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Last Updated: April 21, 2025

Pneumococcal vaccine, polyvalent - Biologic Drug Details


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Summary for pneumococcal vaccine, polyvalent
Tradenames:1
High Confidence Patents:0
Applicants:1
BLAs:1
Suppliers: see list2
Pharmacology for pneumococcal vaccine, polyvalent
Physiological EffectActively Acquired Immunity
Established Pharmacologic ClassInactivated Pneumococcal Vaccine
Chemical StructurePneumococcal Vaccines
Vaccines, Inactivated
Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for pneumococcal vaccine, polyvalent Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for pneumococcal vaccine, polyvalent Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for pneumococcal vaccine, polyvalent Derived from Patent Text Search

No patents found based on company disclosures

Market Dynamics and Financial Trajectory for Pneumococcal Vaccine, Polyvalent

Introduction

The pneumococcal vaccine market, particularly the polyvalent segment, is experiencing significant growth driven by various factors including increased global vaccination campaigns, technological advancements, and rising awareness of pneumococcal infections. Here, we delve into the market dynamics and financial trajectory of the pneumococcal vaccine, polyvalent.

Market Size and Growth Projections

The global pneumococcal vaccine polyvalent market was valued at USD 8.57 billion in 2023 and is projected to reach USD 11.36 billion by 2031, growing at a Compound Annual Growth Rate (CAGR) of 5.9% from 2024 to 2031[1].

Another report indicates that the pneumococcal vaccines market is expected to reach USD 8.80 billion in 2024 and grow at a CAGR of 4.83% to reach USD 11.20 billion by 2029[3].

Key Drivers of Market Growth

Increased Government Support and Awareness

Government support for immunization programs and increased awareness of pneumococcal disease prevention are major drivers of the market. Governments and health organizations globally are promoting vaccination campaigns, which has led to a significant increase in vaccine uptake[1][3].

Technological Advancements

Developments in vaccine technology, such as the introduction of more potent polyvalent formulations, are driving the market forward. For instance, the approval of Pfizer's PREVNAR 20, a 20-valent pneumococcal conjugate vaccine, and Merck's investigational 15-valent pneumococcal conjugate vaccine (V114), are significant advancements[4][5].

Rising Prevalence of Chronic Diseases

The increasing prevalence of chronic diseases that make individuals more vulnerable to infections is another key factor. An aging population and the growing incidence of chronic conditions are boosting the demand for pneumococcal vaccines[1][3].

Expansion into Emerging Markets

The development of healthcare infrastructure in emerging nations and the global acceptance of vaccination by health organizations are also contributing to market growth. The Asia-Pacific region is expected to be one of the fastest-growing markets due to these factors[1][3].

Market Segmentation

Application

The market is segmented based on application, including conjugate vaccines, polysaccharide vaccines, combination vaccines, adult pneumococcal vaccines, and pediatric pneumococcal vaccines. The pneumococcal conjugate vaccine segment is anticipated to witness substantial growth due to ongoing developments and strategic initiatives by market players[1][3].

Product

The market is also segmented by product, including immunization, preventive medicine, pediatric care, elderly care, and travel medicine. These segments are driven by the specific needs of different demographics and healthcare settings[1].

Geographical Regions

North America holds a significant market share due to the presence of established healthcare infrastructure and key market players. However, the Asia-Pacific region is expected to be the fastest-growing market[1][3].

Cost-Effectiveness and Economic Impact

Cost-effectiveness studies have shown that the use of newer pneumococcal vaccines, such as PCV20 alone or PCV15 in series with PPSV23, is cost-saving for adults aged 65 years and older. These vaccines are expected to reduce the incidence of pneumococcal disease, thereby saving healthcare costs in the long run[2].

Competitive Landscape

The market is highly competitive with major players such as Pfizer Inc., Merck & Co., Inc., and others. These companies are continuously investing in the development of advanced pneumococcal vaccines, which intensifies competition and drives innovation. For example, Merck’s V114 and Pfizer’s PREVNAR 20 are recent additions to the market, offering broader serotype coverage[4][5].

Regulatory Environment

Regulatory approvals play a crucial role in the market. Recent approvals, such as the FDA approval for Pfizer's PREVNAR 20 and the positive results from Merck’s Phase 3 studies for V114, are significant milestones. These approvals not only expand the market but also enhance the credibility and efficacy of the vaccines[4][5].

Global Burden of Pneumococcal Disease

The high burden of pneumonia globally, particularly among children, is a significant driver of the market. According to UNICEF, around 2,000 children are affected by pneumonia daily, highlighting the urgent need for effective vaccination strategies[3].

Future Outlook

The future of the pneumococcal vaccine market looks promising with ongoing research and development. New vaccine candidates, such as Sanofi and SK bioscience’s 21-valent conjugate vaccine, are in various stages of clinical trials and are expected to offer broader serotype coverage than current vaccines[4].

Key Takeaways

  • The pneumococcal vaccine polyvalent market is projected to grow significantly, driven by government support, technological advancements, and rising awareness.
  • The market is segmented by application, product, and geographical regions, with North America holding a significant share.
  • Cost-effectiveness studies indicate that newer vaccines are cost-saving and effective in reducing pneumococcal disease incidence.
  • The competitive landscape is intense, with major players continuously innovating and expanding their product portfolios.
  • Regulatory approvals and the global burden of pneumococcal disease are critical factors influencing market growth.

FAQs

What is the projected market size of the pneumococcal vaccine polyvalent market by 2031?

The pneumococcal vaccine polyvalent market is expected to reach USD 11.36 billion by 2031, growing at a CAGR of 5.9% from 2024 to 2031[1].

Which region is expected to be the fastest-growing market for pneumococcal vaccines?

The Asia-Pacific region is anticipated to be the fastest-growing market for pneumococcal vaccines due to the development of healthcare infrastructure and increasing awareness of vaccination[1][3].

What are the key drivers of the pneumococcal vaccine market?

Key drivers include increased government support for immunization programs, technological advancements in vaccine development, and the rising prevalence of chronic diseases that increase vulnerability to infections[1][3].

Are newer pneumococcal vaccines cost-effective?

Yes, cost-effectiveness studies have shown that the use of newer pneumococcal vaccines, such as PCV20 alone or PCV15 in series with PPSV23, is cost-saving for adults aged 65 years and older[2].

Who are the major players in the pneumococcal vaccine market?

Major players include Pfizer Inc., Merck & Co., Inc., and others who are continuously investing in the development of advanced pneumococcal vaccines[4][5].

Sources

  1. Market Research Intellect: Pneumococcal Vaccine Polyvalent Market Size, Industry Share ...
  2. CDC: Use of 15-Valent Pneumococcal Conjugate Vaccine and 20 ...
  3. Mordor Intelligence: Pneumococcal Vaccine Market Size & Share Analysis
  4. Grand View Research: Pneumococcal Vaccine Market Size And Share Report, 2030
  5. Merck: Merck Announces Positive Topline Results from Two Additional Phase 3 Adult Studies Evaluating V114, Merck’s Investigational 15-valent Pneumococcal Conjugate Vaccine

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