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Last Updated: April 13, 2025

Rabies vaccine - Biologic Drug Details


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Summary for rabies vaccine
Recent Clinical Trials for rabies vaccine

Identify potential brand extensions & biosimilar entrants

SponsorPhase
Beijing Contreke Statistical Technology Co., LTDEarly Phase 1
The First Affiliated Hospital of Yunnan University of Traditional Chinese MedicineEarly Phase 1
Anning City First People's HospitalEarly Phase 1

See all rabies vaccine clinical trials

Recent Litigation for rabies vaccine

Identify key patents and potential future biosimilar entrants

District Court Litigation
Case NameDate
Jazz Pharmaceuticals, Inc. v. Avadel CNS Pharmaceuticals, LLC2021-11-10
Jazz Pharmaceuticals, Inc. v. Avadel CNS Pharmaceuticals, LLC2021-05-12
Par Pharmaceutical, Inc. v. Eagle Pharmaceuticals, Inc.2018-05-31

See all rabies vaccine litigation

PTAB Litigation
PetitionerDate
2018-06-22
2013-08-15

See all rabies vaccine litigation

Note on Biologic Patents

Matching patents to biologic drugs is far more complicated than for small-molecule drugs.

DrugPatentWatch employs three methods to identify biologic patents:

  1. Brand-side disclosures in response to biosimilar applications
  2. These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.

  3. General brand-side disclosures
  4. These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

  5. Patents from broad patent text search
  6. For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.

1) High Certainty: US Patents for rabies vaccine Derived from Brand-Side Litigation

No patents found based on brand-side litigation

2) High Certainty: US Patents for rabies vaccine Derived from Company Disclosures

No patents found based on company disclosures

3) Low Certainty: US Patents for rabies vaccine Derived from Patent Text Search

No patents found based on company disclosures

Market Dynamics and Financial Trajectory for Rabies Vaccines

Introduction to Rabies Vaccines

Rabies vaccines are crucial in the prevention and control of rabies, a deadly viral disease that affects humans and animals. The global market for rabies vaccines is driven by several key factors, including the high incidence of rabies, technological advancements, and increasing awareness about the importance of vaccination.

Global Market Size and Growth

The global rabies vaccine market was valued at $1.2 billion in 2022 and is projected to reach $1.9 billion by 2032, growing at a Compound Annual Growth Rate (CAGR) of 4.7% from 2023 to 2032[1].

Key Drivers of Market Growth

High Incidence of Rabies

Rabies remains a significant public health concern globally, particularly in Africa and Asia. According to the World Health Organization, rabies is estimated to cause 59,000 human deaths annually in over 150 countries, with 95% of cases occurring in Africa and Asia. This high incidence drives the demand for rabies vaccines[1].

Technological Advancements

Technological advancements in vaccine development are a major driver of the market. For instance, the introduction of innovative vaccine formulations such as the three-dose recombinant nanoparticle-based G protein rabies vaccine enhances the market dynamics[4].

Increase in Awareness and Government Initiatives

There is a rising awareness among the population regarding the importance of vaccination, which is further supported by government initiatives. In the U.S., for example, the government spends significantly on rabies vaccination, and public awareness campaigns contribute to the growth of the market[1].

Market Segmentation

By Product Type

The market is segmented by product type, including purified chick embryo cell vaccines, which are crucial for both post-exposure and pre-exposure prophylaxis. These vaccines are widely used due to their efficacy and safety profile[4].

By Prophylaxis Type

The market is also segmented by prophylaxis type, including pre-exposure and post-exposure prophylaxis. Pre-exposure prophylaxis is particularly important for individuals at high risk, such as veterinarians and laboratory workers, while post-exposure prophylaxis is critical for those who have been bitten or exposed to potentially rabid animals[4].

By Application

Rabies vaccines are used in various applications, including human and animal health. The human rabies vaccine market is significant due to the high mortality rate associated with the disease, while the animal health segment is driven by the need to control rabies transmission in pets and livestock[3].

By End User

The market is segmented by end users, including hospitals, clinics, veterinary clinics, and research institutions. The demand from these end users is driven by the need for effective rabies prevention and control measures[1].

By Region

North America is anticipated to lead the rabies vaccine market due to a high prevalence of rabies cases and dog bites, alongside robust government and private sector initiatives. Other regions, such as Asia and Africa, also present significant market opportunities due to the high incidence of rabies in these areas[1][4].

