Fibrin sealant patch - Biologic Drug Details

Summary for fibrin sealant patch

Tradenames:	2
High Confidence Patents:	0
Applicants:	2
BLAs:	2
Suppliers: see list	3

Pharmacology for fibrin sealant patch

Physiological Effect	Increased Coagulation Activity Increased Coagulation Factor Activity
Established Pharmacologic Class	Human Blood Coagulation Factor
Chemical Structure	Blood Coagulation Factors

Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

1. Brand-side disclosures in response to biosimilar applications

These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

2. General brand-side disclosures

These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

3. Patents from broad patent text search

For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for fibrin sealant patch Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for fibrin sealant patch Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for fibrin sealant patch Derived from Patent Text Search

No patents found based on company disclosures

Fibrin sealant patch Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Fibrin Sealant Patches

Introduction to Fibrin Sealant Patches

Fibrin sealant patches are biologic medical devices used to promote hemostasis and seal tissues during surgical procedures. These patches are composed of biocompatible materials that dissolve over time, making them a crucial tool in modern surgery.

Market Size and Growth

The global fibrin sealant patch market is experiencing significant growth, driven by several key factors. As of 2022, the market was valued at approximately $0.55 billion and is projected to reach $1.1 billion by 2032, exhibiting a Compound Annual Growth Rate (CAGR) of 7.8% from 2023 to 2032[2].

Key Market Drivers

Increasing Number of Surgical Procedures

The rise in the number of surgical procedures globally is a major driver for the fibrin sealant patch market. With an estimated 17.2 million ambulatory hospital visits or inpatient stays requiring invasive, therapeutic surgery in the United States alone in 2014, the demand for effective hemostatic agents is on the rise[1].

Growing Geriatric Population

The increasing geriatric population, prone to injuries and surgeries, coupled with the growth in prevalence of chronic diseases, is another significant driver. This demographic shift is leading to a higher number of surgical interventions, thereby boosting the demand for fibrin sealant patches[2][4].

Advancements in Surgical Techniques

Advancements in surgical techniques, particularly the growing preference for minimally invasive surgeries, are driving the adoption of fibrin sealant patches. These patches are ideal for such procedures due to their ease of use and effectiveness in controlling bleeding[4].

Market Segmentation

Dosage Form

The patch segment holds the highest market share in the fibrin sealants market, accounting for more than half of the revenue in 2022. This is due to the high adoption of patch fibrin sealants in general surgeries[2].

Application

General surgery is the leading application segment, accounting for almost one-third of the fibrin sealants market revenue. Other significant application areas include cardiovascular surgery, wound management, orthopedic surgery, and urological surgeries[2].

End User

Hospitals are the primary end users, holding a major share of the global fibrin sealant patch market due to the high requirement of hemostatic patches during surgeries[1].

Regional Analysis

North America

North America dominates the fibrin sealant patch market, driven by a well-established healthcare infrastructure, high adoption rates of advanced surgical technologies, and a significant number of surgical procedures performed annually. The U.S. is a key market due to its high healthcare expenditure and favorable reimbursement policies[3][4].

Asia-Pacific

The Asia-Pacific region is anticipated to experience the fastest growth rate, driven by the rapidly expanding healthcare sector, increasing investments in healthcare infrastructure, and a growing patient population. Countries like China, Japan, and India are at the forefront of this growth[4].

Challenges and Restraints

High Cost and Availability of Alternatives

The high cost of fibrin sealant patches compared to traditional hemostatic products is a significant restraint. Additionally, the availability of alternative products further complicates the market dynamics[1][2].

Risk of Anaphylaxis and Disease Transmission

The risk of anaphylactic reactions and the transmission of viral and/or prion diseases due to the use of human pooled plasma in fibrin sealant patches are critical concerns that could hinder market growth[1].

Technological Advancements and Future Trends

Next-Generation Bioengineered Sealants

The development of next-generation bioengineered sealants with enhanced biocompatibility and efficacy is a promising trend. These advancements are expected to improve patient outcomes and reduce surgery-related complications[4].

Minimally Invasive and Robotic-Assisted Surgeries

The increasing adoption of fibrin sealant patches in minimally invasive and robotic-assisted surgeries is another key trend. This shift is expected to enhance patient recovery times and reduce postoperative complications[4].

Financial Trajectory

The fibrin sealant patch market is expected to grow significantly over the forecast period. Here are some key financial projections:

• Market Size in 2022: $0.55 billion[2]
• Projected Market Size in 2032: $1.1 billion[2]
• CAGR from 2023 to 2032: 7.8%[2]
• Market Size in 2023 for Absorbable Fibrin Sealant Patches: $0.3 billion, projected to reach $0.7 billion by 2033[4]

Key Players

Major companies in the global fibrin sealant patch market include Ethicon US, LLC, Baxter, and others. These companies are driving innovation and market growth through their advanced products and strategic market positioning[1].

Conclusion

The fibrin sealant patch market is poised for substantial growth driven by increasing surgical procedures, advancements in surgical techniques, and a growing geriatric population. Despite challenges such as high costs and safety concerns, the market is expected to expand significantly over the next decade.

Key Takeaways

• The global fibrin sealant patch market is projected to reach $1.1 billion by 2032.
• The patch segment holds the highest market share due to its high adoption in general surgeries.
• North America dominates the market due to its advanced healthcare infrastructure and high adoption rates of advanced surgical technologies.
• The risk of anaphylaxis and disease transmission are significant restraints.
• Technological advancements in bioengineered sealants and their use in minimally invasive surgeries are key future trends.

Frequently Asked Questions

Q: What is the primary driver for the growth of the fibrin sealant patch market? A: The primary driver is the increasing number of surgical procedures globally, coupled with advancements in surgical techniques and a growing geriatric population.

Q: Which region holds the largest share of the fibrin sealant patch market? A: North America holds the largest share due to its well-established healthcare infrastructure and high adoption rates of advanced surgical technologies.

Q: What are the main challenges facing the fibrin sealant patch market? A: The main challenges include the high cost of fibrin sealant patches, the availability of alternative products, and the risk of anaphylaxis and disease transmission.

Q: Which companies are major players in the fibrin sealant patch market? A: Major companies include Ethicon US, LLC, Baxter, and others.

Q: What is the projected CAGR for the fibrin sealant patch market from 2023 to 2032? A: The projected CAGR is 7.8% from 2023 to 2032.

Cited Sources

1. Fortune Business Insights - Fibrin Sealant Patch Market Size, Share, & Forecast 2032
2. GlobeNewswire - Fibrin Sealants Market to Reach $1.1 Billion By 2032 | CAGR
3. Transparency Market Research - Fibrin Sealants Market to reach US$ 2 bn by 2031
4. Allied Market Research - Absorbable Fibrin Sealant Patch Market Size, Forecast - 2033
5. Valuates Reports - Global Fibrin Sealant Patch Market Research Report 2023