CLINICAL TRIALS PROFILE FOR XIAFLEX
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All Clinical Trials for XIAFLEX
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00261196 ↗ | Collagenase in the Treatment of Adhesive Capsulitis (Frozen Shoulder) | Withdrawn | Biospecifics Technologies Corp. | Phase 2 | 2006-01-01 | The purpose of this study is to test collagenase injection therapy to dissolve adhesions causing frozen shoulder. |
| NCT00261196 ↗ | Collagenase in the Treatment of Adhesive Capsulitis (Frozen Shoulder) | Withdrawn | Stony Brook University | Phase 2 | 2006-01-01 | The purpose of this study is to test collagenase injection therapy to dissolve adhesions causing frozen shoulder. |
| NCT01237964 ↗ | Injectable Collagenase For Burns' Associated Contracture | Unknown status | Sheba Medical Center | Phase 2 | 2011-03-01 | A pilot experiment to test the efficiency of the enzyme Collagenase in treating contractures which result's from burn's healing process. So far, treatment of choice in patients with burn's created movement limiting contractures, concentrated around supportive care. Patients were referred to surgical intervention only if necessary. Treatment by injecting an external enzyme is avant-garde and hasn't been done under such conditions. This study might introduce a new kind of treatment, which can be done in ambulatory environment .This type of treatment might significantly improve patients' function and quality of life, with no need for a surgical intervention. |
| NCT01613313 ↗ | A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma | Completed | Advance Biofactures Corporation | Phase 2 | 2012-05-01 | The purpose of this research is to evaluate the safest and most effective dose of a Food and Drug Administration (FDA) approved drug (XIAFLEX) in the treatment of lipoma (fatty tumors of varying sizes that occur commonly in the adult population). The fat in the lipoma is like normal fat except that it is enclosed in a balloon-like structure which is made of collagen (fibrous tissue). Treatment of the lipoma with an injection of XIAFLEX (a protein that breaks down collagen fibers) may dissolve the collagen/fibrous strands thereby decreasing the size of the lipoma or removing it. |
| NCT01613313 ↗ | A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma | Completed | Zachary Gerut | Phase 2 | 2012-05-01 | The purpose of this research is to evaluate the safest and most effective dose of a Food and Drug Administration (FDA) approved drug (XIAFLEX) in the treatment of lipoma (fatty tumors of varying sizes that occur commonly in the adult population). The fat in the lipoma is like normal fat except that it is enclosed in a balloon-like structure which is made of collagen (fibrous tissue). Treatment of the lipoma with an injection of XIAFLEX (a protein that breaks down collagen fibers) may dissolve the collagen/fibrous strands thereby decreasing the size of the lipoma or removing it. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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