Key Market Players

The rabies vaccine market is characterized by the presence of several major players, including:

  • Zoetis Inc.
  • Sanofi SA
  • Merck & Co., Inc.
  • Bharat Biotech International Limited
  • Serum Institute of India Pvt. Ltd.
  • Boehringer Ingelheim International GmbH
  • Elanco Animal Health Incorporated.
  • Novartis AG
  • Virbac SA

These companies are actively involved in developing and distributing vaccines, with recent product launches and strategic partnerships enhancing market dynamics[1][4].

Recent Developments and Collaborations

Recent collaborations and developments in the rabies vaccine market include the approval of new vaccine formulations. For example, YS Biopharma's PIKA rabies vaccine was granted Phase 3 clinical trial approval from the Food and Drug Administration of the Philippines in June 2023, indicating ongoing innovation in the field[1].

Challenges and Restraints

High Cost of Vaccines

One of the significant restraints in the rabies vaccine market is the high cost of vaccines. A typical vaccination series with rabies immunoglobulin can cost anywhere from $2,000 to $7,000+ per person, posing a significant economic burden, especially in low-income countries[5].

Low Immunization Rates in Dogs

Low immunization rates in dogs, particularly in rural and underdeveloped areas, remain a challenge. This is due to limited public awareness and access to veterinary care, which hampers the overall control of rabies transmission[4].

Impact of COVID-19

The COVID-19 pandemic initially hindered the growth of the rabies vaccine market due to lockdowns and a shift in focus towards human health. However, the resurgence of rabies cases post-pandemic has reignited demand for vaccines, contributing to the market's steady growth[4].

Financial Trajectory

The financial trajectory of the rabies vaccine market is positive, driven by the increasing demand for vaccines and ongoing technological advancements. Here are some key financial highlights:

  • Market Size in 2022: $1.2 billion
  • Projected Market Size by 2032: $1.9 billion
  • CAGR: 4.7% from 2023 to 2032
  • Annual Costs: The costs associated with detection, prevention, and control of rabies exceed $300 million annually in the U.S. alone[1].

Regional Market Analysis

North America

North America is expected to witness lucrative growth during the forecast period due to the high presence of market players such as Zoetis, Merck & Co., Inc., and Sanofi SA. Government initiatives and high awareness among the population regarding the importance of vaccination also contribute to the growth in this region[1][4].

Asia and Africa

Asia and Africa present significant market opportunities due to the high incidence of rabies in these regions. Countries like India account for a substantial number of human rabies deaths globally, making these markets critical for vaccine manufacturers[1].

Key Takeaways

  • The global rabies vaccine market is projected to grow significantly due to the high incidence of rabies and technological advancements.
  • North America is expected to lead the market, supported by robust government initiatives and the presence of key market players.
  • The high cost of vaccines and low immunization rates in dogs are significant challenges that need to be addressed.
  • Ongoing innovation and recent collaborations are expected to boost the market growth.

FAQs

What is the current market size of the global rabies vaccine market?

The global rabies vaccine market was valued at $1.2 billion in 2022[1].

What is the projected growth rate of the global rabies vaccine market?

The market is projected to grow at a CAGR of 4.7% from 2023 to 2032[1].

Which region is expected to lead the rabies vaccine market?

North America is anticipated to lead the rabies vaccine market due to the high presence of market players and robust government initiatives[1][4].

What are the major challenges in the rabies vaccine market?

The high cost of vaccines and low immunization rates in dogs are significant challenges in the market[4][5].

Who are the key players in the rabies vaccine market?

Key players include Zoetis Inc., Sanofi SA, Merck & Co., Inc., Bharat Biotech International Limited, and Serum Institute of India Pvt. Ltd.[1].

Sources

  1. Allied Market Research, "Rabies Vaccine Market Statistics, Growth Forecast- 2032"
  2. La Jolla Institute for Immunology, "Rethinking the rabies vaccine"
  3. NewsChannel Nebraska, "Human Rabies Vaccine Market Analysis 2024: Key Dynamics, Top Manufacturers and Global Share Forecast to 2032"
  4. Mordor Intelligence, "Global Rabies Vaccine Market Size (2024 - Mordor Intelligence"
  5. Health and Human Services North Dakota, "Rabies FAQs"

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