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Last Updated: April 2, 2025

Ixekizumab - Biologic Drug Details


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Summary for ixekizumab
Tradenames:1
High Confidence Patents:0
Applicants:1
BLAs:1
Suppliers: see list1
Recent Clinical Trials: See clinical trials for ixekizumab
Recent Clinical Trials for ixekizumab

Identify potential brand extensions & biosimilar entrants

SponsorPhase
Karolinska University LaboratoryPhase 2
Vastra Gotaland RegionPhase 2
Gothia Forum - Center for Clinical TrialPhase 2

See all ixekizumab clinical trials

Pharmacology for ixekizumab
Mechanism of ActionInterleukin-17A Antagonists
Established Pharmacologic ClassInterleukin-17A Antagonist
Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for ixekizumab Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for ixekizumab Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for ixekizumab Derived from Patent Text Search

No patents found based on company disclosures

Market Dynamics and Financial Trajectory for the Biologic Drug: Ixekizumab

Introduction to Ixekizumab

Ixekizumab is a biologic drug used primarily to treat moderate to severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. It belongs to the class of IL-17 inhibitors, which target the interleukin-17A cytokine involved in inflammatory processes.

Market Size and Growth

The global ixekizumab market has been experiencing significant growth. As of 2022, the market size was valued at USD 899.22 million. It is projected to reach USD 1,484.85 million by 2030, with a Compound Annual Growth Rate (CAGR) of 6.70% during the forecast period of 2023-2030[1].

Drivers of Market Growth

Several factors are driving the growth of the ixekizumab market:

Rising Prevalence of Psoriasis and Psoriatic Arthritis

The increasing prevalence of psoriasis and psoriatic arthritis globally is a major driver. These conditions are the primary indications for ixekizumab, and their rising incidence directly increases the demand for this medication[1].

Increasing Geriatric Population

The geriatric population is more prone to developing psoriasis and psoriatic arthritis. As the global geriatric population grows, so does the demand for treatments like ixekizumab[1].

Rise in Healthcare Spending

Many countries are allocating significant portions of their healthcare budgets to treat age-related diseases. This increased healthcare spending supports the use of advanced treatments, including biologics like ixekizumab[1].

Research and Development Activities

The rise in research and development activities is expected to lead to advancements, new indications, and increased awareness of ixekizumab. Collaborations between pharmaceutical companies and healthcare providers can further enhance its market presence[1].

Market Segmentation

The ixekizumab market is segmented based on several criteria:

By Drug Class

The market includes interleukin inhibitors and other drug classes. Ixekizumab, being an IL-17 inhibitor, falls under the interleukin inhibitors category[1].

By Demographic

The market is segmented into adult and pediatric demographics. However, the primary focus is on adults due to the higher prevalence of psoriasis and psoriatic arthritis in this age group[1].

By Application

Ixekizumab is used to treat ankylosing spondylitis, psoriatic arthritis, psoriasis, and other conditions. Psoriasis and psoriatic arthritis are the main drivers of market growth[1].

By Dosage Form

The drug is available in subcutaneous solution form, among others. The subcutaneous solution is the most common dosage form for ixekizumab[1].

By End-Users

Hospitals dominate the end-user segment due to the wide range of applications of ixekizumab in these settings. Other end-users include clinics and other healthcare facilities[1].

By Distribution Channel

The distribution channels include hospital pharmacies, retail pharmacies, and online pharmacies. Hospital pharmacies are a significant channel due to the frequent use of ixekizumab in hospital settings[1].

Financial Performance and Projections

Revenue Growth

The revenue growth of ixekizumab is robust, driven by increasing demand and expanding indications. The market is expected to grow from USD 899.22 million in 2022 to USD 1,484.85 million by 2030[1].

Key Players

Eli Lilly and Company is a major player in the ixekizumab market. The company's financial reports indicate strong revenue growth driven by key products, including ixekizumab. For instance, in Q3 2024, Eli Lilly reported a 20% increase in worldwide revenue, partly driven by volume growth of key products like ixekizumab[2].

Challenges and Restraints

Despite the positive growth trajectory, the ixekizumab market faces several challenges:

High Cost Associated with the Drug

The high cost of developing and distributing ixekizumab is a significant restraint. This cost can limit access to the drug, especially in regions with limited healthcare budgets[1].

Side Effects

Ixekizumab is associated with several side effects, including nausea, diarrhea, weight loss, abdominal pain, swelling, rash, hives, and breathing problems. These side effects can deter some patients and healthcare providers from using the drug[1].

Lack of Awareness

Limited awareness about ixekizumab and its benefits can also hinder market growth. Educational campaigns and collaborations between pharmaceutical companies and healthcare providers are essential to address this issue[1].

Competitive Landscape

The global IL-17 biologics market, which includes ixekizumab, is competitive and growing. The market is expected to generate USD 10.9 billion by 2030, up from USD 4.37 billion in 2022, with a CAGR of 12.3% during the forecast period of 2024-2030. Other drugs in this class, such as secukinumab, bimekizumab, and brodalumab, also contribute to the market's growth[4].

Impact of Biosimilars

The emergence of biosimilars can impact the market dynamics of biologic drugs like ixekizumab. While biosimilars can reduce costs and increase access, they also pose a competitive threat to branded biologics. Pharmaceutical companies are investing in their own biosimilar products to mitigate this risk[3].

Conclusion

The ixekizumab market is poised for significant growth driven by increasing prevalence of psoriasis and psoriatic arthritis, rising healthcare spending, and advancements in research and development. However, the market faces challenges such as high costs, side effects, and lack of awareness. Addressing these challenges through educational campaigns, cost management strategies, and continued innovation will be crucial for sustaining market growth.

Key Takeaways

  • The global ixekizumab market is projected to reach USD 1,484.85 million by 2030, growing at a CAGR of 6.70%.
  • Rising prevalence of psoriasis and psoriatic arthritis, increasing geriatric population, and rising healthcare spending are key drivers.
  • High costs, side effects, and lack of awareness are significant restraints.
  • The market is segmented by drug class, demographic, application, dosage form, end-users, and distribution channels.
  • Hospital pharmacies dominate the end-user segment.
  • Eli Lilly and Company is a major player in the ixekizumab market.

FAQs

What is the primary indication for ixekizumab?

Ixekizumab is primarily used to treat moderate to severe plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis.

What is the expected market size of ixekizumab by 2030?

The ixekizumab market is expected to reach USD 1,484.85 million by 2030[1].

What are the major drivers of the ixekizumab market?

The major drivers include the rising prevalence of psoriasis and psoriatic arthritis, increasing geriatric population, and rising healthcare spending[1].

What are the significant challenges facing the ixekizumab market?

High costs associated with the drug, side effects, and lack of awareness are significant challenges[1].

Who are the key players in the ixekizumab market?

Eli Lilly and Company is a major player in the ixekizumab market[2].

Sources

  1. Data Bridge Market Research - Global Ixekizumab Market – Industry Trends and Forecast to 2030
  2. Lilly - Lilly Reports Q3 2024 Financial Results Highlighted by Strong Volume
  3. CAS.org - The Rise of Biologics: Emerging Trends and Opportunities
  4. Business Wire - Global IL-17 Biologics Market Research Report 2023
  5. PR Newswire - Lilly Reports Fourth-Quarter 2022 Financial Results, Core Business Growth and Pipeline Advancements Support Strong Long-Term Outlook

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