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Last Updated: December 15, 2024

CLINICAL TRIALS PROFILE FOR OCRIPLASMIN


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All Clinical Trials for ocriplasmin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00412451 ↗ A Multicenter Study to Compare Multiple Doses of Intravitreal Microplasmin Versus Sham Injection for Treatment of Patients With Diabetic Macular Edema (DME) Completed ThromboGenics Phase 2 2006-12-01 A multicenter study to compare multiple doses of intravitreal microplasmin for non-surgical PVD induction for treatment of patients with DME.
NCT00435539 ↗ A Study to Compare Multiple Doses Intravitreal Microplasmin for Treatment of Patients With Vitreomacular Traction (MIVI-IIt) Completed ThromboGenics Phase 2 2007-02-01 A multicenter study to compare multiple doses of intravitreal microplasmin for non-surgical PVD induction for treatment of patients with vitreomacular traction.
NCT00913744 ↗ Safety and Efficacy Study of Intravitreal Ocriplasmin in Subjects With AMD With Focal Vitreomacular Adhesion Completed ThromboGenics Phase 2 2010-01-01 This study will evaluate the safety and efficacy of Ocriplasmin intravitreal injection, in subjects diagnosed with exudative AMD with focal vitreomacular adhesion. Ultimately, it is believed that intravitreal ocriplasmin may offer physicians a safe agent for pharmacologic vitreolysis and nonsurgical resolution of focal vitreomacular adhesion in AMD subjects where this adhesion may be causally associated with worse prognosis).
NCT00986362 ↗ Clinical Trial of Intravitreal Microplasmin in Infants and Children Scheduled for Vitrectomy Completed ThromboGenics Phase 2 2010-02-01 To evaluate the safety and preliminary efficacy of intravitreal microplasmin as an adjunct to conventional vitrectomy for the treatment of pediatric patients.
NCT01159665 ↗ The Purpose of This Study is to Evaluate the Pharmacokinetic Properties of Intravitreal Ocriplasmin Prior to Planned Primary Pars Plana Vitrectomy (PPV) Completed ThromboGenics Phase 2 2010-07-01 To evaluate the pharmacokinetic properties of intravitreal ocriplasmin 125 µg dose when administered at different time-points prior to planned primary pars plana vitrectomy (PPV)
NCT01287988 ↗ Follow-up Study to Assess Visual Function in Subset of Patients Who Have Previously Participated in the TG-MV-006 and TG-MV-007 Ocriplasmin Studies Completed ThromboGenics 2011-05-01 The primary objective of this study is to assess visual function in up to 44 patients who have previously participated in either of the placebo controlled, ocriplasmin Phase III studies (TG-MV-006 or TG-MV-007).
NCT01429441 ↗ Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole Completed ThromboGenics Phase 3 2011-10-01 The purpose of this study is to evaluate the treatment of symptomatic vitreomacular adhesion / (VMT) including macular hole with ocriplasmin.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ocriplasmin

Condition Name

Condition Name for ocriplasmin
Intervention Trials
Vitreomacular Traction 4
Symptomatic Vitreomacular Adhesion 2
Vitrectomy 2
Vitreomacular Adhesion 2
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Condition MeSH

Condition MeSH for ocriplasmin
Intervention Trials
Tissue Adhesions 6
Vitreous Detachment 3
Retinal Vein Occlusion 1
Macular Degeneration 1
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Clinical Trial Locations for ocriplasmin

Trials by Country

Trials by Country for ocriplasmin
Location Trials
United States 35
Germany 6
Belgium 6
United Kingdom 5
Italy 3
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Trials by US State

Trials by US State for ocriplasmin
Location Trials
Texas 5
Michigan 3
Florida 3
California 3
Virginia 2
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Clinical Trial Progress for ocriplasmin

Clinical Trial Phase

Clinical Trial Phase for ocriplasmin
Clinical Trial Phase Trials
Phase 4 2
Phase 3 2
Phase 2 7
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Clinical Trial Status

Clinical Trial Status for ocriplasmin
Clinical Trial Phase Trials
Completed 11
Terminated 2
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Clinical Trial Sponsors for ocriplasmin

Sponsor Name

Sponsor Name for ocriplasmin
Sponsor Trials
ThromboGenics 9
Alcon Research 3
Universitaire Ziekenhuizen Leuven 1
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Sponsor Type

Sponsor Type for ocriplasmin
Sponsor Trials
Industry 12
Other 4
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