evaluated. This study also has a 4.5-year long-term extension beginning 6 months after the start of the study.
NCT00048932 ↗ A Phase III Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis Completed Bristol-Myers Squibb Phase 3 2002-12-01 The purpose of this clinical research study is to learn if abatacept is safe when co-administered with other approved rheumatoid arthritis medications.
NCT00095147 ↗ Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis Completed Bristol-Myers Squibb Phase 3 2005-02-01 The purpose of this clinical research study is to learn if Abatacept or Infliximab in combination with Methotrexate demonstrate a greater reduction in disease activity over placebo.
NCT00095173 ↗ BMS-188667 in Children and Adolescents With Juvenile Rheumatoid Arthritis Completed Bristol-Myers Squibb Phase 3 2003-12-01 The primary purpose of the clinical research study is to assess the safety of treating children and juvenile subjects with BMS-188667 (Abatacept). In addition, the study will assess the effectiveness of BMS-188667 in reducing disease activity of Juvenile Rheumatoid Arthritis (JRA) or Juvenile Idiopathic Arthritis (JIA) as measured by the time to occurrence of disease flare.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ORENCIA

Condition Name

Condition Name for ORENCIA
Intervention Trials
Rheumatoid Arthritis 39
Rheumatoid Arthritis (RA) 4
Arthritis, Rheumatoid 3
Graft Vs Host Disease 3
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Condition MeSH

Condition MeSH for ORENCIA
Intervention Trials
Arthritis 53
Arthritis, Rheumatoid 49
Graft vs Host Disease 6
Lupus Erythematosus, Systemic 4
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Clinical Trial Locations for ORENCIA

Trials by Country

Trials by Country for ORENCIA
Location Trials
United States 529
Mexico 67
Canada 60
Brazil 44
Australia 36
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Trials by US State

Trials by US State for ORENCIA
Location Trials
New York 29
California 27
Pennsylvania 27
Massachusetts 27
Ohio 24
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Clinical Trial Progress for ORENCIA

Clinical Trial Phase

Clinical Trial Phase for ORENCIA
Clinical Trial Phase Trials
Phase 4 16
Phase 3 26
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for ORENCIA
Clinical Trial Phase Trials
Completed 49
Recruiting 23
Terminated 10
[disabled in preview] 12
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Clinical Trial Sponsors for ORENCIA

Sponsor Name

Sponsor Name for ORENCIA
Sponsor Trials
Bristol-Myers Squibb 67
Emory University 5
National Institute of Allergy and Infectious Diseases (NIAID) 4
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Sponsor Type

Sponsor Type for ORENCIA
Sponsor Trials
Other 94
Industry 75
NIH 10
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