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Last Updated: April 26, 2025

Aldesleukin - Biologic Drug Details


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Summary for aldesleukin
Recent Clinical Trials for aldesleukin

Identify potential brand extensions & biosimilar entrants

SponsorPhase
University of Southern CaliforniaPhase 1
James Isaacs, MDPhase 1
NeogenTCPhase 1

See all aldesleukin clinical trials

Recent Litigation for aldesleukin

Identify key patents and potential future biosimilar entrants

District Court Litigation
Case NameDate
JAZZ PHARMACEUTICALS IRELAND LIMITED v. LUPIN LTD.2023-01-19
JAZZ PHARMACEUTICALS IRELAND LIMITED v. LUPIN INC.2021-07-28
Amgen Inc. v. Accord Healthcare, Inc.2018-06-28

See all aldesleukin litigation

PTAB Litigation
PetitionerDate
2012-09-25

See all aldesleukin litigation

Pharmacology for aldesleukin
Physiological EffectIncreased Lymphocyte Activation
Increased Lymphocyte Cell Production
Established Pharmacologic ClassLymphocyte Growth Factor
Chemical StructureInterleukin-2
Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for aldesleukin Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for aldesleukin Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for aldesleukin Derived from Patent Text Search

No patents found based on company disclosures

Market Dynamics and Financial Trajectory for the Biologic Drug: Aldesleukin

Introduction to Aldesleukin

Aldesleukin, also known as interleukin-2 (IL-2), is a biologic drug that plays a crucial role in boosting the body's immune response. It is primarily used in the treatment of various types of cancer, including melanoma and renal cell carcinoma, by helping the immune system identify and attack cancer cells[1][4].

Market Size and Projection

The global Aldesleukin market is experiencing significant growth, driven by several key factors. As of 2024, the market was valued at approximately $160.3 million and is projected to grow at a compound annual growth rate (CAGR) of 4.0% to reach $228.9 million by 2034[4].

Drivers of Market Growth

Increasing Prevalence of Cancer

The rising prevalence of cancer worldwide is a major driver of the Aldesleukin market. The geriatric population, which is at a higher risk of developing cancer, is growing rapidly, thereby increasing the demand for cancer treatments like Aldesleukin[4].

Advancements in Immunotherapy

The increasing adoption of immunotherapy as a first-line treatment for cancer is another significant factor. Aldesleukin's effectiveness in treating advanced renal cell carcinoma and melanoma has made it a key player in the immunotherapy landscape[1][4].

Combination Therapies

The development of combination therapies that pair Aldesleukin with other immunotherapeutic agents, such as immune checkpoint inhibitors, is a major trend. These therapies aim to produce synergistic effects, leading to better clinical outcomes and improved survival rates for patients with advanced cancers[1].

Personalized Medicine

The rise of personalized medicine is also driving the market. Aldesleukin can be tailored to enhance the immune response based on a patient’s specific genetic makeup, ensuring more effective and targeted therapies[1].

Regulatory Approvals and New Indications

The approval of new indications for Aldesleukin and the increasing focus on personalized medicine are contributing to its growing market share. Recent agreements and clinical trials, such as the Phase III study for HIV patients and the Phase II trial for Amyotrophic Lateral Sclerosis, further indicate the drug's expanding therapeutic uses[4].

Market Segmentation

The Aldesleukin market is segmented based on several criteria:

Type

  • The market is segmented into injection and powder forms, catering to different administration needs and patient preferences[4].

Application

  • Aldesleukin is used in various settings, including hospitals and pharmacies, reflecting its widespread adoption in healthcare[4].

Region

  • The market is segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa, highlighting regional variations in demand and market penetration[4].

Competitive Landscape

The Aldesleukin market is characterized by the presence of prominent players involved in the development and commercialization of Aldesleukin-based therapies. These companies are investing heavily in research and development to capitalize on the growing demand for immunotherapies. Recent collaborations, mergers, and acquisitions are also shaping the market landscape[4].

Financial Trajectory

Current Market Value

  • As of 2024, the Aldesleukin market was valued at $160.3 million[4].

Projected Growth

  • The market is expected to grow at a CAGR of 4.0% to reach $228.9 million by 2034[4].

Investment and Funding

  • The increasing interest in immunotherapies has attracted significant investment from healthcare providers and pharmaceutical companies. This investment is driving the development of new Aldesleukin-based therapies and enhancing market penetration[1].

Innovations and Trends

Advanced Drug Formulations

  • The development of novel Aldesleukin-based therapies in combination with other immunotherapies is a key trend. These advancements aim to improve efficacy while minimizing side effects, making treatment more tolerable for patients[1].

Clinical Trials and Research

  • Ongoing research and clinical trials, such as the Phase III study for HIV patients and the Phase II trial for Amyotrophic Lateral Sclerosis, are expanding the therapeutic indications of Aldesleukin. These studies indicate a promising future for the drug in treating a broader range of conditions[4].

Impact on the Biologics Market

Aldesleukin is part of the larger biologics market, which is expected to reach $699.5 billion by 2032, growing at a CAGR of 7.8% from 2024 to 2032. The biologics market is driven by factors such as the rising prevalence of chronic diseases, continuous technological advancements, and the growing adoption of biosimilars[3].

Key Takeaways

  • The Aldesleukin market is driven by the increasing prevalence of cancer, advancements in immunotherapy, and the development of combination therapies.
  • The market is projected to grow at a CAGR of 4.0% from 2024 to 2034.
  • Personalized medicine and new regulatory approvals are significant factors contributing to the market's growth.
  • The competitive landscape is characterized by prominent players investing in research and development.
  • The biologics market, of which Aldesleukin is a part, is expected to see substantial growth due to technological advancements and increasing demand.

FAQs

What is Aldesleukin used for?

Aldesleukin is primarily used to treat various types of cancer, including melanoma and renal cell carcinoma, by boosting the body's immune response.

What drives the growth of the Aldesleukin market?

The growth of the Aldesleukin market is driven by the increasing prevalence of cancer, advancements in immunotherapy, the development of combination therapies, and the rise of personalized medicine.

What is the projected market value of Aldesleukin by 2034?

The Aldesleukin market is projected to reach $228.9 million by 2034, growing at a CAGR of 4.0% from 2024.

How does Aldesleukin fit into the broader biologics market?

Aldesleukin is part of the biologics market, which is expected to reach $699.5 billion by 2032. The biologics market is driven by factors such as the rising prevalence of chronic diseases and continuous technological advancements.

What are some of the recent innovations in Aldesleukin-based therapies?

Recent innovations include the development of combination therapies with immune checkpoint inhibitors and new drug formulations aimed at improving efficacy and reducing side effects.

Sources

  1. Market Research Intellect: "Aldesleukin Market Size And Projection - Market Research Intellect"
  2. NCBI: "Radiotherapy and High-Dose Interleukin-2: Clinical and ... - NCBI"
  3. Biospace: "Biologics Market Size to Reach USD 699.5 Billion by 2032, Impelled ..."
  4. Prophecy Market Insights: "Aldesleukin Market is projected to grow at a CAGR of 4.0% to reach US$ 228.9 million by 2034"
  5. ASCO Publications: "Management of Metastatic Clear Cell Renal Cell Carcinoma"

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