CLINICAL TRIALS PROFILE FOR SEROSTIM

All Clinical Trials for SEROSTIM

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00071240 ↗	Growth Hormone to Increase Immune Function in People With HIV	Completed	EMD Serono	Phase 2	2002-10-01	Growth hormone plays an important role in the development of the immune system. Studies suggest that growth hormone may promote growth of the thymus, a gland responsible for the production of important immune cells called T cells. Since these cells are lost during the course of HIV infection, it is possible that growth hormone treatment could help restore the immune system. This study will determine whether the administration of growth hormone can increase the size and function of the thymus and cause an increase in the number of new T cells in the blood of people infected with HIV. Study hypothesis: Growth hormone treatment will enhance T cell production in HIV infected adults.
NCT00071240 ↗	Growth Hormone to Increase Immune Function in People With HIV	Completed	National Center for Research Resources (NCRR)	Phase 2	2002-10-01	Growth hormone plays an important role in the development of the immune system. Studies suggest that growth hormone may promote growth of the thymus, a gland responsible for the production of important immune cells called T cells. Since these cells are lost during the course of HIV infection, it is possible that growth hormone treatment could help restore the immune system. This study will determine whether the administration of growth hormone can increase the size and function of the thymus and cause an increase in the number of new T cells in the blood of people infected with HIV. Study hypothesis: Growth hormone treatment will enhance T cell production in HIV infected adults.
NCT00071240 ↗	Growth Hormone to Increase Immune Function in People With HIV	Completed	The J. David Gladstone Institutes	Phase 2	2002-10-01	Growth hormone plays an important role in the development of the immune system. Studies suggest that growth hormone may promote growth of the thymus, a gland responsible for the production of important immune cells called T cells. Since these cells are lost during the course of HIV infection, it is possible that growth hormone treatment could help restore the immune system. This study will determine whether the administration of growth hormone can increase the size and function of the thymus and cause an increase in the number of new T cells in the blood of people infected with HIV. Study hypothesis: Growth hormone treatment will enhance T cell production in HIV infected adults.
NCT00071240 ↗	Growth Hormone to Increase Immune Function in People With HIV	Completed	University of California, San Francisco	Phase 2	2002-10-01	Growth hormone plays an important role in the development of the immune system. Studies suggest that growth hormone may promote growth of the thymus, a gland responsible for the production of important immune cells called T cells. Since these cells are lost during the course of HIV infection, it is possible that growth hormone treatment could help restore the immune system. This study will determine whether the administration of growth hormone can increase the size and function of the thymus and cause an increase in the number of new T cells in the blood of people infected with HIV. Study hypothesis: Growth hormone treatment will enhance T cell production in HIV infected adults.
NCT00071240 ↗	Growth Hormone to Increase Immune Function in People With HIV	Completed	National Institute of Allergy and Infectious Diseases (NIAID)	Phase 2	2002-10-01	Growth hormone plays an important role in the development of the immune system. Studies suggest that growth hormone may promote growth of the thymus, a gland responsible for the production of important immune cells called T cells. Since these cells are lost during the course of HIV infection, it is possible that growth hormone treatment could help restore the immune system. This study will determine whether the administration of growth hormone can increase the size and function of the thymus and cause an increase in the number of new T cells in the blood of people infected with HIV. Study hypothesis: Growth hormone treatment will enhance T cell production in HIV infected adults.
NCT00082628 ↗	Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients	Completed	EMD Serono	Phase 3	2004-05-28	The primary objective of the study is to determine if Serostim® 4 mg administered daily for 12 weeks as treatment for the abnormal fat accumulation and distribution associated with HIV-associated Adipose Redistribution Syndrome (HARS) reduces Visceral Adipose Tissue (VAT, measured by CT scan) more effectively than placebo.

Clinical Trial Conditions for SEROSTIM

Condition Name

Condition Name for SEROSTIM
Intervention	Trials
HIV Infections	5
Human Immunodeficiency Virus Infections	2
Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS)	2
HIV-Associated Lipodystrophy Syndrome	1

Condition MeSH

Condition MeSH for SEROSTIM
Intervention	Trials
HIV Infections	7
Syndrome	3
Lipodystrophy	3
Immunologic Deficiency Syndromes	3

Clinical Trial Locations for SEROSTIM

Trials by Country

Trials by Country for SEROSTIM
Location	Trials
United States	19
Canada	1

Trials by US State

Trials by US State for SEROSTIM
Location	Trials
New York	4
California	2
Massachusetts	2
Indiana	1
Illinois	1

Clinical Trial Progress for SEROSTIM

Clinical Trial Phase

Clinical Trial Phase for SEROSTIM
Clinical Trial Phase	Trials
Phase 3	2
Phase 2/Phase 3	2
Phase 2	1

Clinical Trial Status

Clinical Trial Status for SEROSTIM
Clinical Trial Phase	Trials
Completed	7
Enrolling by invitation	1
Active, not recruiting	1

Clinical Trial Sponsors for SEROSTIM

Sponsor Name

Sponsor Name for SEROSTIM
Sponsor	Trials
EMD Serono	5
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	2
Massachusetts General Hospital	1

Sponsor Type

Sponsor Type for SEROSTIM
Sponsor	Trials
Other	6
Industry	5
NIH	4