CLINICAL TRIALS PROFILE FOR BEVACIZUMAB
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Biosimilar Clinical Trials for bevacizumab
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT02069704 ↗ | Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients | Completed | Laboratorio Elea Phoenix S.A. | Phase 1 | 2014-10-29 | This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care. |
NCT02069704 ↗ | Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients | Completed | Laboratorio Elea S.A.C.I.F. y A. | Phase 1 | 2014-10-29 | This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care. |
NCT02069704 ↗ | Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients | Completed | Libbs Farmacêutica LTDA | Phase 1 | 2014-10-29 | This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care. |
NCT02069704 ↗ | Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients | Completed | mAbxience S.A | Phase 1 | 2014-10-29 | This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
All Clinical Trials for bevacizumab
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00006786 ↗ | Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer | Completed | National Cancer Institute (NCI) | Phase 2 | 2000-11-01 | RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bevacizumab may stop the growth of colorectal cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus bevacizumab in treating patients who have advanced colorectal cancer. |
NCT00006786 ↗ | Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer | Completed | Eastern Cooperative Oncology Group | Phase 2 | 2000-11-01 | RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bevacizumab may stop the growth of colorectal cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus bevacizumab in treating patients who have advanced colorectal cancer. |
NCT00015951 ↗ | Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers | Completed | National Cancer Institute (NCI) | Phase 2 | 2001-04-01 | RATIONALE: Monoclonal antibodies such as bevacizumab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may be an effective treatment for hematologic cancer. PURPOSE: Phase II trial to study the effectiveness of bevacizumab combined with cytarabine and mitoxantrone in treating patients who have hematologic cancer. |
NCT00015951 ↗ | Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers | Completed | University of Maryland Greenebaum Cancer Center | Phase 2 | 2001-04-01 | RATIONALE: Monoclonal antibodies such as bevacizumab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may be an effective treatment for hematologic cancer. PURPOSE: Phase II trial to study the effectiveness of bevacizumab combined with cytarabine and mitoxantrone in treating patients who have hematologic cancer. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for bevacizumab
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Clinical Trial Locations for bevacizumab
Trials by Country
Clinical Trial Progress for bevacizumab
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Clinical Trial Sponsors for bevacizumab
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