A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take Zidovudine
Completed
Hoffmann-La Roche
Phase 2
1969-12-31
To compare the safety, tolerance, and efficacy of saquinavir mesylate (Ro 31-8959) alone,
zalcitabine (dideoxycytidine; ddC) alone, and both in combination, in patients discontinuing
or unable to take zidovudine (AZT).
A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment
Completed
Hoffmann-La Roche
Phase 3
1969-12-31
To compare, in zidovudine (AZT)-naive patients, the safety, tolerance, and efficacy of
saquinavir mesylate (Ro 31-8959) alone versus AZT alone versus AZT in combination with Ro
31-8959, zalcitabine (ddC), or both. To compare various disease markers among the different
regimens.
Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?
Completed
British Heart Foundation
Phase 2
2005-04-01
Patients with kidney failure have a poor survival rate that is due to a much higher than
average rate of heart and vascular disease. The reason that kidney failure causes heart
disease is unknown but recent research suggests that a hormone called aldosterone, which is
increased in patients with kidney disease may damage the heart and blood vessels.
The investigators propose, using a randomized blinded trial, to find out whether drugs that
inhibit the actions of aldosterone have beneficial effects on the cardiovascular system in
patients with kidney failure
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.